Dissecting pre- vs postsynaptic actin dynamics in synapse structure and strength

剖析突触结构和强度方面的突触前和突触后肌动蛋白动力学

• 批准号: 10404155
• 负责人: Aaron Donald Levy
• 金额: $ 2.77万
• 依托单位: UNIVERSITY OF MARYLAND BALTIMORE
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-07-02 至 2021-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10404155
• 关键词: 3-Dimensional; AMPA Receptors; Actins; Acute; Affect; Area; Biological; Biological Factors; Biology; Cells; Cellular biology; Complex; Data; Dendritic Spines; Disease; Electrophysiology (science); Future; Glutamate Receptor; Goals; Hippocampus (Brain); Image; In Vitro; Light; Long-Term Potentiation; Measures; Mediator of activation protein; Memory; Mental disorders; Microfilaments; Modeling; Molecular; Monomeric GTP-Binding Proteins; N-Methyl-D-Aspartate Receptors; Nanostructures; Neurons; Neurosciences; Optics; Positioning Attribute; Presynaptic Terminals; Probability; Process; Proteins; Reagent; Recombinant adeno-associated virus (rAAV); Regulation; Role; Science; Side; Structure; Synapses; Synaptic Vesicles; Testing; Time; Ultraviolet Rays; Vertebral column; Work; actin depolymerizing proteins; depolymerization; dimer; in vivo; insight; nanocluster; neurotransmitter release; optogenetics; polymerization; postsynaptic; presynaptic; receptor; receptor function; scaffold; spatiotemporal; tool; tool development; treatment strategy; vesicular release