Predicting Educational Success in Autism from Social Neuroscience in Infancy: A Longitudinal Investigation from Birth Until 3rd Grade
从婴儿期社会神经科学预测自闭症教育成功:从出生到三年级的纵向调查
基本信息
- 批准号:10393206
- 负责人:
- 金额:$ 24.91万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2021
- 资助国家:美国
- 起止时间:2021-05-01 至 2024-04-30
- 项目状态:已结题
- 来源:
- 关键词:8 year oldAdaptive BehaviorsAddressAffectAgeAge-YearsAwardBehavioralBirthChildChild DevelopmentClinicalClinical assessmentsCommunicationCommunication impairmentCommunitiesComplementConsensusData AnalysesData SetDevelopmentDevelopmental ProcessEarly InterventionEducationEducational InterventionEffectivenessEnvironmentFamilyFriendshipsGoalsGraduation RatesImpairmentIndividualInvestigationLanguageLearningLifeLinkLongevityLongitudinal StudiesLongitudinal cohortMeasurementMeasuresMentorsMentorshipMonitorNeurosciencesOccupationsOutcomeOutcome MeasurePathway interactionsPatternPerformancePhaseProcessReadinessReportingResearchResearch PersonnelRiskSamplingSchoolsServicesSpecial EducationStandardizationStatistical MethodsStudentsSystemTechnologyTestingTimeTrainingUnited States National Institutes of HealthVisualWorkautism spectrum disorderautistic childrenbasecare burdencareerclinical carecognitive functioncohortcostdosageevidence basefirst gradefollow-uphigh schoolimprovedimproved outcomeindividuals with autism spectrum disorderinfancyinsightkindergartenliteracymultidisciplinarynovelpredictive markerprogramssecond gradeskillssocialsocial communicationsocial engagementsocial neurosciencesuccessteacherthird gradetoolvisual tracking
项目摘要
PROJECT SUMMARY/ABSTRACT
The goal of this Pathway to Independence Award (K99/R00) is to promote an independent research career
by complementing the candidate’s training in neuroscience and education with expert mentorship in the
measurement and analysis of social visual engagement (SVE), clinical monitoring of early typical and atypical
social communication development, and novel statistical methods for longitudinal data analysis. The
candidate’s short-term goal is to identify robust, early clinical and SVE predictors of functional communication
skills, kindergarten readiness, and literacy outcomes in children with autism spectrum disorder (ASD) and
related communication disorders (CDs). SVE measures—collected via eye-tracking technology—quantify the
way in which children visually explore, engage with, ultimately learn from, and adapt to their surrounding world
at different stages of life, and may provide key insights into atypical versus typical developmental processes
over the early lifespan. The proposed project will capitalize on an established longitudinal cohort of 268 ASD,
CD, and typically developing children who have, to date, contributed more than 8,000 clinical and 2,300 SVE
measures over 12 time points from birth to age 3. The candidate will collect follow-up SVE, kindergarten
readiness, and literacy development measures on this sample, when children are 5 (kindergarten), 6 (1st
grade), 7 (2nd grade), and 8 (3rd grade) years of age. Longitudinal trajectories of clinical assessment measures
will be tested for prediction of functional communication outcomes at age 3, kindergarten readiness outcomes
at age 5, and literacy development at ages 5, 6, 7, and 8. Patterns and trajectories of SVE will also be
investigated for their association with these developmental outcome measures. The candidate will directly test
the extent to which specific inputs, timing, and dosage (i.e., magnitude and rate) of developmental divergences
in trajectories relate to outcome. This work will provide quantitative, objective, community-viable, performance-
based biomarkers for predicting and monitoring risk of school difficulties, and enable the identification of
actionable targets and developmental windows of opportunity for early intervention in children with ASD and
CDs. The training plan is supported by a multidisciplinary team of mentors—including Drs. Ami Klin, Warren
Jones, Lindee Morgan, and Amy Wetherby—and the strengths of the Marcus Autism Center, one of only five
NIH Autism Centers of Excellence, providing groundbreaking research and clinical care for individuals with
ASD. The intersection of these strengths provides an ideal training environment for promoting the candidate’s
transition to independent investigator, and leading a research program that leverages tools and insights from
social neuroscience to improve early and school-based educational interventions for children with ASD and
CDs.
项目总结/文摘
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
数据更新时间:{{ journalArticles.updateTime }}
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
数据更新时间:{{ journalArticles.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ monograph.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ sciAawards.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ conferencePapers.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ patent.updateTime }}
Laura Edwards其他文献
Laura Edwards的其他文献
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
{{ truncateString('Laura Edwards', 18)}}的其他基金
Predicting Educational Success in Autism from Social Neuroscience in Infancy: A Longitudinal Investigation from Birth Until 3rd Grade
从婴儿期社会神经科学预测自闭症教育成功:从出生到三年级的纵向调查
- 批准号:
10414834 - 财政年份:2021
- 资助金额:
$ 24.91万 - 项目类别:
Predicting Educational Success in Autism from Social Neuroscience in Infancy: A Longitudinal Investigation from Birth Until 3rd Grade
从婴儿期社会神经科学预测自闭症教育成功:从出生到三年级的纵向调查
- 批准号:
10627920 - 财政年份:2021
- 资助金额:
$ 24.91万 - 项目类别:
相似海外基金
Spatiotemporal dynamics of acetylcholine activity in adaptive behaviors and response patterns
适应性行为和反应模式中乙酰胆碱活性的时空动态
- 批准号:
24K10485 - 财政年份:2024
- 资助金额:
$ 24.91万 - 项目类别:
Grant-in-Aid for Scientific Research (C)
Neuroanatomical pathways of the mouse olfactory tubercle and odor-induced adaptive behaviors
小鼠嗅结节的神经解剖通路和气味诱导的适应性行为
- 批准号:
16K18377 - 财政年份:2016
- 资助金额:
$ 24.91万 - 项目类别:
Grant-in-Aid for Young Scientists (B)
Effects of the Video Self-Modeling on Adaptive Behaviors of Students with Autism Spectrum Disorders
视频自我塑造对自闭症谱系障碍学生适应性行为的影响
- 批准号:
22531069 - 财政年份:2010
- 资助金额:
$ 24.91万 - 项目类别:
Grant-in-Aid for Scientific Research (C)
BIC: EMT: Cooperative and Adaptive Behaviors By Molecular Robots
BIC:EMT:分子机器人的合作和适应性行为
- 批准号:
0523317 - 财政年份:2005
- 资助金额:
$ 24.91万 - 项目类别:
Continuing Grant
Adaptive behaviors emerged by functional structures in interaction networks
交互网络中功能结构出现的适应性行为
- 批准号:
17075007 - 财政年份:2005
- 资助金额:
$ 24.91万 - 项目类别:
Grant-in-Aid for Scientific Research on Priority Areas
A STUDY OF THE ADAPTIVE BEHAVIORS OF DELINQUENT YOUTH
青少年犯罪适应性行为研究
- 批准号:
3025358 - 财政年份:1986
- 资助金额:
$ 24.91万 - 项目类别:
A STUDY OF THE ADAPTIVE BEHAVIORS OF DELINQUENT YOUTH
青少年犯罪适应性行为研究
- 批准号:
3025357 - 财政年份:1984
- 资助金额:
$ 24.91万 - 项目类别: