The effect of e-cigarette and hookah use on the age of asthma onset in the USA

项目总结 对现有行为数据进行创新性分析，研究老年性痴呆的病因学和流行病学 过去30天电子烟和水烟使用者中的哮喘发作是对科学兴趣的反应 通过了解这些烟草产品对健康的短期和长期影响 美国的这项建议侧重于青少年和成年人哮喘的发病年龄。电子烟和 水烟现在是当前烟草市场的主要特征，它们有可能 以类似于香烟的方式损害使用者的健康。因此，估计哮喘的发病年龄 在从不吸烟的人中评估过去30天使用电子烟和水烟的效果是 最重要的是保护公众健康，教育公众，为食品和药物提供证据 管理局(FDA)。有关哮喘发病年龄较早的信息将量化并显示 这些烟草产品的潜在风险，有助于防止人们开始使用或激励 用户退出。此外，控制和治疗哮喘的最有效方法是及早发现 这种疾病。提供电子烟和水烟使用者哮喘发病年龄的信息可以 帮助向医生和医疗保健提供者提供适当年龄的必要信息 使用这些烟草产品的患者进行哮喘筛查的窗口。我们建议估计 使用第1-5波(以及在我们研究期间发布的任何后续波)的哮喘发病年龄 期间)的烟草与健康人口评估(PATH)研究。提出了两个目标： 目的1：估计12-75岁以上青年和成人哮喘的发病年龄，并 控制因素后探讨电子烟使用与哮喘发病年龄的关系 其他风险因素。目的2：估计12-75岁以上青年和成人哮喘的发病年龄 6岁，并探讨使用水烟与哮喘发病年龄之间的关系 控制其他风险因素。目标1和目标2的分析将在从不吸烟的人中进行 避免因使用香烟而引起的潜在混淆。在与…有关的知识方面存在差距 哮喘的发病年龄，特别是在电子烟和水烟使用者中。最有效的方法是 建立这些联系是通过纵向的、前瞻性的研究。很少有研究可以测试 关于烟草相关健康后果的纵向数据的假设，包括哮喘 美国青年和成年人的全国代表。该项目解决了以下关键需求 了解并指导为FDA、烟草产品中心和一般 向公众提供更多关于使用这些烟草产品以减少公众数量的影响的信息 美国的健康死亡人数。

PROJECT SUMMARY Innovative analysis of existing behavioral data to study the etiology and epidemiology of the age of asthma onset among past 30-day e-cigarette and hookah users is responsive to the scientific interest area on health effects by understanding the short and long-term effects of these tobacco products in the U.S. This proposal focuses on the age of asthma onset in youth and adults. E-cigarettes and hookah are now dominant features of the current tobacco marketplace, and they have the potential to harm the health of users in ways similar to cigarettes. Therefore, estimating the age of asthma onset to evaluate the effect of past 30-day e-cigarette and hookah use among never cigarette users is paramount to protect public health, educate the public, and provide evidence to the Food and Drug Administration (FDA). Information on an earlier age of asthma onset will quantify and display the potential risk of these tobacco products, which can help prevent people from initiating use or motivate users to quit. In addition, the most effective way to control and treat asthma is with early detection of the disease. Providing information on the age of asthma onset in e-cigarette and hookah users can help provide necessary information to physicians and health care providers on the appropriate age windows for asthma screening in patients who use these tobacco products. We propose to estimate the age asthma of onset using waves 1-5 (and any subsequent waves released during our study period) of the Population Assessment of Tobacco and Health (PATH) Study. Two aims are proposed: Aim 1: To estimate the age of asthma onset among youth and adults ages 12-75+ years old, and explore the association between e-cigarette use and the age of asthma onset after controlling for other risk factors. Aim 2: To estimate the age of asthma onset among youth and adults ages 12-75+ years old, and explore the association between hookah use and the age of asthma onset after controlling for other risk factors. Analyses for Aims 1 and 2 will be conducted among never cigarette users to avoid potential confounding from cigarette use. There is a gap in the knowledge related to the age of asthma onset, specifically among e-cigarette and hookah users. The most effective way to establish these associations is with longitudinal, prospective research. Few studies can test hypotheses with longitudinal data on tobacco-related health outcomes, including asthma that is nationally representative of U.S. youth and adults. This project addresses a critical need to understand and guide efforts to provide FDA, the Center for Tobacco Products, and the general public with more information on the effects of using these tobacco products to reduce their public health toll in the United States.