A digital intervention to prevent the initiation of opioid misuse in adolescents in school-based health centers

防止学校保健中心青少年滥用阿片类药物的数字干预措施

基本信息

批准号：
10408897
负责人：
Lynn Elizabeth Fiellin
金额：
$ 273.53万
依托单位：
YALE UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
2019
资助国家：
美国
起止时间：
2019-09-30 至 2023-10-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10408897
关键词：
19 year old Address Adolescence Adolescent Age Alcohols American Attention Attitude Behavioral Cause of Death Cellular Phone Centers for Disease Control and Prevention (U.S.)Cities Computer software Conflict (Psychology)Control Groups Country Data Decision Making Development Dose Effectiveness Enrollment Evaluation Female Adolescents Focus Groups Foundations Future Goals HIV Health Health Alliance Health Promotion Health behavior High Prevalence Human Resources Intervention Knowledge Life Male Adolescents Marijuana Methods National Institute of Drug Abuse Nature Opioid Outcome Overdose Participant Perception Pharmaceutical Preparations Phase Planning Theory Play Population Prevention Prevention program Randomized Controlled Trials Reporting Research Research Personnel Resources Risk Risk Behaviors Risk Factors Schools Self Efficacy Smoking Strategic Planning Technology Teenagers Testing Time Tobacco Translating Video Games Vulnerable Populations Work Youth aged base cost cost-effectiveness evaluation design digital intervention experience game development heroin use high risk high-risk adolescents implementation cost implementation framework implementation strategy improved improved outcome innovation intervention cost meetings mortality novel opioid misuse opioid mortality opioid overdose prescription opioid misuse prevent preventive intervention programs risk perception skills social learning social media substance use substance use prevention therapy design videogame intervention young adult

项目摘要

Most opioid misuse begins during adolescence and young adulthood. Adolescence is the time to intervene with prevention interventions in settings like school-based health centers (HCs), yet few exist that prevent initiation of opioid misuse. “Serious videogame” interventions can improve health behaviors. They meet adolescents “where they are,” and compared to standard interventions, they can reach large populations, with consistent fidelity, place limited demands on personnel/resources, facilitate rapid sustainable distribution, all at a potentially lower cost. This proposal harnesses the power of videogame interventions and incorporates components of effective substance use prevention programs to develop an evidence-informed intervention to prevent the initiation of opioid misuse in adolescents. Building on our experience developing videogame interventions and in partnership with the national School-Based Health Alliance (SBHA), we will develop and test a new videogame intervention, PlaySmart. PlaySmart will build upon our PlayForward videogame intervention platform that has demonstrated efficacy in improving attitudes and knowledge related to risk behaviors. Through rigorous formative work and with input from adolescents, and our SBHA and game development partners, we will create the PlaySmart videogame intervention. PlaySmart will be designed to provide players with behavioral skills and knowledge through repetitive and engaging videogame play to target adolescent perception of risk of harm from initiating opioid misuse. The specific aims of this proposal are to: 1) Phase 1 (UG3): Develop and pilot-test the PlaySmart game and, working with SBHA stakeholders, develop implementation strategies and partners; and 2) Phase 2 (UH3): Conduct a randomized controlled trial (RCT) with 532 high-risk 16-19 year old adolescents, in 10 local school-based (HCs), comparing the PlaySmart game to attention/time control games, and work with the SBHA to examine strategies for implementing PlaySmart in school-based HCs nationally. The main outcomes for the RCT will be the proportion of participants who report a perception of great risk of harm from misuse of opioids, intentions to misuse opioids, self-efficacy for refusing opioids, and initiation of opioid misuse. We hypothesize that participants in the PlaySmart group, compared to the control group, will have improved outcomes at 6 weeks (completion of gameplay), and at 3, 6 and 12 months. During the trial, we will collect implementation data from participants and school-based HCs and from the videogame software (e.g. dose). We will use an implementation framework to examine barriers and facilitators to implementing PlaySmart in school-based HCs nationally, and evaluate the cost-effectiveness of the intervention and the cost of the implementation strategies. This research, conducted by an experienced team of videogame intervention researchers and the national SBHA, holds the promise of creating an effective, engaging, and tailored intervention for preventing initiation of opioid misuse. This work has considerable potential for wide implementation, reach, and impact on high-risk adolescents through school-based HCs.

大多数阿片类药物滥用始于青春期和成年时期。青春期是时候干预在基于学校的医疗中心（HCS）等设置中进行的预防干预措施，但很少有阻止启动的设置 opioid滥用。 “严重的电子游戏”干预措施可以改善健康行为。他们遇到青少年 “它们在哪里”，并将其与标准干预措施进行比较，它们可以达到大量人群，并保持一致保真度，对人员/资源的需求有限，促进了快速的可持续分配可能较低的成本。该提案利用电子游戏干预的力量并纳入有效的药物使用预防计划的组成部分，以开发有证据的干预措施防止在青少年中滥用Ooid的倡议。以我们开发电子游戏的经验为基础干预措施并与国家学校卫生联盟（SBHA）合作，我们将发展和测试新的电子游戏干预措施，PlayMart。 PlaySmart将在我们的Playforward视频游戏上建立干预平台已证明在改善与会者和风险相关的知识方面效率行为。通过严格的形成性工作以及青少年的意见以及我们的SBHA和游戏开发合作伙伴，我们将创建PlayaySmart视频游戏干预。 PlaySmart将设计为通过重复和引人入胜的电子游戏播放为目标提供行为技能和知识青少年对造成阿片类药物滥用的伤害风险的看法。该提案的具体目的是： 1）阶段1（UG3）：开发和试点测试游戏玛特游戏，并与SBHA利益相关者合作实施策略和合作伙伴； 2）第2阶段（UH3）：进行随机对照试验（RCT）在10个本地学校（HCS）中，有532名高风险16-19岁的青少年，比较了玩具玛特游戏注意注意/时间控制游戏，并与SBHA合作检查实施PlaySmart的策略在全国范围内，以学校为基础的HCS。 RCT的主要结果将是报告的参与者的比例对滥用杀害骨类药物的危害风险的巨大风险，滥用opioids的意图，拒绝拒绝 opioids和Opioid滥用的倡议。我们假设戏剧组的参与者与对照组，将在6周（完成游戏完成）和3、6和12的情况下提高结果月份。在试验期间，我们将从参与者和学校的HCS收集实施数据以及电子游戏软件（例如剂量）。我们将使用实施框架来检查障碍和促进者在全国范围内在学校的HCS中实施Playsmart，并评估成本效益干预措施和实施策略的成本。这项研究，由经验丰富的视频游戏干预研究人员和国家SBHA团队拥有有效的，参与和量身定制的干预措施，以防止阿片类药物滥用。这项工作已经考虑通过基于学校的HCS对高风险青少年的广泛实施，触及和影响的潜力。

项目成果

期刊论文数量（2）

专著数量（0）

科研奖励数量（0）

会议论文数量（0）

专利数量（0）

A Video Game Intervention to Prevent Opioid Misuse Among Older Adolescents: Development and Preimplementation Study.

DOI：
10.2196/46912
发表时间：
2023-11-03
期刊：
JMIR SERIOUS GAMES
影响因子：
4
作者：
Aneni, Kammarauche;Fernandes, Claudia-Santi F.;Hoerner, Lily A.;Szapary, Claire;Boomer, Tyra M. Pendergrass;Fiellin, Lynn E.
通讯作者：
Fiellin, Lynn E.

A digital health game to prevent opioid misuse and promote mental health in adolescents in school-based health settings: Protocol for the PlaySmart game randomized controlled trial.