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Center for Community Health: Addressing Regional Maryland Environmental Determinants of Disease

社区健康中心：解决马里兰州地区疾病的环境决定因素

基本信息

批准号：
10394475
负责人：
Marsha Wills-Karp
金额：
$ 140.57万
依托单位：
JOHNS HOPKINS UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
2022
资助国家：
美国
起止时间：
2022-06-24 至 2026-03-31
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10394475
关键词：
Address Affect Allergens Animal Feed Attention Baltimore Big Data Bioinformatics Biological Biometry Chemicals Cities Climate Clinical Communication Communities Community Health Core Facility Data Decision Making Development Discipline Disease District of Columbia Educational workshop Environmental Exposure Environmental Health Environmental Risk Factor Exposure to Faculty Federal Government Fostering Funding Future Gases Health Health Policy Health Promotion Health Sciences Human In Vitro Individual Industrialization Industry Investigation Knowledge Leadership Link Local Government Maryland Mentors Metals Mission Modeling NCI Scholars Program National Institute of Environmental Health Sciences Natural Gas Neighborhood Health Center Neurologic Outcome Particulate Pennsylvania Personal Satisfaction Policies Polychlorinated Biphenyls Population Population Study Positioning Attribute Predisposition Prevention Production Public Health Public Health Practice Research Research Design Research Personnel Risk Assessment Science Scientist Source Strategic Planning Strategic vision Structure Time Training Translating Translational Research Translations Universities Urban Developments Washington adverse outcome built environment cardiorespiratory fitness career development cohort college community engaged research community engagement data to knowledge disorder prevention environmental justice evidence base health science research human subject improved in vivo laboratory equipment member metabolomics multidisciplinary nervous system disorder response skills social translational pipeline vapor vulnerable community

项目摘要

ABSTRACT (OVERALL) The Johns Hopkins University (JHU) proposes the creation of the Center for Community Health: Addressing Regional Maryland Environmental Determinants of Diseases (CHARMED). The strategic vision of the Center is to serve as the nexus of community-engaged environmental research at JHU and in the Maryland region (Washington DC, Baltimore (referred to as CHARM City) and Pennsylvania) by providing focus, research, and leadership for promotion of transformative environmental health science research that will improve human health. The overarching mission is to understand how exposures to environmental factors cause adverse health outcomes and then to translate these findings into action to protect and promote the health and well-being of vulnerable communities in the Maryland region. This mission has been informed by and will continue to be guided by strong partnerships between community leaders and CHARMED members (59) drawn from the JHU and the University of Maryland at College Park. The synergistic combination of basic, population and community- engagement scientists within CHARMED promotes translational research that addresses fundamental questions and translates knowledge into action to have a major impact on human health in the Maryland region, consistent with the NIEHS Strategic Plan. Our mission is accomplished through five aims. Aim 1: Advance translational environmental health research that will improve community health outcomes in the Maryland region as it relates to the thematic foci of the Center. The Thematic Research Groups are: 1) Cardiorespiratory Health and Airborne Contaminants; 2) Chemical Mixtures and Emerging Contaminants, and Health; 3) Community, Social, and Environmental Determinants of Health; and 4) Neurological Health. Aim 2. Promote translation of data to knowledge to action by creating and strengthening strategic partnerships with communities and stakeholders to address environmental health challenges and help set the research agenda of CHARMED using community- engaged research approaches (Community Engagement Core). Aim 3. Establish and support a facility core structure [Integrated Health Sciences Facility Core (IHSFC), and Exposure Characterization and Modeling Facility Core (ECMC)] that enables the mission. The IHSFC will provide assistance with human subject study design, and employ biostatistical, big data, and bioinformatic analyses and integrate “omics” including metabolomics data to predict adverse outcomes. Aim 4. Build capacity in environmental health through a comprehensive strategy that includes fostering (career development, Core Workshops), and supporting (ESI Mentored Scholars Program, pilot funds, access to facility cores) both early stage and senior investigators conducting community environmental health research for the first time. Harnessing the scientific capacity of the Center will facilitate translation of the Center’s research findings into evidence-based approaches for environmental exposure mitigation and disease prevention to improve human health in Maryland and beyond.

文摘(整体)