Growing the Genetics of Addiction Workforce with URM Faculty-Student Research Experiences

项目摘要 杰克逊实验室（JAX）将提供独特的研究和培训经验，旨在鼓励 并协助在生物医学和行为科学领域代表性不足的团体成员， 或在成瘾相关领域推进研究或与科学相关的职业。长期目标是增加 下一代科学家的多样性，可以使用尖端的遗传学和基因组学技术来研究 成瘾为实现这一目标，培训生招聘工作将针对服务于重要 代表性不足的少数民族（URM）人口和教师谁自己是URM。这个培训项目 由两部分组成。开始时，参与者将首先完成定制的虚拟辅导课程 旨在提供基本的技能和知识，在哺乳动物和系统遗传学的成瘾。的 虚拟课程将结合联合收割机新衍生的内容和来自几个JAX签名的材料 课程，包括McKusick人类和哺乳动物遗传学短期课程，以及短期课程， 成瘾遗传学，以及来自已建立的JAX在线教育模块，包括The Basics of Mouse 遗传学和复杂性状。然后，一部分课程参与者将被邀请与2名学员一起返回JAX （博士后，研究生或本科生）通过托管指导延长夏季研究经验 JAX教师学院学员团队将在JAX由项目导师主持，在那里他们将使用JAXs 先进的研究资源，以学习技术，需要增加他们的研究成瘾相关 通过哺乳动物遗传学和基因组学的结合，他们会回到自己的家 拥有知识、技能、数据和资源的机构，以支持后续研究、演讲、出版物 和补助金申请。这种模式将促进URM教师的职业发展， 参与的年轻科学家学员和URM教员的未来学员。该计划是 旨在实现以下具体目标：1）提供哺乳动物遗传学基础教育， 通过虚拟的、有指导的指导，2)吸引多元化的教师和学生团队 在夏季指导研究项目利用先进的方法和资源成瘾遗传学。第三章 从代表性不足的少数群体中招募个人参加虚拟课程，指导研究 经验和职业发展技能培训。影响：成功完成这些目标将导致 来自URM小组的更多成瘾研究人员正在积极研究模式生物， 遗传学和基因组学，以了解和表征成瘾相关行为的机制。教育 材料将广泛提供，一组经过挑选的调查人员将提前制定具体的 遗传和基因组研究计划，支持在这些领域使用新兴技术。的 这项新计划的有效性将进行评估，如果成功，可作为扩大的模式， 在其他研究领域或机构部署。

PROJECT SUMMARY The Jackson Laboratory (JAX) will provide a unique research and training experience designed to encourage and assist members of groups that are under-represented in the biomedical and behavioral sciences to pursue or advance research or science-related careers in addiction-related areas. The long-term goal is to increase the diversity of next-generation scientists that can use cutting edge genetics and genomics techniques to study addiction. To achieve this goal, trainee recruitment efforts will target institutions serving significant underrepresented minority (URM) populations and faculty who themselves are URM. This training program consist of two components. To begin, participants will first complete a customized, virtual mentored course designed to deliver foundational skills and knowledge in mammalian and systems genetics of addiction. The virtual course will combine newly-derived content combined with material derived from several of JAX's signature courses including the McKusick Human and Mammalian Genetics Short Course, and the Short Course on the Genetics of Addiction, and from established JAX online educational modules including The Basics of Mouse Genetics, and Complex Traits. Then, a subset of course participants will be invited to return to JAX with 2 trainees (post-doctoral, graduate or undergraduate) for an extended summer research experience mentored by hosting JAX faculty. Faculty-trainee teams will be hosted at JAX by program mentors, where they will make use of JAXs advanced research resources to learn techniques needed to augment their research into addiction related phenomena through the incorporation of mammalian genetics and genomics. They will return to their home institutions with knowledge, skills, data and resources to support follow-on research, presentations, publications and grant applications. This model will foster the career development of URM faculty as well as both the participating young scientist-trainees and the future trainees of the URM faculty member. The program is designed to achieve the following Specific Aims: 1) Provide foundational education in mammalian genetics and systems genetics of addiction through virtual, mentored instruction. 2) Engage diverse faculty and student teams in summer mentored research projects utilizing advanced methods and resources for addiction genetics. 3) Recruit individuals from underrepresented minority groups to participate in the virtual course, mentored research experiences, and career development skills training. Impact: Successful completion of these aims will result in an expanded number of addiction researchers from URM groups who are actively working with model organism genetics and genomics to understand and characterize mechanisms of addiction related behavior. Educational materials will be made broadly available, and a select group of investigators will advance to develop specific genetic and genomic research programs with support in the use of emerging technologies in these fields. The effectiveness of this novel program will be evaluated and if successful, may be used as a model for expanded deployment in other research fields or institutions.