CACHET - Pilot Project

CACHET - 试点项目

• 批准号: 10394646
• 负责人: Gokhan M. Mutlu
• 金额: $ 22.18万
• 依托单位: UNIVERSITY OF CHICAGO
• 依托单位国家: 美国
• 财政年份: 2017
• 资助国家: 美国
• 起止时间: 2017-09-30 至 2027-03-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10394646
• 关键词: Abbreviations; Address; Applications Grants; Area; Aryl Hydrocarbon Receptor; Award; Biological Markers; Cell physiology; Centers for Disease Control and Prevention (U.S.); Chicago; Clinical Sciences; Clinical and Translational Science Awards; Collaborations; Communities; Core Facility; Data; Development; Discipline; Environment; Environmental Exposure; Environmental Health; Environmental Risk Factor; Faculty; Focus Groups; Fostering; Funding; Funding Agency; Future; Grant; Growth; Health; Health Sciences; Illinois; Institution; Lead; Leadership; Mentors; Methods; Molecular; National Institute of Environmental Health Sciences; Occupational Health; Participant; Pilot Projects; Plant Roots; Program Development; Progress Reports; Public Health Schools; Publications; Request for Applications; Research; Research Personnel; Research Project Grants; Resources; SARS-CoV-2 infection; Testing; Time; Toxic effect; Translational Research; United States National Institutes of Health; Universities; Work; career; career development; clinical center; community based participatory research; community based research; community engagement; design; environmental justice; ethnic health disparity; health disparity; health science research; high reward; high risk; innovation; inter-institutional; member; next generation; non-alcoholic fatty liver disease; programs; racial and ethnic; recruit; response; success

1. PILOT PROJECT PROGRAM: ABSTRACT The ChicAgo Center for Health and EnvironmenT (CACHET) Pilot Project Program is designed to fund new directions in environmental health sciences (EHS) research and provide a primary mechanism for developing the careers of CACHET members. The Pilot Project Program is critical to promoting the success of CACHET investigators and the development of future CACHET resources in EHS research. Indeed, in the current abbreviated funding cycle, this program funded 28 pilot awards totaling $639,000 in research dollars to Center members. To date, these awards have directly led to five NIH-funded R01 and one K08 grants totaling $11,329,383, while five submitted grants are pending and four were submitted but not funded. Pilot projects awarded through this program explore new EHS research areas, build research collaborations and teams (within each institution, between the two institutions and externally), support the next generation of EHS researchers and accelerate external grant support of CACHET members. Proposals that consider data collected by the Community Engagement Core (CEC) as well as proposals that actively collaborate with CEC community participants are encouraged. This focus enables CACHET to directly address the environmental research needs of the community and, in so doing, undertake research aimed at mitigating racial and ethnic health disparities as a function of adverse environmental factors. Innovative and high-risk/high-reward studies are also encouraged. The Pilot Project Program has four primary award types: Young Investigator Award, Idea Award, Focused Research Award and Inter-Institutional Award; each addresses specific needs for building and supporting a strong EHS research community in Chicago. Proposals are reviewed for scientific merit, feasibility, community- relevance, and potential to lead to external grants in EHS research from NIEHS and other funding agencies. Funds awarded by the program are not only essential for cultivating the careers of junior investigators by enhancing their success in obtaining grants and publications, but also for attracting established investigators from other disciplines into the EHS research field and fostering new collaborations. We are confident that in the next five years, the Pilot Project Program will result in a substantial increase in NIEHS funding for CACHET investigators, will noticeably expand EHS research capacity in Chicago, fostering the next generation of EHS researchers and will meaningfully impact the local community.

1.试点项目：摘要 芝加哥健康与环境中心（CACHET）试点项目计划旨在资助新的 环境健康科学（EHS）研究的方向，并提供了发展的主要机制 CACHET成员的职业生涯。试点项目计划对于促进CACHET的成功至关重要 研究人员和未来的CACHET资源在EHS研究的发展。事实上，在目前 缩短了资助周期，该计划资助了28个试点奖项，共计639，000美元的研究资金，以中心 成员迄今为止，这些奖项已直接导致五个NIH资助的R 01和一个K 08赠款总额 11，329，383美元，5笔已提交的赠款待决，4笔已提交但未供资。试点项目 通过该计划授予探索新的EHS研究领域，建立研究合作和团队（在 每个机构，两个机构之间和外部），支持下一代EHS研究人员 并加快CACHET成员的外部赠款支持。考虑到联合国系统收集的数据的建议 社区参与核心（CEC）以及与CEC社区积极合作的建议 与会者受到鼓励。这种关注使CACHET能够直接满足环境研究的需求 在这样做的时候，开展旨在减少种族和族裔健康差距的研究， 不利环境因素的作用。创新和高风险/高回报的研究也受到鼓励。 试点项目计划有四个主要奖项类型：青年研究者奖，创意奖，重点 研究奖和机构间奖;每一个都解决了建立和支持一个 在芝加哥有一个强大的EHS研究社区。对提案进行科学价值、可行性、社区- 相关性，并有可能导致从NIEHS和其他资助机构的EHS研究外部赠款。 该计划授予的资金不仅对培养初级调查员的职业生涯至关重要， 提高他们在获得赠款和出版物方面的成功率，但也有助于吸引知名调查人员 从其他学科进入EHS研究领域，并促进新的合作。我们相信，在 在未来5年内，试点项目计划将导致国家环境卫生服务体系对CACHET的资助大幅增加 研究人员，将显着扩大EHS的研究能力在芝加哥，培养下一代的EHS 研究人员，并将有意义地影响当地社区。