Improving Diversity, Inclusion, and Retention in BackinAction/AcuOA

总结 据估计，只有不到三分之一的临床试验在最初的研究范围内招募了目标样本量。 预测的时间范围，完成临床试验的研究参与者更有可能是男性， 更年轻，收入更高，受教育程度更高。对于服务不足和黑人的临床试验， 土著和有色人种（BIPOC）社区，还有其他挑战与维护 与参与者的接触，他们的生活可能包括更多的短暂性和实际障碍，如交通 障碍，缺乏儿童保育，竞争的优先事项等。此外，没有已知的研究专门研究 改善征聘和留用的机制，更不用说进一步确保 患者样本，用于CIH的临床试验。对目前资助的UH3的改进包括开发和 利用招募和保留（DRR）顾问委员会的多样性，其中包括既往患有 有中西医结合临床试验经验的临床医生，有中西医结合经验的临床医生， 有最少的综合医学经验。此外，该补充增加了招聘和保留 协调该咨询委员会并开展活动以实现其三个目标的专家。通过 利用招募和保留专家以及患者和护理人员多样性，招募， 和保留（DRR）顾问委员会，我们提出的研究设计将提供基于证据的招募 与失访相关的风险因素的工具和重要信息。我们还将实施 一个实时解决这些问题的模型，以确保更大规模研究的成功。我们将参与 与选择不参与主要研究的患者和有风险的患者进行结构化访谈， 退学了此外，我们还建议对社会经济和健康状况进行二级数据分析， 有助于患者选择和完成临床中西医结合试验的护理利用因素。 这项补充研究的主要成果包括开发示范招聘和保留工具 以及从经验上理解导致招募、失访和 成功完成临床试验，如主要HEAL研究。这项研究将是第一个 仔细检查CIH临床试验参与者的性质。这些发现将与 概念化和实施未来的综合医学试验，并将有更广泛的用途， 未来的临床研究寻求招募和留住更多不同的参与者。

SUMMARY It is estimated that less than one-third of clinical trials recruit their target sample size within the originally predicted time frame and that research participants who complete a clinical trial are more likely to be male, younger, have higher incomes, and be more educated. For clinical trials working with underserved and Black, Indigenous, and People of Color (BIPOC) communities, there are additional challenges tied to maintaining contact with participants whose lives may include more transience and practical barriers such as transportation barriers, lack of childcare, competing priorities, etc. Further no study known has specifically examined mechanisms for improving recruitment and retention, let alone a process that further assures diversity in the patient sample, for clinical trials of CIH. Enhancement to the current funded UH3 include the development and utilization of a diversity in recruitment and retention (DRR) advisory board that includes patients with previous integrative medicine clinical trial experience, clinicians with integrative medicine experience, and clinicians who have minimal integrative medicine experience. In addition this supplement adds a recruitment and retention specialist who will coordinate this advisory board and implement the activities to meet its three aims. Through the utilization of both a recruitment and retention specialist and a patient and caregiver Diversity, Recruitment, and Retention (DRR) Advisory Board, our proposed study design will provide both evidence-based recruitment tools and important information about the risk factors associated with loss to follow-up. We will also implement a model that addresses these issues in real-time to ensure the larger study's success. We will engage in structured interviews with patients who select to not engage in the primary study and those who fall at risk of dropping out. In addition, we propose to conduct secondary data analyses of the socio-economic and health care utilization factors that contribute to patients selecting and completing a clinical integrative medicine trial. Primary outcomes of this supplement study include the development of model recruitment and retention tools and an empirical understanding of the barriers and factors contributing to recruitment, loss to follow up and successful completion of a clinical trial such as primary HEAL study. This study will be among the first to carefully examine the nature of CIH clinical trial participants. These findings will be germane to the conceptualization and implementation of future integrative medicine trials and will have a broader utility for future clinical research seeking to recruit and retain more diverse participants.