Training in the Genome Sciences and the Hemoglobinopathies

基因组科学和血红蛋白病培训

• 批准号: 7640611
• 负责人: Huntington F Willard
• 金额: $ 19.91万
• 依托单位: DUKE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-05-01 至 2011-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7640611
• 关键词: Area; Awareness; Clinical; Collaborations; Computational Biology; Country; Development; Disease; Educational process of instructing; Environment; Equilibrium; Faculty; Funding; Future; Genome; Genomics; Goals; Group Meetings; Health; Hematology; Hemoglobinopathies; Individual; Institutes; Interdisciplinary Study; International; Journals; Laboratories; Link; Medical; Medicine; Mentors; Modeling; Nature; North Carolina; Pain; Postdoctoral Fellow; Proteomics; Research; Research Personnel; Research Project Grants; Research Training; Rotation; Science; Science Policy; Series; Sickle Cell; System; Tanzania; Thailand; Training; Training Programs; Transfusion; United States National Institutes of Health; Universities; Vascular Diseases; base; career; cohort; experience; meetings; member; multidisciplinary; post-doctoral training; programs; social; special interest group

DESCRIPTION (provided by applicant): The overall goal of the Duke University - University of North Carolina at Chapel Hill (UNC) Training Program in the Genome Sciences and the Hemoglobinopathies is to train a cohort of both domestic and foreign postdoctoral fellows to be outstanding investigators of the basis for and treatment of the hemoglobinopathies, using genomics and related large-scale and high-throughput approaches in the genome sciences. Whether each trainee's chosen area of focus is in genomics, proteomics or computational biology and whether one's future research is basic, translational or clinical, each fellow will be expected to gain a broad and comprehensive understanding of the genome sciences as applied to ongoing research projects in the hemoglobinopathies. Training towards this goal will be achieved through: advanced coursework; extensive rotations in genomics, proteomics, and computational laboratories; a weekly colloquium involving researchers in the genome sciences; research in laboratories with active programs in hemoglobinopathy research; and co-mentoring by training faculty with expertise both in the genome sciences and in the hemoglobinopathies in order to develop a full appreciation for the multidisciplinary nature of this training program. The training program will be directed jointly by the Director of the Duke Institute for Genome Sciences & Policy and by the Director of the Duke-UNC Comprehensive Sickle Cell Center. Outstanding fellows will be identified from among a strong pool of applicants to existing postdoctoral training opportunities at both Duke and UNC in hematology, transfusion medicine, medical genomics, vascular disease and the genome sciences; from applicants to individual mentors at Duke and UNC; and from applicants identified by an international advisory group consisting of colleagues and collaborators in Tanzania and Thailand. Research opportunities will be provided by a group of more than 25 Duke and UNC faculty members with expertise in the genome sciences and in the hemoglobinopathies. We will develop a group of domestic and foreign colleagues who are dedicated to advance our understanding and treatment of the hemoglobinopathies. This network of investigators will form the basis for an ongoing series of international collaborations to reduce the pain and burden of these disorders.

描述（由申请人提供）：杜克大学-北卡罗来纳大学教堂山分校（UNC）基因组科学和血红蛋白病培训项目的总体目标是培养一批国内外博士后研究员，利用基因组学和基因组科学中相关的大规模和高通量方法，成为血红蛋白病基础和治疗的杰出研究者。无论每位学员选择的重点领域是基因组学、蛋白质组学还是计算生物学，也无论未来的研究是基础研究、转化研究还是临床研究，每位学员都应该对基因组科学有广泛而全面的了解，并将其应用于正在进行的血红蛋白病研究项目。实现这一目标的培训将通过以下方式实现： 高级课程；在基因组学、蛋白质组学和计算实验室进行广泛的轮换；每周一次由基因组科学研究人员参加的座谈会；在血红蛋白病研究方面有活跃项目的实验室进行研究；并通过培训具有基因组科学和血红蛋白病专业知识的教师来共同指导，以便充分认识该培训计划的多学科性质。该培训计划将由杜克大学基因组科学与政策研究所所长和杜克大学-北卡罗来纳大学综合镰状细胞中心主任联合指导。将从杜克大学和北卡罗来纳大学现有的血液学、输血医学、医学基因组学、血管疾病和基因组科学博士后培训机会的强大申请者中挑选出优秀的研究员；从申请者到杜克大学和北卡罗来纳大学的个人导师；以及由坦桑尼亚和泰国的同事和合作者组成的国际咨询小组确定的申请人。研究机会将由超过 25 名杜克大学和北卡罗来纳大学教员提供，他们在基因组科学和血红蛋白病方面拥有专业知识。我们将培养一批致力于推进我们对血红蛋白病的理解和治疗的国内外同事。该研究人员网络将构成一系列正在进行的国际合作的基础，以减轻这些疾病的痛苦和负担。