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Institutional Career Development Core

机构职业发展核心

基本信息

批准号：
10406153
负责人：
ELLEN L BURNHAM
金额：
$ 77.6万
依托单位：
UNIVERSITY OF COLORADO DENVER
依托单位国家：
美国
项目类别：
财政年份：
2018
资助国家：
美国
起止时间：
2018-05-01 至 2024-01-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10406153
关键词：
Address Applications Grants Award Biomedical Research Businesses Career Choice Clinical Clinical Investigator Award Clinical Research Clinical Sciences Clinical Trials Collaborations Colorado Competence Data Development Development Plans Dissemination and Implementation Educational Curriculum Entrepreneurship Environment Ethics Faculty Fostering Funding Goals Good Clinical Practice Grant Health Care Research Immersion Individual Industry Informatics Institutes Intellectual Property Journals Leadership Medicine Mentored Patient-Oriented Research Career Development Award Mentors Mentorship Modeling National Center for Advancing Translational Sciences Outcome Peer Review Phenotype Play Positioning Attribute Program Development Publications Research Research Methodology Research Personnel Research Training Role Science Scientist Secure Training Training Programs Translational Research Translations United States National Institutes of Health Universities base career career development community organizations diversity and inclusion education research ethnic diversity experience externship innovation medical schools next generation outreach programs racial diversity response responsible research conduct skill acquisition stem success synergism translational scientist

项目摘要

PROJECT SUMMARY/ABSTRACT Recent publications emphasize a shortfall in the number of investigators and scientists entering the clinical and translational research (CTR) pipeline. In response to the crisis, NCATS KL2 career development programs play an increasingly important role in preparing the next generation of clinical-translational scientists to be capable and resilient in the face of changes in health care, research funding and academic medicine. Our overall goal is to build upon the success of our CCTSI KL2 program and to provide in the next grant cycle a comprehensive Institutional Career Development Core KL2 training program, for 5 KL2 junior investigator scholar slots for 3 years each at 75% effort, that will foster outstanding and efficient clinical-translational research education, promote clinical-translational science competence and excellence, and augment the impact of research performed by KL2 scholars. To achieve our goals, we propose 3 Specific Aims that are congruent with our conceptual model of CTR persistence developed by our CCTSI colleagues: Aim 1: Optimize the provision of individualized competency-based training in translational research methodologies, clinical trials, and data informatics, along with ethical, regulatory and Good Clinical Practice principles. Aim 2: Prepare KL2 scholars to thrive in the new collaborative research environment by fostering skill development in entrepreneurship, team- based science and mentorship. Aim 3: Assure that KL2 scholars develop and submit competitive grant applications to transition to independent investigators. These specific aims will be achieved through the use of individualized career development plans to facilitate KL2 scholar oversight and guidance by KL2 program leadership in completing milestones and goals. KL2 scholars along with their mentors, as a dyad, will complete the yearlong CO-Mentor program to solidify effective mentoring relationships. Immersion into CTR will involve meaningful CTR research experiences with the scholar's mentors to support the transition to independence. Innovative experiences, in the form of externships with community organizations and businesses/industry will be provided. Career development initiatives will be offered in team science, entrepreneurship, data informatics and translation through dissemination and implementation. All scholars will complete training in the responsible conduct of research and Good Clinical Practice. KL2 program leadership will be engaged in several activities to increase diversity including partnering with the School of Medicine's Office of Diversity and Inclusion and the University's Office of Inclusion and Outreach. All KL2 scholars will participate in the KL2 Curriculum, and many of the programs will be available to other junior faculty with NIH K or equivalent awards, enhancing CTR research training and collaboration across the CCTSI and the University. Key outcomes for the KL2 program will be the success rate of KL2 scholars in remaining in CTR positions, securing grants (transition to R and U type awards), number of peer-reviewed publications in high impact journals, development of intellectual property and racial and ethnic diversity.

项目总结/摘要最近的出版物强调，进入临床研究的研究人员和科学家人数不足，翻译研究（CTR）管道。为了应对危机，NCATS KL 2职业发展计划发挥在培养下一代临床转化科学家方面发挥着越来越重要的作用，面对医疗保健、研究资金和学术医学的变化，我们的总体目标是以我们的CCTSI KL 2计划的成功为基础，并在下一个资助周期提供全面的机构职业发展核心KL 2培训计划，5个KL 2初级研究员奖学金名额，3个每年75%的努力，这将促进优秀和有效的临床转化研究教育，促进临床转化科学的能力和卓越，并扩大研究的影响由KL 2学者完成。为了实现我们的目标，我们提出了3个具体目标，这与我们的目标一致。 CTSI同事开发的CTR持久性概念模型：目标1：优化翻译研究方法、临床试验和数据方面的个性化能力培训信息学，沿着伦理、法规和良好临床实践原则。目标2：准备KL 2学者，在新的合作研究环境中茁壮成长，通过培养创业技能，团队，基于科学和导师制。目标3：确保KL 2学者制定并提交有竞争力的奖学金向独立调查员过渡的申请。这些具体目标将通过使用个性化的职业发展计划，以促进KL 2学者监督和KL 2计划的指导领导完成里程碑和目标。KL 2学者沿着他们的导师，作为一对，将完成为期一年的共同导师计划，以巩固有效的指导关系。沉浸在CTR中将涉及有意义的CTR研究经验与学者的导师，以支持过渡到独立。创新的经验，在与社区组织和企业/行业的externships的形式将是提供了职业发展计划将提供团队科学，创业，数据信息学和通过传播和实施进行翻译。所有学者将完成培训，研究和药物临床试验质量管理规范。KL 2计划领导层将参与多项活动，增加多样性，包括与医学院的多样性和包容性办公室和大学的包容和推广办公室。所有KL 2学者将参加KL 2课程，许多的项目将提供给其他拥有NIH K或同等奖项的初级教师，加强CTR研究在CCTSI和大学的培训和合作。KL 2计划的主要成果将是 KL 2学者继续担任CTR职位的成功率，获得赠款（过渡到R和U类型的奖励），在影响力大的期刊上发表经同行审查的出版物的数目，知识产权和种族平等的发展和种族多样性。