Improving Diversity, Inclusion, and Retention in BackinAction/AcuOA

摘要 据估计，不到三分之一的临床试验在最初的范围内招募了他们的目标样本量 预测的时间范围，完成临床试验的研究参与者更有可能是男性， 更年轻，收入更高，受教育程度更高。对于服务不足和Black的临床试验， 土著和有色人种(BIPOC)社区，还有其他与维护相关的挑战 与参与者接触，他们的生活可能包括更多的短暂和实际障碍，如交通 障碍、缺乏儿童保育、相互竞争的优先事项等。此外，目前还没有已知的研究专门检查 改善招聘和留用的机制，更不用说进一步确保 病人样本，用于CIH的临床试验。对目前获得资助的UH3的改进包括开发和 利用招募和保留多样性(DRR)咨询委员会，其中包括既往有 中西医结合临床试验经验，具有中西医结合经验的临床医生， 具有最少的中西医结合经验。此外，本补编还增加了招聘和留用 负责协调该咨询委员会并实施活动以实现其三个目标的专家。穿过 利用一名招聘和留住专家以及一名病人和照顾者多样性、招聘、 和保留(DRR)咨询委员会，我们建议的研究设计将提供基于证据的招聘 与遗失相关的风险因素的工具和重要信息，以供后续跟进。我们还将实施 一个实时解决这些问题的模型，以确保更大规模研究的成功。我们将致力于 对选择不参与主要研究的患者和那些陷入 退学了。此外，我们建议对社会经济和健康状况进行二级数据分析。 有助于患者选择和完成临床综合医学试验的护理利用因素。 这项补充研究的主要成果包括开发模范招聘和留用工具 以及对招聘障碍和因素的经验性理解，缺乏跟进和 成功完成临床试验，如初级康复研究。这项研究将是第一批 仔细检查CIH临床试验参与者的性质。这些发现将与 未来综合医学试验的概念化和实施，将对 未来的临床研究寻求招募和留住更多不同的参与者。

SUMMARY It is estimated that less than one-third of clinical trials recruit their target sample size within the originally predicted time frame and that research participants who complete a clinical trial are more likely to be male, younger, have higher incomes, and be more educated. For clinical trials working with underserved and Black, Indigenous, and People of Color (BIPOC) communities, there are additional challenges tied to maintaining contact with participants whose lives may include more transience and practical barriers such as transportation barriers, lack of childcare, competing priorities, etc. Further no study known has specifically examined mechanisms for improving recruitment and retention, let alone a process that further assures diversity in the patient sample, for clinical trials of CIH. Enhancement to the current funded UH3 include the development and utilization of a diversity in recruitment and retention (DRR) advisory board that includes patients with previous integrative medicine clinical trial experience, clinicians with integrative medicine experience, and clinicians who have minimal integrative medicine experience. In addition this supplement adds a recruitment and retention specialist who will coordinate this advisory board and implement the activities to meet its three aims. Through the utilization of both a recruitment and retention specialist and a patient and caregiver Diversity, Recruitment, and Retention (DRR) Advisory Board, our proposed study design will provide both evidence-based recruitment tools and important information about the risk factors associated with loss to follow-up. We will also implement a model that addresses these issues in real-time to ensure the larger study's success. We will engage in structured interviews with patients who select to not engage in the primary study and those who fall at risk of dropping out. In addition, we propose to conduct secondary data analyses of the socio-economic and health care utilization factors that contribute to patients selecting and completing a clinical integrative medicine trial. Primary outcomes of this supplement study include the development of model recruitment and retention tools and an empirical understanding of the barriers and factors contributing to recruitment, loss to follow up and successful completion of a clinical trial such as primary HEAL study. This study will be among the first to carefully examine the nature of CIH clinical trial participants. These findings will be germane to the conceptualization and implementation of future integrative medicine trials and will have a broader utility for future clinical research seeking to recruit and retain more diverse participants.