Advanced Characterisation Methodologies to assess and predict the Health and Environmental Risks of Advanced Materials

用于评估和预测先进材料的健康和环境风险的先进表征方法

• 批准号: 10066165
• 金额: $ 39.09万
• 依托单位: UNIVERSITY OF BIRMINGHAM
• 依托单位国家: 英国
• 项目类别: EU-Funded
• 财政年份: 2022
• 资助国家: 英国
• 起止时间: 2022 至 无数据
• 项目状态: 未结题
• 来源: https://gtr.ukri.org/projects?ref=10066165
• 关键词: Advanced; Characterisation; Methodologies; assess; predict

MACRAMÉ’s Central Objective is to: • detect, characterise and quantify Advanced Materials during their processing and product-life cycle (incl. recycling/end-of-life) to assess (e.g. ecotox-/tox-test) the resulting impact on (human) health and the environment if/when they pose (intended or unintended) exposures to humans and/or the environment and to • advance (i.e. prepare for standardisation & harmonisation/’regulatory validation’) the wide-spread applicability and application of the developed test- and characterisation methods, by demonstrating their effectiveness and efficiency in the context of existing, market-relevant industrial materials, processes and products. In alignment with the EU strategies to secure the safety and sustainability of enabling and emerging technologies (incl. those based on chemicals and materials, as addressed in the EU’s Chemical Strategy for Sustainability (2020), and in the European Green Deal (2021)), the MACRAMÉ Project focusses on the development of methodologies that are applicable to ‘Advanced Materials (AdMas)’ - a categories that includes, but surpasses that of ‘nanomaterials’ (EU, ‘Definition of a Nanomaterial’), and that is aligned with the future oriented innovation, safety and sustainability considerations at the OECD (OECD (2020)), the EU (EU (2022)), and several of its Member States (e.g. Germany (2021)); this will be achieved by focussing the development and demonstration of novel methods and methodologies, as well as the advancement of their harmonisation and standardisation on (planned inhalable carbon-based AdMas in a variety of morphologies and dimensions, moving beyond spherical particles: (a) graphene-related material (GRM), (b) carbon fibres (CNTs), and (c) Poly Lactic-co-Glycolic Acid (PLGA). The focus on carbon-based AdMa is due to unsolved detection and characterisation issues especially in complex media

MACRAMITAL的主要目标是：·在加工和产品生命周期（包括产品生命周期）中检测、鉴定和量化先进材料。回收/报废）进行评估（例如生态毒性/毒性测试）如果/当它们构成（有意或无意）暴露于人类和/或环境，（即为标准化和协调/“监管验证”做准备）所开发的测试和表征方法的广泛适用性和应用，通过在现有的、与市场相关的工业材料、工艺和产品的背景下展示其有效性和效率。与欧盟战略保持一致，以确保使能和新兴技术的安全性和可持续性。如欧盟可持续发展化学战略（2020年）和欧洲绿色协议（2021年）所述，基于化学品和材料的方法，MACRAMTM项目侧重于开发适用于“先进材料（AdMas）”的方法，这一类别包括但超过了“纳米材料”（欧盟，“纳米材料的定义”），这与经合组织面向未来的创新，安全和可持续性考虑保持一致（OECD（2020））（欧盟（2022））及其几个成员国（例如，德国（2021年））;这将通过集中开发和示范新的方法和方法来实现，以及促进其协调和标准化，（计划中的可吸入碳基AdMas具有各种形态和尺寸，超越球形颗粒：（a）石墨烯相关材料（GRM），（B）碳纤维（CNT），和（c）聚乳酸-共-乙醇酸（PLGA）。对碳基AdMa的关注是由于未解决的检测和表征问题，特别是在复杂介质中