Design Improvements and Evaluation of a Knee Stress-Relief Powered Exoskeleton for Veterans with Knee Osteoarthritis
针对患有膝骨关节炎的退伍军人的膝关节应力消除动力外骨骼的设计改进和评估
基本信息
- 批准号:10396474
- 负责人:
- 金额:--
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2021
- 资助国家:美国
- 起止时间:2021-04-01 至 2025-03-31
- 项目状态:未结题
- 来源:
- 关键词:Activities of Daily LivingAddressAdultAgeAnalgesicsArticular Range of MotionBiomechanicsCanadaClinicClinical TrialsDegenerative polyarthritisDevelopmentDevicesDisease ProgressionEvaluationFloorGaitGuidelinesHealthHealth systemHealthcare SystemsHuman EngineeringImpairmentIndividualIntakeInternationalInterruptionInterventionKneeKnee OsteoarthritisKnowledgeLaboratoriesLaboratory ResearchLaboratory StudyLeadLengthLife StyleLongevityMechanicsMedicalMedical centerMental DepressionMilitary PersonnelMotorMuscleObesityOperative Surgical ProceduresOpioidOutcomePainPain managementParticipantPatientsPerformancePersonsPharmaceutical PreparationsPhasePhysical PerformancePhysical activityPhysical therapyPopulationProtocols documentationPublishingQuality of lifeQuebecQuestionnairesRecommendationReportingResearchResearch PersonnelRetrievalSensorySeveritiesSiteSocializationSocietiesStressSymptomsSystemTechnologyTestingTimeUnited StatesUnited States Department of Veterans AffairsUnited States Food and Drug AdministrationVeteransWaiting ListsWalkingWeight maintenance regimenWorkWritingactive dutyaddictioncombatcompare effectivenessdesigndisabilityexoskeletonexoskeleton deviceexperiencefootimprovedimproved mobilityinjuredjoint loadingknee painknee replacement arthroplastymilitary veteranneurological rehabilitationpain perceptionpain reductionpowered exoskeletonresponserobot exoskeletonsatisfactiontrendusabilitywalking speedweight loss program
项目摘要
Knee osteoarthritis (OA) is a growing problem due to increased longevity and obesity with estimates of 14 million
people living with this impairment. Knee OA results in decreased activity and lifestyle changes, further
exacerbating an individual’s health. Exoskeleton technology (Keeogo™, B-temia, Inc.) may be a viable alternative
to standard knee OA treatment by providing powered support to reduce pain during mobility. Preliminary
studies with the Keeogo™ in six persons with knee OA showed efficacy for pain reduction during different
mobility tasks. However, a tuning guide to promote better usability by clinicians and Veterans with knee OA,
knowledge about the biomechanics of how the device provides active assistance, and an in-laboratory evaluation
of performance outcomes compared with standard knee braces are lacking. Absence of published prescription,
tuning and general guidelines for use in Veterans with knee OA were also identified as limitations.
This proposal has four aims: Aim 1) to develop a knee OA-specific tuning guide for KeeogoTM that would
maximize user mobility activities with reduced pain across different levels of severity of knee OA; Aim 2) to
examine the biomechanical responses of Veterans with knee OA to the active assistance provided by the Keeogo™
as compared with the passive assistance provided by standard knee braces; Aim 3) to evaluate in-laboratory
mobility outcomes, pain perception, and user satisfaction with the KeeogoTM as compare with standard knee
braces; and Aim 4) to develop recommendations for prescribing and tuning the use of knee OA exoskeleton
devices. Aims 1 and 4 are development projects and no hypotheses are generated. The two hypotheses (H) to be
tested for Aim 2 are: H2.1) in stance phase, walking with KeeogoTM will show less knee adduction moment
(KAM), knee flexion moment (KFM), and muscle co-contraction than walking with standard knee braces. These
variables have been shown to be related to internal joint loading as well as disease progression and pain; H2.2)
in swing phase, walking with KeeogoTM will show greater knee range of motion (ROM), stride length, and foot
clearance than walking with standard knee braces. These variables have been shown to be related to antalgic gait
as a result of knee pain. The two hypotheses to be tested for Aim 3 are: H3.1) to show improved performance
outcomes on mobility tests, including a 6-minute walk test, timed up and go test, 13-step stair test, pick up penny
from floor test, and the Short Physical Performance Battery (SPPB) when using the KeeogoTM as compared with
their prescribed knee braces and H3.2) to show reduced pain with the KeeogoTM by the numeric pain rating scale
(NPRS) as compared with their prescribed knee braces for the mobility tests.
The study will be conducted at two VA medical centers. The knee OA-specific tuning protocol will be developed
(Aim 1) and used in the in-laboratory evaluations (Aim 3) in 20 and 26 Veterans with knee OA, respectively, at
the James J. Peters VA Medical Center, Bronx, NY. The biomechanical studies (Aim 2) will be conducted in 24
Veterans with knee OA at the VA Pittsburgh Health System-Human Engineering Research Laboratories,
Pittsburgh, PA. The investigators from both sites will work together to write the prescription and tuning
guidelines (Aim 4) for public use.
Expected outcomes: The tuning guide will facilitate quicker fitting and parameter adjustment, the biomechanics
studies are expected to identify underlying mechanisms of action during device use, the in-laboratory study is
expected to demonstrate improved walking velocities, stair ascent/descent times, improved sit-to-stand, stand-
to-sit, and object retrieval from the floor with reduced patient-reported pain; and the knee OA-specific
prescription and tuning guidelines will be deliverable for public use.
由于寿命延长和肥胖,膝关节骨性关节炎(OA)是一个日益严重的问题,估计有1400万人
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Dan Ding其他文献
Dan Ding的其他文献
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{{ truncateString('Dan Ding', 18)}}的其他基金
Design Improvements and Evaluation of a Knee Stress-Relief Powered Exoskeleton for Veterans with Knee Osteoarthritis
针对患有膝骨关节炎的退伍军人的膝关节应力消除动力外骨骼的设计改进和评估
- 批准号:
10186887 - 财政年份:2021
- 资助金额:
-- - 项目类别:
Design Improvements and Evaluation of a Knee Stress-Relief Powered Exoskeleton for Veterans with Knee Osteoarthritis
针对患有膝骨关节炎的退伍军人的膝关节应力消除动力外骨骼的设计改进和评估
- 批准号:
10574518 - 财政年份:2021
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Development of Vision-Guided Shared Control for Assistive Robotic Manipulators
辅助机器人机械手视觉引导共享控制的开发
- 批准号:
10833461 - 财政年份:2020
- 资助金额:
-- - 项目类别:
Development of Vision-Guided Shared Control for Assistive Robotic Manipulators
辅助机器人机械手视觉引导共享控制的开发
- 批准号:
10407465 - 财政年份:2020
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6934013 - 财政年份:2005
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