Age of initiation of tobacco products among USA youth and young adults

项目摘要 卫生局局长2012年的报告提供的数据表明，吸烟的开始是在 成年考虑到现有的新的和正在出现的烟草产品， 美国青少年和年轻人烟草使用的开始、变化模式和相关因素 对当代烟草监管科学至关重要。我们将直接通知食品和药物管理局 美国食品和药物管理局（FDA）对所有烟草制品的烟草监管权力，以保护公众的健康. 该项目直接涉及FDA的研究优先领域，重点是了解知识， 态度和行为，有助于烟草产品（TP）的启动，TP启动的年龄，和因素 与起始年龄有关。我们的研究包括对前三波的前瞻性二次分析， 美国青少年（12-17岁）烟草与健康人口评估（PATH）研究， 基线时报告从未使用的年轻成人（18-24岁）。六个TP将被考虑：香烟，电子- 香烟，雪茄（即传统雪茄，小雪茄，过滤雪茄），水烟;无烟烟草，以及任何这些 TP。每个TP考虑了7个结局：首次报告或过去30天使用的年龄， 易于使用，年龄为已确定的使用者（即，经常使用），首次报告双/聚TP的年龄 使用，首次使用调味TP的年龄，以及曾经使用易燃物的年龄。在以下方面的知识存在差距： 首次报告7种结局中每一种结局的年龄。这 项目有三个目标。目标1：在12-17岁的青年中，在第一波中从未使用过TP， 前瞻性地估计他们开始TP的年龄，并确定与年龄相关的风险因素。 启动香烟和每一个NCTPs：电子烟，雪茄，水烟和无烟烟草。目的 2：与目标1相同，但在18-24岁的年轻人中，他们从未使用过第1波的TP。目标3： 在第1波从未使用过TP的12-24岁青年和年轻成年人中， 以及从第1波到第2波和第3波的TP发作随时间的转变，并确定风险因素 与这些轨迹和转变相关。我们计划探索社会人口学，人际关系， 内在的，社会的，和环境因素可能与不同的开始年龄有关。 TP。与FDA规定的研究重点一致，本项目侧重于我们对 知识和行为，以最好地预测开始的年龄。很少有研究可以用纵向研究来检验假设。 年轻人和年轻成年人的数据。该项目通过以下方式加强了烟草监管科学的证据 利用全国纵向研究扩大有关新兴烟草产品的证据，并采取 这是当代数据的优势，反映了不断变化的烟草产品格局。该项目涉及 RFA-OD-18-002。

PROJECT SUMMARY The Surgeon General's 2012 report provided data that the initiation of cigarette smoking begins before adulthood. Considering the new and emerging tobacco products available, estimating the age and onset of initiation, changing patterns of tobacco use and correlates of tobacco use among U.S. youth and young adults is paramount to informing contemporary tobacco regulatory science. We will directly inform the Food and Drug Administration (FDA) authority on tobacco regulation about all tobacco products to protect the public’s health. This project directly address the FDA's research priority areas that focus on understanding the knowledge, attitudes, and behaviors that contribute to tobacco product (TP) initiation, age of TP initiation, and factors associated with age of initiation. Our study involves a prospective secondary analysis of the first three waves of the Population Assessment of Tobacco and Health (PATH) study among U.S. youth (12-17 years old) and young adults (18-24 years old) who reported never use at baseline. Six TPs will be considered: cigarettes, e- cigarettes, cigars (i.e. traditional cigars, cigarillo, filtered cigars), hookah; smokeless tobacco, and any of these TPs. Seven outcomes are considered for each TP: age to first report ever or past 30-day use, age to become susceptible to use, age to be an established user (i.e. ever use fairly regularly), age to first report dual/poly TP use, age to first use flavored TP, and age of ever combustible use. There is a gap in the knowledge related to the age of first reporting of each one of the seven outcomes prospectively and with contemporary data. This project has three aims. Aim 1: Among youth ages 12-17 years old who are never users of TPs at wave 1, to estimate prospectively their age of initiation of TPs and to identify the risk factors associated with the age of initiation of cigarettes and each one of the NCTPs: e-cigarettes, cigars, hookah, and smokeless tobacco. Aim 2: same as aim 1 but among young adults ages 18-24 years old who are never users of TPs at wave 1. Aim 3: Among youth and young adults ages 12-24 who are never users of TPs at wave 1, to identify the trajectories and transitions in the onset of TPs across time, from wave 1 to waves 2 and 3, and to identify the risk factors associated with these trajectories and transitions. We plan to explore socio-demographic, interpersonal, intrapersonal, social, and environmental factors potentially associated with the age of initiation of the different TPs. Consistent with research priorities FDA has set forth, this project focuses on our understanding of the knowledge and behaviors to best predict age of initiation. Few studies can test hypotheses with longitudinal data that span youth and young adults. This project strengthens the evidence for tobacco regulatory science by expanding the evidence regarding emerging tobacco products, using a national longitudinal study, and taking advantage of contemporary data that reflects the evolving tobacco product landscape. This project addresses RFA-OD-18-002.