Institutional Career Development Core

机构职业发展核心

• 批准号: 9623478
• 负责人: ELLEN L BURNHAM
• 金额: $ 91.03万
• 依托单位: UNIVERSITY OF COLORADO DENVER
• 依托单位国家: 美国
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-05-01 至 2023-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9623478
• 关键词: Address; Applications Grants; Award; Biomedical Research; Businesses; Career Choice; Clinical; Clinical Investigator Award; Clinical Research; Clinical Sciences; Clinical Trials; Collaborations; Colorado; Competence; Data; Development; Development Plans; Educational Curriculum; Entrepreneurship; Environment; Ethics; Faculty; Fostering; Funding; Goals; Good Clinical Practice; Grant; Health Care Research; Immersion Investigative Technique; Individual; Industry; Informatics; Institutes; Intellectual Property; Journals; Leadership; Medicine; Mentored Patient-Oriented Research Career Development Award; Mentors; Mentorship; Modeling; Outcome; Peer Review; Phenotype; Play; Positioning Attribute; Program Development; Publications; Research; Research Methodology; Research Personnel; Research Training; Role; Science; Scientist; Secure; Training; Training Programs; Translational Research; Translations; United States National Institutes of Health; Universities; base; career; career development; community organizations; education research; ethnic diversity; experience; externship; innovation; medical schools; next generation; outreach; programs; racial diversity; response; responsible research conduct; skill acquisition; stem; success; synergism; translational scientist

PROJECT SUMMARY/ABSTRACT Recent publications emphasize a shortfall in the number of investigators and scientists entering the clinical and translational research (CTR) pipeline. In response to the crisis, NCATS KL2 career development programs play an increasingly important role in preparing the next generation of clinical-translational scientists to be capable and resilient in the face of changes in health care, research funding and academic medicine. Our overall goal is to build upon the success of our CCTSI KL2 program and to provide in the next grant cycle a comprehensive Institutional Career Development Core KL2 training program, for 5 KL2 junior investigator scholar slots for 3 years each at 75% effort, that will foster outstanding and efficient clinical-translational research education, promote clinical-translational science competence and excellence, and augment the impact of research performed by KL2 scholars. To achieve our goals, we propose 3 Specific Aims that are congruent with our conceptual model of CTR persistence developed by our CCTSI colleagues: Aim 1: Optimize the provision of individualized competency-based training in translational research methodologies, clinical trials, and data informatics, along with ethical, regulatory and Good Clinical Practice principles. Aim 2: Prepare KL2 scholars to thrive in the new collaborative research environment by fostering skill development in entrepreneurship, team- based science and mentorship. Aim 3: Assure that KL2 scholars develop and submit competitive grant applications to transition to independent investigators. These specific aims will be achieved through the use of individualized career development plans to facilitate KL2 scholar oversight and guidance by KL2 program leadership in completing milestones and goals. KL2 scholars along with their mentors, as a dyad, will complete the yearlong CO-Mentor program to solidify effective mentoring relationships. Immersion into CTR will involve meaningful CTR research experiences with the scholar's mentors to support the transition to independence. Innovative experiences, in the form of externships with community organizations and businesses/industry will be provided. Career development initiatives will be offered in team science, entrepreneurship, data informatics and translation through dissemination and implementation. All scholars will complete training in the responsible conduct of research and Good Clinical Practice. KL2 program leadership will be engaged in several activities to increase diversity including partnering with the School of Medicine's Office of Diversity and Inclusion and the University's Office of Inclusion and Outreach. All KL2 scholars will participate in the KL2 Curriculum, and many of the programs will be available to other junior faculty with NIH K or equivalent awards, enhancing CTR research training and collaboration across the CCTSI and the University. Key outcomes for the KL2 program will be the success rate of KL2 scholars in remaining in CTR positions, securing grants (transition to R and U type awards), number of peer-reviewed publications in high impact journals, development of intellectual property and racial and ethnic diversity.

项目摘要/摘要 最近的出版物强调进入临床和研究领域的研究人员和科学家的数量不足。 翻译研究(CTR)管道。为应对危机，NCATS KL2职业发展计划发挥作用 在培养下一代临床翻译科学家方面发挥越来越重要的作用 在面对医疗保健、研究经费和学术医学的变化时具有韧性。我们的总体目标是 在CCTSI KL2计划成功的基础上，在下一个赠款周期提供全面的 机构职业发展核心KL2培训计划，5个KL2初级调查员奖学金名额，3个 每年75%的努力，这将培养杰出而有效的临床-翻译研究教育， 促进临床翻译科学的能力和卓越，扩大研究的影响 由KL2学者执行。为了实现我们的目标，我们提出了三个与我们的目标一致的具体目标 CCTSI同事开发的CTR持久性概念模型：目标1：优化 在翻译研究方法、临床试验和数据方面进行基于能力的个性化培训 信息学，以及伦理、监管和良好的临床实践原则。目标2：准备KL2学者 在新的协作研究环境中，通过培养创业技能发展，团队- 以科学和指导为基础。目标3：确保KL2奖学金获得者制定并提交竞争性资助 申请过渡到独立调查人员。这些具体目标将通过使用 个性化的职业发展计划，以促进KL2计划对KL2学者的监督和指导 在完成里程碑和目标方面发挥领导作用。KL2学者和他们的导师，作为二人组，将完成 为期一年的共同导师计划，以巩固有效的指导关系。沉浸在CTR将涉及到 与这位学者的导师一起进行有意义的CTR研究，以支持向独立的过渡。 创新体验，以与社区组织和企业/行业的外部培训的形式 如果是这样的话。职业发展倡议将在团队科学、创业、数据信息学和 通过传播和实施进行翻译。所有学者都将完成培训中的负责人 进行研究和良好的临床实践。KL2计划领导将参与几项活动，以 增加多样性，包括与医学院的多样性和包容性办公室以及 大学包容和外展办公室。所有KL2学者将参加KL2课程，以及许多 将向其他拥有NIH K或同等奖项的初级教员提供课程，以加强CTR研究 CCTSI和大学之间的培训和协作。KL2计划的主要成果将是 KL2奖学金获得者留任CTR职位、获得资助(过渡到R和U型奖项)的成功率， 在影响较大的期刊、知识产权发展和种族问题上发表的同行评议出版物的数量 和种族多样性。