Linking Alcohol Use Disorder and Social Anxiety Disorder: The Role of Positive Emotions

将酒精使用障碍和社交焦虑障碍联系起来：积极情绪的作用

• 批准号: 10395958
• 负责人: Sarah Dreyer-Oren
• 金额: $ 3.06万
• 依托单位: MIAMI UNIVERSITY OXFORD
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-03-18 至 2022-11-17
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10395958
• 关键词: Address; Alcohol abuse; Alcohol consumption; Alcohols; Anxiety; Area; Automobile Driving; Clinical; Data Analyses; Development; Disease; Ecological momentary assessment; Effectiveness; Elderly; Emotions; Foundations; Fright; Goals; Health; Healthcare; Impairment; Individual; Intervention; Lead; Link; Manuscripts; Mental Depression; Methodology; Methods; Modeling; Occupational Status; Outcome; Participant; Persons; Play; Populations at Risk; Post-Traumatic Stress Disorders; Prevention; Process; Public Health; Publications; Reporting; Research; Research Proposals; Resources; Rewards; Risk; Risk Factors; Role; Scientist; Social Anxiety Disorder; Social Interaction; Social support; Symptoms; Testing; Theoretical model; Training; Work; alcohol comorbidity; alcohol effect; alcohol related problem; alcohol reward; alcohol risk; alcohol use disorder; anxiety symptoms; associated symptom; career; comorbidity; cost; depressive symptoms; drinking; emotion regulation; experience; functional disability; hazardous drinking; insight; positive emotional state; research study; sobriety; social anxiety; social situation; symposium; tool; trait; young adult

PROJECT SUMMARY The proposed research study applies positive emotion regulation models to identify within-person and between-person transdiagnostic mechanisms that contribute to comorbid Alcohol Use Disorder (AUD) and Social Anxiety Disorder (SAD). SAD is an important risk factor for the development of AUD, and comorbid SAD and AUD confer greater detrimental effects on public health-related outcomes than either disorder alone. Building on critical foundational work using negative emotion regulation models to explain comorbid AUD and SAD, the current proposal focuses on positive emotion regulation, particularly difficulty accepting positive emotions, which may also play a critical role in driving comorbidity. Past research has established that people high in SAD symptoms have difficulties regulating positive emotions, including difficulty accepting positive emotions. Although people with AUD often experience deficits in positive emotion regulation in their daily lives (i.e., when sober), there is evidence suggesting that, in the short term, alcohol use facilitates adaptive positive emotion regulation. For example, a recent ecological momentary assessment (EMA) study found that alcohol weakened the relation between state SAD symptoms and reported social interaction quality. Specifically, when participants did not consume alcohol, state SAD symptoms predicted worse social interaction quality, but when they did consume alcohol, state SAD symptoms did not affect social interaction quality. Thus, an understudied area of research is whether alcohol consumption temporarily allows individuals with elevated SAD symptoms to accept positive emotions, which, in the long term, could lead to alcohol-related problems. Aim 1: Using EMA methodology, test whether, on a within-person level, alcohol consumption moderates the day-to-day temporal relation between state SAD symptoms and difficulty accepting positive emotions in young adults at risk for both AUD and SAD. It is expected that greater state social anxiety symptoms will predict greater difficulty accepting positive emotions, but alcohol will moderate (weaken) this relation. Aim 2: Test whether, on a between-person level, the extent to which alcohol helps people accept positive emotions is associated with alcohol-related problems across participants. It is expected that the effectiveness of alcohol in reducing the deleterious impact of SAD on difficulty accepting positive emotions will be correlated with greater alcohol-related problems. By clarifying whether alcohol consumption’s benefit to positive emotion regulation (e.g., increasing acceptance of positive emotions) contributes to problematic alcohol use, results of this study may provide preliminary evidence of important public health-related targets for prevention and intervention in those at risk for AUD. This research proposal and corresponding training plan allow the applicant to obtain extensive training in EMA methods and data analysis tools and provide opportunities for professional development (e.g., conference presentations, manuscript publications, grantsmanship), both of which are fundamental to the applicant’s career goal of becoming an independent clinical scientist studying comorbid anxiety and AUD.

项目总结 建议的研究应用积极情绪调节模型来识别个人内部和 导致酒精使用障碍(AUD)的人与人之间的相互诊断机制 社交焦虑障碍(SAD)。SAD是AUD发生的重要危险因素，与SAD并存 与任何一种疾病相比，AUD对公共卫生相关结果的有害影响更大。 建立在批判性基础工作的基础上，使用负面情绪调节模型来解释并存的AUD和 可悲的是，目前的建议侧重于积极的情绪调节，特别是难以接受积极的情绪 情绪，这也可能在推动合并症方面发挥关键作用。过去的研究表明，人们 高度忧郁症症状难以调节积极情绪，包括难以接受积极情绪 感情。尽管AUD患者在日常生活中经常经历积极情绪调节的缺陷 (即清醒时)，有证据表明，在短期内，饮酒有助于适应积极 情绪调节。例如，最近的一项生态瞬时评估(EMA)研究发现，酒精 削弱了状态SAD症状和报告的社交质量之间的关系。具体地说，当 参与者没有饮酒，状态SAD症状预示着更差的社交质量，但当 他们确实饮酒，表示SAD症状不会影响社交质量。因此，一个未被研究的人 研究领域是酒精消费是否暂时允许患有SAD症状的人 接受积极的情绪，从长远来看，这可能会导致与酒精相关的问题。目标1：使用EMA 方法，测试在个人水平上，饮酒是否缓和日常时间 青少年抑郁症状与难以接受积极情绪的关系 AUD和SAD。预计更严重的社交焦虑症状将预示着接受更大的困难 积极的情绪，但酒精会缓和(削弱)这种关系。目标2：测试，在人与人之间 水平，酒精帮助人们接受积极情绪的程度与酒精相关 参与者之间的问题。预计酒精在减少有害影响方面的有效性 难以接受积极情绪的SAD将与更大的酒精相关问题相关。通过 澄清饮酒是否有利于积极的情绪调节(例如，提高对 积极情绪)导致有问题的饮酒，这项研究的结果可能会提供初步的 与公共卫生有关的重要目标的证据，用于预防和干预澳元缺乏症高危人群。这 研究方案和相应的培训计划允许申请者获得EMA方面的广泛培训 方法和数据分析工具，并为专业发展提供机会(例如，会议 演示文稿、手稿出版物、资质)，这两者都是申请人 职业目标是成为一名研究共病焦虑和AUD的独立临床科学家。