Growing the Genetics of Addiction Workforce with URM Faculty-Student Research Experiences

项目总结 杰克逊实验室(JAX)将提供独特的研究和培训经验，旨在鼓励 并帮助在生物医学和行为科学中代表性不足的团体的成员 或者在与成瘾相关的领域推进研究或科学相关的职业。长期目标是增加 能够使用尖端遗传学和基因组学技术研究的下一代科学家的多样性 上瘾。为了实现这一目标，实习生的招聘工作将针对提供重要服务的机构 代表不足的少数民族(URM)人口和教职员工，他们本身就是URM。这项培训计划 由两个组件组成。首先，学员将完成定制的虚拟指导课程 旨在传授哺乳动物的基本技能和知识，以及成瘾的系统遗传学。这个 虚拟课程将结合新派生的内容和从JAX的几个签名派生的材料 课程包括麦库西克人类和哺乳动物遗传学短期课程，以及关于 成瘾的遗传学，以及已建立的JAX在线教育模块，包括老鼠基础知识 遗传和复杂的特征。然后，课程参与者将被邀请与2名学员一起返回日本宇宙航空研究开发机构 (博士后、研究生或本科生)通过主办获得延长的暑期研究经验 贾克斯教员。教员培训团队将在JAX由项目导师主持，他们将在那里使用Jaxs 高级研究资源，用于学习增强其对成瘾相关研究所需的技术 通过将哺乳动物遗传学和基因组学结合在一起，研究了一些现象。他们将回到自己的家 拥有知识、技能、数据和资源以支持后续研究、演示文稿、出版物的机构 并批准申请。这一模式将促进URM教师的职业发展，以及 参与的青年科学家实习生和大学管理学院未来的实习生。该计划是 旨在实现以下具体目标：1)提供哺乳动物遗传学和 通过虚拟的、有指导的指导来研究成瘾的系统遗传学。2)吸引不同的教职员工和学生团队 今年夏天，他们利用成瘾遗传学的先进方法和资源指导研究项目。3) 从代表不足的少数族裔群体中招募个人参加虚拟课程，指导研究 经验，以及职业发展技能培训。影响：成功完成这些目标将导致 更多来自URM组织的成瘾研究人员正在积极研究模型生物 遗传学和基因组学，以了解和表征成瘾相关行为的机制。教育性 材料将被广泛提供，一组精选的调查人员将推进开发具体的 基因和基因组研究方案，支持在这些领域使用新兴技术。这个 将对这一新计划的有效性进行评估，如果成功，可能会被用作扩展的模式 在其他研究领域或机构的部署。

PROJECT SUMMARY The Jackson Laboratory (JAX) will provide a unique research and training experience designed to encourage and assist members of groups that are under-represented in the biomedical and behavioral sciences to pursue or advance research or science-related careers in addiction-related areas. The long-term goal is to increase the diversity of next-generation scientists that can use cutting edge genetics and genomics techniques to study addiction. To achieve this goal, trainee recruitment efforts will target institutions serving significant underrepresented minority (URM) populations and faculty who themselves are URM. This training program consist of two components. To begin, participants will first complete a customized, virtual mentored course designed to deliver foundational skills and knowledge in mammalian and systems genetics of addiction. The virtual course will combine newly-derived content combined with material derived from several of JAX's signature courses including the McKusick Human and Mammalian Genetics Short Course, and the Short Course on the Genetics of Addiction, and from established JAX online educational modules including The Basics of Mouse Genetics, and Complex Traits. Then, a subset of course participants will be invited to return to JAX with 2 trainees (post-doctoral, graduate or undergraduate) for an extended summer research experience mentored by hosting JAX faculty. Faculty-trainee teams will be hosted at JAX by program mentors, where they will make use of JAXs advanced research resources to learn techniques needed to augment their research into addiction related phenomena through the incorporation of mammalian genetics and genomics. They will return to their home institutions with knowledge, skills, data and resources to support follow-on research, presentations, publications and grant applications. This model will foster the career development of URM faculty as well as both the participating young scientist-trainees and the future trainees of the URM faculty member. The program is designed to achieve the following Specific Aims: 1) Provide foundational education in mammalian genetics and systems genetics of addiction through virtual, mentored instruction. 2) Engage diverse faculty and student teams in summer mentored research projects utilizing advanced methods and resources for addiction genetics. 3) Recruit individuals from underrepresented minority groups to participate in the virtual course, mentored research experiences, and career development skills training. Impact: Successful completion of these aims will result in an expanded number of addiction researchers from URM groups who are actively working with model organism genetics and genomics to understand and characterize mechanisms of addiction related behavior. Educational materials will be made broadly available, and a select group of investigators will advance to develop specific genetic and genomic research programs with support in the use of emerging technologies in these fields. The effectiveness of this novel program will be evaluated and if successful, may be used as a model for expanded deployment in other research fields or institutions.