Studies to Advance Recovery Supports (STARS) in Central Appalachia

阿巴拉契亚中部推进恢复支持研究 (STARS)

• 批准号: 10404116
• 负责人: Kimberly A Horn
• 金额: $ 51.54万
• 依托单位: EAST TENNESSEE STATE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-07-15 至 2025-04-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10404116
• 关键词: Achievement; Acute; Address; Advanced Development; Agreement; Algorithms; Appalachian Region; Assessment tool; Automobile Driving; Clinic; Clinical Trials; Communities; Consultations; Credentialing; Data; Data Analytics; Data Element; Development; Ecosystem; Education; Enrollment; FDA approved; Failure; Family; Fostering; Foundations; Geography; Goals; Guidelines; Health Services Accessibility; Health Services Research; Health system; Healthcare Systems; Horns; Individual; Infrastructure; Institution; Institutional Review Boards; Intervention Studies; Leadership; Mediating; Mentors; Methods; Mission; Modeling; National Institute of Drug Abuse; Opioid; Outcome; Pharmaceutical Preparations; Process; Protocols documentation; Public Health; Readiness; Recommendation; Recovery; Recovery Support; Registries; Research; Research Personnel; Research Priority; Research Training; Resources; Services; Site; Structure; Support System; Technology; Testing; Time; Training; Training Activity; Translations; Treatment outcome; Trust; Universities; Virginia; Work; career networking; certificate program; clinical research site; cohort; community center; data harmonization; data infrastructure; data sharing; design; experience; falls; improved; improved outcome; innovation; network models; novel; opioid epidemic; opioid use disorder; outreach; overdose death; patient oriented; patient population; peer; provider intervention; response; service intervention; sharing platform; success; support network; tool; trial design

PROJECT ABSTRACT Opioid use disorder and overdose deaths represent a national public health crisis that has been particularly acute in central Appalachia for decades. While treatment access and engagement are improving across Appalachia, the quality of the recovery support ecosystem is reflected in the small percentage of individuals who successfully maintain treatment with medications for opioid use disorder (MOUD) or abstain in recovery. An interface of community and treatment, peer recovery support services (PRSS) are a particularly high value proposition to enhance treatment outcomes and the recovery process, though one for which there is currently limited evidence to inform the content of their practice and use, particularly in the context of MOUD. While research to advance recovery support services is urgently needed in central Appalachia, insufficiencies in basic infrastructure, such as research capacity, engaged clinical research sites, and data infrastructure remain barriers to PRSS implementation and study. In response, the Studies To Advance Recovery Support (STARS) Network, a thematic, stakeholder-focused research network, will be initiated from an established regional research consortium—the Opioids Research Consortium of Central Appalachia (ORCCA). The following network aims will be executed by leveraging assets inherent to ORCCA and concentrating on PRSS for individuals treated in the context MOUD clinics: 1) build university and health system partner capacity to conduct community-engaged PRSS research; 2) enroll cohorts of MOUD clinics and PRSS professionals to foster commitment to engage in rapid conduct of PRSS studies; 3) advance processes and technologies to harmonize data and research efficiencies that advance PRSS studies across institutional partners; and 4) advance STARS network capacity to conduct rapid-cycle intervention research using rigorous designs. A dynamic team, jointly led by established ETSU and Virginia Tech researchers and facilitated by ORCCA institutions and PRSS partners with lived experience in recovery, offer assurance of successful execution. The proposed work is innovative because it aligns assets of an established opioids research consortium for maximum efficiency, demonstrates a novel application of the Recovery Ready Ecosystem Model, and creates rigorously developed assessment tools and critical cohort platforms of PRSS professionals and MOUD clinics for the purpose of recovery research. The proposed work is significant because the expected outcomes and products will mitigate current barriers to, and establish a foundation for, high-priority PRSS research in the central Appalachian region (KY, TN, VA, WV), a region devastated by the opioid crisis. Consistent with the NIDA mission, our long-term goal for this work is to inform the expansion of recovery support services, particularly PRSS, and advance recovery among individuals treated with MOUD.

项目摘要 阿片类药物使用障碍和过量死亡代表了一场全国性的公共卫生危机 几十年来，阿巴拉契亚中部急性。在治疗访问和参与方面正在改善 阿巴拉契亚 成功维持阿片类药物使用障碍（MOUD）或戒烟的药物治疗。 社区和治疗的接口，同行恢复支持服务（PRS）是一个特别高的价值 提高治疗结果和恢复过程的主张，尽管目前有一个 有限的证据来告知其实践和使用的内容，尤其是在Moud的背景下。尽管 阿巴拉契亚中部迫切需要进行促进恢复支持服务的研究， 基本基础设施，例如研究能力，参与临床研究站点和数据基础设施仍然存在 PRSS实施和研究的障碍。作为回应，提高恢复支持的研究（星星） 网络是一种主题，以利益相关者为中心的研究网络，将从既定地区启动 研究联盟 - 阿巴拉契亚中部（ORCCA）的阿片类药物研究联盟。下列 网络目标将通过利用对ORCCA的资产并专注于PRS来执行 在上下文中接受治疗的个人MOUD诊所：1）建立大学和卫生系统合作伙伴的能力 进行社区参与的PRSS研究； 2）注册MOUD诊所和PRS专业人员的队列 寄养致力于快速进行PRSS研究的承诺； 3）提前的过程和技术 协调数据和研究效率，以推进跨机构伙伴的PRSS研究；和4） 使用严格的设计进行快速循环干预研究的高级星际网络能力。一个 充满活力的团队，由ETSU和弗吉尼亚技术研究人员共同领导，由Orcca准备 机构和PRS与现场恢复经验合作，提供成功执行的保证。这 拟议的工作具有创新性，因为它与已建立的阿片类药物研究联盟的资产保持一致 最高效率，展示了恢复现成的生态系统模型的新颖应用，并创建 严格开发的评估工具和PRSS专业人士和MOUD诊所的关键队列平台 出于恢复研究的目的。拟议的工作很重要，因为预期的结果和 产品将减轻当前障碍，并为高优先级PRSS研究建立基础 阿巴拉契亚中部地区（KY，TN，VA，WV），一个被阿片类药物危机摧毁的地区。与 NIDA任务，我们的这项工作的长期目标是告知恢复支持服务的扩展， 特别是PRS，并提高接受MOUD治疗的人的康复。