Age of initiation of tobacco products among USA youth and young adults

项目总结 卫生局局长2012年的报告提供的数据表明，吸烟开始于 成人期。考虑到现有的新出现的烟草产品，估计年龄和发病时间 美国青年和青壮年烟草使用的初始、变化模式及其相关因素 对于告知当代烟草监管科学是至关重要的。我们会直接通知食品药品监督管理局 美国食品和药物管理局(FDA)授权对所有烟草产品进行烟草监管，以保护公众的健康。 这个项目直接涉及FDA的研究优先领域，重点是了解知识， 影响烟草产品(TP)启动的态度和行为、TP启动的年龄和因素 与入门年龄有关的。我们的研究涉及对前三波 美国青少年(12-17岁)的烟草与健康人口评估(PATH)研究 报告从未使用过基线药物的年轻人(18-24岁)。将考虑六个TPS：香烟、电子烟- 香烟、雪茄(即传统雪茄、雪茄、过滤雪茄)、水烟、无烟烟草等 TPS。每个TP考虑了七个结果：首次报告的年龄或过去30天的使用年龄，成为 易使用、成为已确定用户的年龄(即经常使用)、首次报告双/多聚TP的年龄 使用、首次使用加味茶多酚的年龄和曾经使用过可燃物的年龄。在与…有关的知识方面存在差距 第一次报告七个结果中的每一个并使用当代数据的年龄。这 该项目有三个目标。目标1：在从未使用过TPS的12-17岁青少年中， 前瞻性地估计他们开始TPS的年龄，并确定与以下年龄相关的风险因素 香烟和每一种NCTP的启动：电子烟、雪茄、水烟和无烟烟草。目标 2：与目标1相同，但在18-24岁的年轻人中，他们从未在浪潮1中使用TPS。目标3： 在年轻人和12-24岁的年轻人中，他们从未在第一波中使用TPS，以确定轨迹 以及从第一波到第二波和第三波的TPS开始时间的转变，并确定风险因素 与这些轨迹和转变相关联。我们计划探索社会人口统计、人际关系、 个人内部、社会和环境因素可能与不同的 TPS。与FDA提出的研究优先事项一致，该项目侧重于我们对 知识和行为，以最好地预测入门年龄。很少有研究能用纵向检验假说 涵盖年轻人和年轻人的数据。该项目通过以下方式加强了烟草监管科学的证据 扩大关于新兴烟草产品的证据，使用全国性的纵向研究，并采取 利用反映不断发展的烟草产品格局的当代数据。本项目致力于 RFA-OD-18-002。

PROJECT SUMMARY The Surgeon General's 2012 report provided data that the initiation of cigarette smoking begins before adulthood. Considering the new and emerging tobacco products available, estimating the age and onset of initiation, changing patterns of tobacco use and correlates of tobacco use among U.S. youth and young adults is paramount to informing contemporary tobacco regulatory science. We will directly inform the Food and Drug Administration (FDA) authority on tobacco regulation about all tobacco products to protect the public’s health. This project directly address the FDA's research priority areas that focus on understanding the knowledge, attitudes, and behaviors that contribute to tobacco product (TP) initiation, age of TP initiation, and factors associated with age of initiation. Our study involves a prospective secondary analysis of the first three waves of the Population Assessment of Tobacco and Health (PATH) study among U.S. youth (12-17 years old) and young adults (18-24 years old) who reported never use at baseline. Six TPs will be considered: cigarettes, e- cigarettes, cigars (i.e. traditional cigars, cigarillo, filtered cigars), hookah; smokeless tobacco, and any of these TPs. Seven outcomes are considered for each TP: age to first report ever or past 30-day use, age to become susceptible to use, age to be an established user (i.e. ever use fairly regularly), age to first report dual/poly TP use, age to first use flavored TP, and age of ever combustible use. There is a gap in the knowledge related to the age of first reporting of each one of the seven outcomes prospectively and with contemporary data. This project has three aims. Aim 1: Among youth ages 12-17 years old who are never users of TPs at wave 1, to estimate prospectively their age of initiation of TPs and to identify the risk factors associated with the age of initiation of cigarettes and each one of the NCTPs: e-cigarettes, cigars, hookah, and smokeless tobacco. Aim 2: same as aim 1 but among young adults ages 18-24 years old who are never users of TPs at wave 1. Aim 3: Among youth and young adults ages 12-24 who are never users of TPs at wave 1, to identify the trajectories and transitions in the onset of TPs across time, from wave 1 to waves 2 and 3, and to identify the risk factors associated with these trajectories and transitions. We plan to explore socio-demographic, interpersonal, intrapersonal, social, and environmental factors potentially associated with the age of initiation of the different TPs. Consistent with research priorities FDA has set forth, this project focuses on our understanding of the knowledge and behaviors to best predict age of initiation. Few studies can test hypotheses with longitudinal data that span youth and young adults. This project strengthens the evidence for tobacco regulatory science by expanding the evidence regarding emerging tobacco products, using a national longitudinal study, and taking advantage of contemporary data that reflects the evolving tobacco product landscape. This project addresses RFA-OD-18-002.