Family Health Histories: Creating a culturally tailored tool to reduce health disparities in the African American Community

家庭健康史：创建适合文化的工具来减少非裔美国人社区的健康差异

• 批准号: 10400680
• 负责人: Kent Darnell Key
• 金额: $ 12.46万
• 依托单位: MICHIGAN STATE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-05-01 至 2026-01-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10400680
• 关键词: Address; African American; African American population; Area; Bacteria; Behavior; Biometry; Cardiovascular Diseases; Cessation of life; Collaborations; Communication; Communities; Conceptions; Confidence Intervals; Conscious; Data; Data Analyses; Development; Diabetes Mellitus; Early Diagnosis; Ensure; Event; Failure; Family; Family health status; Focus Groups; Foundations; Funding; Genealogy; General Population; Generations; Genetic; Genomics; Goals; Grant; HIV/STD; Health; Health Disparities Research; Health Personnel; Health Services Needs; Heart Diseases; Hypertension; Individual; Inherited; Intervention; K-Series Research Career Programs; Knowledge; Lead; Length; Link; Malignant Neoplasms; Measures; Mentors; Methods; Mission; Modeling; Morbidity - disease rate; National Institute on Minority Health and Health Disparities; Onset of illness; Outcome; Participant; Persons; Phase; Pilot Projects; Population; Positioning Attribute; Prevention; Preventive measure; Preventive screening; Primary Care Physician; Randomized; Recording of previous events; Reduce health disparities; Research; Research Design; Research Personnel; Sampling; Solid; Strategic Planning; Stroke; Testing; Training; Translational Research; Water; Work; Writing; acceptability and feasibility; career development; community based participatory research; community engaged research; design; early screening; ethnic health disparity; evidence base; experience; family structure; health communication; health disparity; health goals; health literacy; improve minority health; improved; interest; lead exposure; member; minority communities; mortality; pilot trial; preference; prevent; racial and ethnic; racial health disparity; randomized trial; recruit; research and development; satisfaction; screening; therapy design; therapy development; tool; uptake

African Americans (AA) suffer disproportionately across most health disparities (HD). Preventative behaviors including screenings can inform proactive measures to address many HD which include: diabetes, heart disease, high blood pressure, stroke, HIV, STDs/STIs, cancer, and cardiovascular disease, most of which can be prevented.1-3 Evidence suggests that a lack of general health literacy (HL) and racially appropriate health communication strategies may contribute to the consistent high rates of health disparities in the AA community. Family Health Histories (FHH), which describe genetic and other familial contributions to health, have been identified as an effective tool for prevention and early detection and screenings. The underutilization of FHHs in AA communities negatively impacts screening and preventative measures that could prevent the onset of disease, illness and ultimately death.4 Although many FHH toolkits have been created to assist families in gathering FHH information, these tools typically are mostly focused for the general population and do not account for the cultural and ethnic nuances, communication preference and health literacy levels of the African American community.4 The failure to effectively engage AA in the creation and conception of culturally relevant FHH tools and activities to date likely contributes to their underutilization in this population. The objective of this K01 is to develop culturally appropriate FHH tools designed for broad understanding and uptake in AA communities. The central hypothesis of this proposal is that, using a community based participatory research (CBPR) approach, co-development of a culturally appropriate FHH toolkit will increase the utility and engagement of AA families in FHH activities; increase effective health communication within the family structure; and increase the health literacy of participants in a multifaceted effort to reduce and ultimately eliminate racial and ethnic health disparities. Flint is an ideal community in which to conduct this participatory research because the recent events of the Flint Water Crisis have created interest in genetics and FHH in the AA community as a result of community concern around the generational impacts of bacteria and lead exposure on health. Therefore, we will have partners within AA communities in Flint who will be motivated to partner with us to develop these tools for Flint and for other minority communities. This career development award is being submitted by Dr. Kent Key, a candidate with extensive experience in CBPR and a solid foundation in qualitative and health disparities research. To reach his long term goal of becoming an R01-funded researcher in CBPR to reduce health disparities by increasing health literacy and using effective health communication strategies to reduce and ultimately eliminate racial health disparities for African-American populations, this K01 will provide additional training in the following areas: (1) intervention development and design and conduct of randomized trials, (2) health communication models, (3) health literacy promotion, (4) CBPR approaches to Genomics and Genetics, (5) biostatistics, (6) grant-writing.

在大多数健康差距(HD)中，非裔美国人(AA)遭受的痛苦不成比例。预防性行为 包括筛查可以提供主动措施，以应对许多HD，包括：糖尿病、心脏病、 高血压、中风、艾滋病毒、性传播疾病/性传播疾病、癌症和心血管疾病，其中大多数可能是 预防1-3证据表明，缺乏普遍的健康素养(HL)和符合种族标准的健康 沟通策略可能导致再生障碍性贫血社区始终存在较高的健康差距。 家庭健康史(FHH)描述了遗传和其他家庭对健康的贡献，一直以来 被确定为预防和早期发现和筛查的有效工具。FHH在中国的利用不足 再生障碍性贫血社区对筛查和预防措施产生负面影响，这些措施可以防止 疾病，疾病和最终死亡。4尽管已经创建了许多FHH工具包来帮助家庭 收集FHH信息，这些工具通常主要针对普通人群，不考虑 关于非裔美国人的文化和种族细微差别、沟通偏好和健康素养水平 社区。4未能有效地让AA参与创建和构思与文化相关的FHH工具 而迄今为止的活动可能是导致这些活动在这一人群中未得到充分利用的原因。 K01的目标是开发适合文化的FHH工具，设计用于广泛理解 以及AA社区的吸毒率。这一提议的中心假设是，使用基于社区的 参与式研究(CBPR)方法，共同开发适合文化的FHH工具包将增加 AA家庭在FHH活动中的效用和参与度；增加家庭内有效的健康沟通 结构；提高参与者的健康素养，多方面努力减少并最终消除 种族和民族健康差距。弗林特是进行这种参与性研究的理想社区。 因为最近的弗林特水危机事件引起了人们对遗传学和AAFHH的兴趣 社区关注细菌和铅暴露对世代的影响 健康。因此，我们将在弗林特的AA社区内拥有合作伙伴，他们将有动力与我们合作 为弗林特和其他少数族裔社区开发这些工具。 这个职业发展奖是由Kent Key博士提交的，他是一位有丰富经验的候选人 在CBPR方面，在质量和健康差距研究方面有坚实的基础。为了实现他的长期目标 成为CBPR中由R01资助的研究人员，通过提高健康素养和 使用有效的健康传播战略减少并最终消除种族健康差距 对于非洲裔美国人，K01将在以下方面提供额外的培训：(1)干预 开发、设计和进行随机试验，(2)健康传播模式，(3)健康素养 促进、(4)基因组学和遗传学的CBPR方法、(5)生物统计学、(6)赠款的撰写。