Studies to Advance Recovery Supports (STARS) in Central Appalachia

阿巴拉契亚中部推进恢复支持研究 (STARS)

• 批准号: 10058570
• 负责人: Kimberly A Horn
• 金额: $ 55.15万
• 依托单位: EAST TENNESSEE STATE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-07-15 至 2025-04-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10058570
• 关键词: Achievement; Acute; Address; Advanced Development; Agreement; Algorithms; Appalachian Region; Assessment tool; Automobile Driving; Clinic; Clinical Trials; Communities; Consultations; Credentialing; Data; Data Analytics; Data Element; Development; Ecosystem; Education; Enrollment; FDA approved; Failure; Family; Fostering; Foundations; Geography; Goals; Guidelines; Health Services Accessibility; Health Services Research; Health system; Healthcare Systems; Horns; Individual; Infrastructure; Institution; Institutional Review Boards; Intervention Studies; Leadership; Mediating; Mentors; Methods; Mission; Modeling; National Institute of Drug Abuse; Opioid; Outcome; Pharmaceutical Preparations; Process; Protocols documentation; Public Health; Readiness; Recommendation; Recovery; Registries; Research; Research Personnel; Research Priority; Research Training; Resources; Services; Site; Structure; Support System; Technology; Testing; Time; Training; Training Activity; Translations; Treatment outcome; Trust; Universities; Virginia; Work; career networking; certificate program; clinical research site; cohort; community center; data harmonization; data infrastructure; data sharing; design; experience; falls; improved; improved outcome; innovation; network models; novel; opioid epidemic; opioid use disorder; outreach; overdose death; patient oriented; patient population; peer; prescription opioid; provider intervention; response; service intervention; sharing platform; success; support network; tool; trial design

PROJECT ABSTRACT Opioid use disorder and overdose deaths represent a national public health crisis that has been particularly acute in central Appalachia for decades. While treatment access and engagement are improving across Appalachia, the quality of the recovery support ecosystem is reflected in the small percentage of individuals who successfully maintain treatment with medications for opioid use disorder (MOUD) or abstain in recovery. An interface of community and treatment, peer recovery support services (PRSS) are a particularly high value proposition to enhance treatment outcomes and the recovery process, though one for which there is currently limited evidence to inform the content of their practice and use, particularly in the context of MOUD. While research to advance recovery support services is urgently needed in central Appalachia, insufficiencies in basic infrastructure, such as research capacity, engaged clinical research sites, and data infrastructure remain barriers to PRSS implementation and study. In response, the Studies To Advance Recovery Support (STARS) Network, a thematic, stakeholder-focused research network, will be initiated from an established regional research consortium—the Opioids Research Consortium of Central Appalachia (ORCCA). The following network aims will be executed by leveraging assets inherent to ORCCA and concentrating on PRSS for individuals treated in the context MOUD clinics: 1) build university and health system partner capacity to conduct community-engaged PRSS research; 2) enroll cohorts of MOUD clinics and PRSS professionals to foster commitment to engage in rapid conduct of PRSS studies; 3) advance processes and technologies to harmonize data and research efficiencies that advance PRSS studies across institutional partners; and 4) advance STARS network capacity to conduct rapid-cycle intervention research using rigorous designs. A dynamic team, jointly led by established ETSU and Virginia Tech researchers and facilitated by ORCCA institutions and PRSS partners with lived experience in recovery, offer assurance of successful execution. The proposed work is innovative because it aligns assets of an established opioids research consortium for maximum efficiency, demonstrates a novel application of the Recovery Ready Ecosystem Model, and creates rigorously developed assessment tools and critical cohort platforms of PRSS professionals and MOUD clinics for the purpose of recovery research. The proposed work is significant because the expected outcomes and products will mitigate current barriers to, and establish a foundation for, high-priority PRSS research in the central Appalachian region (KY, TN, VA, WV), a region devastated by the opioid crisis. Consistent with the NIDA mission, our long-term goal for this work is to inform the expansion of recovery support services, particularly PRSS, and advance recovery among individuals treated with MOUD.

项目摘要 阿片类药物使用障碍和过量死亡是一场全国性的公共卫生危机， 在阿巴拉契亚中部地区肆虐了几十年虽然治疗的可及性和参与度正在改善， 阿巴拉契亚，恢复支持生态系统的质量反映在个人的小百分比 成功维持阿片类药物使用障碍（MOUD）治疗或在恢复期弃权的患者。 作为社区和治疗的接口，同伴康复支持服务（PRSS）具有特别高的价值 建议，以加强治疗结果和恢复过程，虽然目前有一个 有限的证据来告知其实践和使用的内容，特别是在MOUD的背景下。而 在阿巴拉契亚中部，迫切需要进行研究，以促进恢复支持服务， 基本的基础设施，如研究能力、参与的临床研究站点和数据基础设施仍然存在 实施和研究PRSS的障碍。研究促进恢复支持（STARS） 该网络是一个专题性的、以知识产权持有者为重点的研究网络，将从一个已建立的区域网络发起， 阿帕拉契亚阿巴拉契亚中部阿片类药物研究联盟（ORCCA）。以下 网络目标将通过利用ORCCA固有的资产并集中于PRSS来实现， 在MOUD诊所接受治疗的个人：1）建立大学和卫生系统合作伙伴的能力， 进行社区参与的PRSS研究; 2）招募MOUD诊所和PRSS专业人员， 促进致力于快速开展PRSS研究; 3）推进流程和技术， 协调数据和研究效率，推动机构伙伴之间的PRSS研究;以及4） 提高STARS网络利用严格设计进行快速周期干预研究的能力。一 充满活力的团队，由ETSU和弗吉尼亚理工大学的研究人员共同领导，并由ORCCA提供协助 在恢复方面有实际经验的机构和减贫战略伙伴提供了成功执行的保证。的 拟议的工作是创新的，因为它调整了一个已建立的阿片类药物研究联盟的资产， 最大效率，展示了恢复就绪生态系统模型的新应用，并创建了 为PRSS专业人员和MOUD诊所严格开发评估工具和关键队列平台 用于恢复研究。拟议的工作意义重大，因为预期成果和 产品将减轻目前的障碍，并建立一个基础，高优先级的PRSS研究在 阿巴拉契亚中部地区（肯塔基州，田纳西州，弗吉尼亚州，西弗吉尼亚州），一个被阿片类药物危机摧毁的地区。符合 NIDA的使命，我们这项工作的长期目标是为恢复支持服务的扩展提供信息， 特别是PRSS，并在MOUD治疗的个体中促进康复。