UCSC Graduate Program in Genome Sciences
UCSC 基因组科学研究生项目
基本信息
- 批准号:10410993
- 负责人:
- 金额:$ 31万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2022
- 资助国家:美国
- 起止时间:2022-07-01 至 2027-06-30
- 项目状态:未结题
- 来源:
- 关键词:
项目摘要
ABSTRACT
The UCSC Graduate Training Program in Genome Science combines cutting-edge computational biology
training in a multidisciplinary biomedical science and engineering environment. Among other strengths, UC
Santa Cruz is a world leader in computational biology, bioinformatics, genomic technologies and RNA biology.
The goals of the program are to prepare trainees for advanced academic and industry careers in biomedical
genomics. Our training program develops critical thinking skills, provides rigorous hands-on training in computer
science, statistics, and biological sciences, and develops scientific communication skills.
The proposed program will provide support for six trainees, each with a two-year appointment. Our trainee
applicant pool consists of PhD students who have already joined UCSC’s interdisciplinary genomics and
biomedical sciences community and completed three hands-on laboratory rotations during their first year of
study, at least one of which must be conducted in the laboratory of a GS Program faculty member.
Genome Science trainees participate in several innovative training activities. Each year, our trainees will
organize and run a bootcamp for each year’s incoming PhD cohort of students who are accepted by the Dept.
of Biomolecular Engineering. This 10-day activity is designed and implemented by the T32 trainees with
feedback and guidance from faculty. The centerpiece of the bootcamp is an ambitious hands-on activity for the
incoming grad cohort to tackle. Previous activities have included building a functional DropSeq single-cell RNA
sequencing machine (2017), as well as genome sequencing and assembly of the banana slug – UCSC’s mascot
(2019). Trainees receive training in labs of 26 faculty, including a winner of the MacArthur Award, members of
the National Academy of Sciences, and a Nobel Laureate. Formal coursework for trainees includes graduate-
level instruction in bioethics, programming, practical genomics, statistics, and scientific writing. These courses
cover essential topics in rigor and reproducibility and responsible conduct of research. Working with the Graduate
Advising Committee and their faculty mentors, trainees develop Individual Development Plans which may involve
further coursework to address specific deficiencies or special interests. In coordination with the NHGRI DAP
program, trainees will also serve as mentors to undergraduate students.
Program success will be assessed via several quantitative metrics of trainee productivity, such as the timing
and number of publications and success in applying for extramural research funds, as well as career outcomes
that are tracked following the award of PhDs. These metrics will be assessed by the Genome Sciences
Executive Committee.
The program is interdisciplinary, including 26 program faculty from 8 departments. Most trainees and
approximately half of program faculty are affiliated with the Biomolecular Engineering Department, as nearly all
BME faculty have genomics-focused research programs.
摘要
加州大学伯克利分校基因组科学研究生培训项目结合了尖端计算生物学
在多学科生物医学科学和工程环境中进行培训。在其他优势中,UC
圣克鲁斯在计算生物学、生物信息学、基因组技术和RNA生物学方面处于世界领先地位。
该计划的目标是为生物医学领域的高级学术和行业职业生涯做好准备。
基因组学。我们的培训计划发展批判性思维技能,提供严格的计算机动手培训
科学、统计和生物科学,并发展科学交流技能。
拟议的计划将为六名受训人员提供支持,每名受训人员的任期为两年。我们的实习生
申请者池由已经加入加州大学旧金山分校跨学科基因组学和
并在第一年完成了三次动手实验室轮换
研究,其中至少一项必须在GS计划教职员工的实验室中进行。
基因组科学实习生参加几个创新的培训活动。每年,我们的实习生都会
为每年被系录取的博士新生组织并举办训练营。
生物分子工程学。这项为期10天的活动由T32学员设计并实施,
教职员工的反馈和指导。训练营的中心是一项雄心勃勃的动手活动,
即将毕业的一批人要处理。之前的活动包括构建具有功能的DropSeq单细胞RNA
测序机(2017),以及香蕉鼻涕虫的基因组测序和组装-UCSC的吉祥物
(2019年)。学员在26名教职员工的实验室接受培训,其中包括一名麦克阿瑟奖获得者,
美国国家科学院和一位诺贝尔奖得主。学员的正式课程包括研究生课程-
生物伦理学、编程、实用基因组学、统计学和科学写作方面的水平指导。这些课程
涵盖研究的严谨性和重复性以及负责任的行为方面的基本主题。与毕业生一起工作
咨询委员会及其教师导师、实习生制定个人发展计划,可能包括
进一步的课程工作,以解决具体的缺陷或特殊兴趣。与NHGRI DAP协调
此外,受训者还将担任本科生的导师。
项目的成功将通过学员工作效率的几个量化指标进行评估,例如时间安排
出版物数量、申请校外研究基金的成功情况以及职业成就
在授予博士学位后进行跟踪。这些指标将由基因组科学公司进行评估
执行委员会。
该项目是跨学科的,包括来自8个系的26名项目教员。大多数实习生和
大约一半的程序教员隶属于生物分子工程系,因为几乎所有的
BME的教职员工有专注于基因组学的研究项目。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Angela Norie Brooks其他文献
Angela Norie Brooks的其他文献
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{{ truncateString('Angela Norie Brooks', 18)}}的其他基金
A novel approach to improve comprehensive profiling of the epigenome and epitranscriptome
改进表观基因组和表观转录组综合分析的新方法
- 批准号:
10434950 - 财政年份:2020
- 资助金额:
$ 31万 - 项目类别:
A novel approach to improve comprehensive profiling of the epigenome and epitranscriptome
改进表观基因组和表观转录组综合分析的新方法
- 批准号:
10650737 - 财政年份:2020
- 资助金额:
$ 31万 - 项目类别:
A novel approach to improve comprehensive profiling of the epigenome and epitranscriptome
改进表观基因组和表观转录组综合分析的新方法
- 批准号:
10029044 - 财政年份:2020
- 资助金额:
$ 31万 - 项目类别:
A novel approach to improve comprehensive profiling of the epigenome and epitranscriptome
改进表观基因组和表观转录组综合分析的新方法
- 批准号:
10241520 - 财政年份:2020
- 资助金额:
$ 31万 - 项目类别:
UCSC Research Mentoring Internship Program: An Initiative to Increase Diversity and Inclusion in Genomics Research
UCSC 研究指导实习计划:一项旨在提高基因组学研究多样性和包容性的举措
- 批准号:
10198970 - 财政年份:2013
- 资助金额:
$ 31万 - 项目类别:
UCSC Research Mentoring Internship Program: An Initiative to Increase Diversity and Inclusion in Genomics Research
UCSC 研究指导实习计划:一项旨在提高基因组学研究多样性和包容性的举措
- 批准号:
10555786 - 财政年份:2013
- 资助金额:
$ 31万 - 项目类别:
相似海外基金
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