Cellular and Molecular Biology at Michigan

项目摘要 此应用程序请求支持新的和重新设计的细胞和分子生物学博士项目 (CMB)在密歇根大学(UM)。CMB计划的使命是培养一批不同的科学家 在细胞和分子生物学方面进行负责任和严谨的研究，并做好准备 在生物医学科学的不同职业中取得成功。为了实现这一使命，中巴将使用循证证据 方法通过个性化和结构化的方法培训学生与学科相关的和可迁移的技能 基于能力的课程，在有效的指导实践中培训教师，并使用系统评估和 采取干预措施，不断改进其包容性培训做法。与纪律相关的培训包括 细胞生物学、生物化学、遗传学和数量生物学的基础课程和研讨会 通过每周的学生研讨会、学生组织的短期课程、年度研究接触到研究 研讨会和年度务虚会，通过严谨和可重复的研究深入了解一个领域 指导论文项目，以及基础和翻译领域广泛的体验式学习 生物医学科学。可转让技能培训的范围从以能力为基础的课程(如科学课程) 交流)到在方案和机构提供的体验式研讨会(例如关于领导力) 级别。关键的新元素包括1)能力映射到课程，重新关注可转移的技能 和专业发展，2)“严谨性和可重复性”培训的结构化要求， “负责任的研究行为”和科学交流，3)可指导的职业生涯行动计划 发展，4)增加对教师的导师培训，并为每个学生制定个性化的导师计划 作为要求，5)有意的多样性、公平和包容性(Dei)努力，以及6)增加形成性 程序设计的评估策略。招商银行得到了密歇根大学医学院的大力机构支持和 来自拉克姆研究生院以及参与该项目的各个部门。教员 该计划在科学上多样化，资金充足，该计划积极而成功地招募了一名 来自国家池的优秀和多样化的学生群体。约75%的学生通过雨伞加入 生物医学课程(PIBS，涵盖13个生物医学博士课程)，25%来自医学 科学家培训计划(MSTP)。在此申请中，我们要求每年支持16名学员，作为第82年 学生和8名三年级学生。现代生物医学科学已经变得越来越协作和团队- 基于，而且显然需要具有广泛学科操作知识的研究人员 同时拥有其专注学科的深厚专业知识。作为长期的跨学科合作 在4所学院的20个系之间，招商局处于独特的地位，通过培训新的 几代科学家合作解决细胞和分子生物学的基本问题 并制定创新的研究战略，将基础领域和翻译领域联系起来，以改善人类健康。

Project Summary This application requests support for the new and redesigned Cellular and Molecular Biology Ph.D. Program (CMB) at the University of Michigan (UM). The mission of the CMB program is to train a diverse group of scientists to conduct responsible and rigorous research in cellular and molecular biology and to prepare them to be successful in diverse careers in biomedical sciences. To pursue this mission, CMB will use evidence-based methods to train students in discipline-related and transferable skills via an individualized and structured competency-based curriculum, train faculty in effective mentoring practices, and use systematic evaluation and intervention to continuously improve its inclusive training practices. Discipline-related training includes foundational coursework and seminars in cell biology, biochemistry, genetics, and quantitative biology, broad exposure to research via weekly Student Seminars, student-organized Short Courses, an Annual Research Symposium, and an Annual Retreat, deep knowledge of an area via rigorous and reproducible research in mentored dissertation projects, and experiential learning in a wide range of areas in basic and translational biomedical sciences. Training in transferable skills range from competency-based courses (such as on scientific communication) to experiential workshops (such as on leadership) offered at the programmatic and institutional levels. Key new elements include 1) competency mapping to courses with a renewed focus on transferable skills and professional development, 2) structured requirements for training in “Rigor and Reproducibility”, “Responsible Conduct of Research”, and scientific communication, 3) a Guided Actionable Plan for career development, 4) the addition of mentor training for faculty and an individualized mentoring plan for each student as requirements, 5) intentional diversity, equity, and inclusion (DEI) efforts, and 6) the addition of formative evaluation strategies for programming. CMB has strong institutional support from the UM Medical School and from Rackham Graduate School, as well as from individual departments that participate in the program. Faculty in the program are scientifically diverse and well-funded, and the program actively and successfully recruits an outstanding and diverse group of students from a national pool. Approximately 75% students join via the umbrella Program in Biomedical Sciences (PIBS, covering 13 biomedical Ph.D. programs) and 25% from the Medical Scientist Training Program (MSTP). In this application, we request annual support for 16 trainees, as 8 2nd year students and 8 3rd year students. Modern biomedical science has become increasingly collaborative and team- based, and there is a clear need for researchers with an operational knowledge of a wide range of disciplines while holding deep expertise of their focused discipline. As a long-standing interdisciplinary collaboration between 20 departments across 4 colleges, CMB is uniquely positioned to fill this need by training new generations of scientists to collaboratively and address fundamental questions in cellular and molecular biology and generate innovative research strategies bridging basic and translational fields to improve human health.