CACHET - Pilot Project

CACHET - 试点项目

• 批准号: 10641985
• 负责人: Gokhan M. Mutlu
• 金额: $ 22.18万
• 依托单位: UNIVERSITY OF CHICAGO
• 依托单位国家: 美国
• 财政年份: 2017
• 资助国家: 美国
• 起止时间: 2017-09-30 至 2027-03-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10641985
• 关键词: Abbreviations; Acceleration; Address; Applications Grants; Area; Aryl Hydrocarbon Receptor; Award; Biological Markers; Cell physiology; Chicago; Clinical Sciences; Clinical and Translational Science Awards; Collaborations; Communities; Core Facility; Data; Development; Discipline; Disparity; Environment; Environmental Exposure; Environmental Health; Environmental Risk Factor; Faculty; Focus Groups; Fostering; Funding; Funding Agency; Future; Grant; Growth; Health; Health Sciences; Illinois; Institution; Leadership; Mentors; Methods; Molecular; National Institute of Environmental Health Sciences; Occupational Health; Participant; Pilot Projects; Program Development; Progress Reports; Public Health Schools; Publications; Request for Applications; Research; Research Personnel; Research Project Grants; Resources; SARS-CoV-2 infection; Testing; Toxic effect; Translational Research; United States National Institutes of Health; Universities; Work; career; career development; clinical center; community based participatory research; community based research; community engagement; design; environmental justice; ethnic health disparity; health disparity; health science research; high reward; high risk; innovation; inter-institutional; member; next generation; non-alcoholic fatty liver disease; programs; racial health disparity; recruit; response; success

1. PILOT PROJECT PROGRAM: ABSTRACT The ChicAgo Center for Health and EnvironmenT (CACHET) Pilot Project Program is designed to fund new directions in environmental health sciences (EHS) research and provide a primary mechanism for developing the careers of CACHET members. The Pilot Project Program is critical to promoting the success of CACHET investigators and the development of future CACHET resources in EHS research. Indeed, in the current abbreviated funding cycle, this program funded 28 pilot awards totaling $639,000 in research dollars to Center members. To date, these awards have directly led to five NIH-funded R01 and one K08 grants totaling $11,329,383, while five submitted grants are pending and four were submitted but not funded. Pilot projects awarded through this program explore new EHS research areas, build research collaborations and teams (within each institution, between the two institutions and externally), support the next generation of EHS researchers and accelerate external grant support of CACHET members. Proposals that consider data collected by the Community Engagement Core (CEC) as well as proposals that actively collaborate with CEC community participants are encouraged. This focus enables CACHET to directly address the environmental research needs of the community and, in so doing, undertake research aimed at mitigating racial and ethnic health disparities as a function of adverse environmental factors. Innovative and high-risk/high-reward studies are also encouraged. The Pilot Project Program has four primary award types: Young Investigator Award, Idea Award, Focused Research Award and Inter-Institutional Award; each addresses specific needs for building and supporting a strong EHS research community in Chicago. Proposals are reviewed for scientific merit, feasibility, community- relevance, and potential to lead to external grants in EHS research from NIEHS and other funding agencies. Funds awarded by the program are not only essential for cultivating the careers of junior investigators by enhancing their success in obtaining grants and publications, but also for attracting established investigators from other disciplines into the EHS research field and fostering new collaborations. We are confident that in the next five years, the Pilot Project Program will result in a substantial increase in NIEHS funding for CACHET investigators, will noticeably expand EHS research capacity in Chicago, fostering the next generation of EHS researchers and will meaningfully impact the local community.

1.试点方案：摘要 芝加哥健康与环境中心(Cachet)试点项目计划旨在为新的 环境健康科学(EHS)研究的方向，并提供发展的主要机制 声望会员的职业生涯。试点项目计划是促进威望成功的关键 EHS研究中的研究人员和未来声望资源的开发。的确，在目前的情况下 缩短的资助周期，该计划资助了28个试点奖项，总计63.9万美元的研究资金给中心 会员。到目前为止，这些奖励已经直接导致了五项由NIH资助的R01和一项K08资助，总计 11 329 383美元，5个已提交赠款待决，4个已提交但未获资助。试点项目 通过该计划获奖探索新的EHS研究领域，建立研究协作和团队(在 每个机构，在两个机构之间和外部)，支持下一代EHS研究人员 并加快对纪念碑会员的外部赠款支持。考虑由 社区参与核心(CEC)以及积极与CEC社区协作的建议 鼓励参与者参加。这一重点使Cachet能够直接满足环境研究的需求 并在这样做的过程中进行旨在缓解种族和族裔健康差距的研究，如 不利环境因素的作用。创新和高风险/高回报的研究也受到鼓励。 试点项目计划有四种主要奖项类型：青年研究人员奖、创意奖、专注奖 研究奖和机构间奖；每个奖项都解决了建立和支持 芝加哥强大的EHS研究社区。建议被审查的科学价值，可行性，社区- 相关性，并有可能从NIEHS和其他资助机构获得EHS研究的外部赠款。 该项目提供的资金不仅对培养初级侦探的职业生涯至关重要，而且 加强他们在获得赠款和出版物方面的成功，但也为了吸引老牌调查人员 从其他学科进入EHS研究领域，并促进新的合作。我们有信心在未来 未来五年，试点项目计划将导致NIEHS为声望提供的资金大幅增加 调查人员，将显著扩大芝加哥的EHS研究能力，培养下一代EHS 并将对当地社区产生有意义的影响。