NIGMS Administrative Supplements to Support Undergraduate Summer Research

父母补助金行政补充R 01 GM 128145 解决计算基因组注释的开放性挑战 PI Mark Borodovsky 摘要 提高真核基因组中的基因发现是亲本的一个大而重要的组成部分 提议与安德烈Zaznaev，格鲁吉亚技术院长的名单大三学生，谁是非常 有兴趣在计算生物学方面做出贡献，我们将致力于其他目标， 该提案-开发一种改进的真核基因组基因预测算法 其特点是其复杂性-基因组GC的长程和短程不均匀性 混合物.本科生将创建用于生成GC库的工具- 每个基因组中蛋白质编码区的依赖模型。他还将开发一个扩展 基因发现算法的一部分，它将能够使用新的模型。

Administrative Supplement to Parent Grant R01 GM128145 Addressing Open Challenges of Computational Genome Annotation PI Mark Borodovsky Abstract Improving gene finding in eukaryotic genomes is a large and important part of the parent proposal. With Andrey Zaznaev, the Georgia Tech Deans’s list junior student, who is very interested in making contribution in computational biology, we will work on additional aim of the proposal – developing an improved algorithm for gene prediction in eukaryotic genomes that are distinguished by their complexity - long- and short-range inhomogeneity of genome GC composition. The undergraduate student will create tools for generating a library of GC- dependent models of protein-coding regions in each genome. He also will develop an extension of the gene finding algorithm that will be able to use the new models.