Cellular and Molecular Biology at Michigan

项目摘要 此应用程序要求支持新的和重新设计的细胞和分子生物学博士学位。程序 (CMB)密歇根大学（UM）。CMB计划的使命是培养一批多样化的科学家 在细胞和分子生物学方面进行负责任和严格的研究，并为他们做好准备， 在生物医学科学的各种职业中取得成功。为了完成这一使命，CMB将使用基于证据的 通过个性化和结构化的方法来培养学生的学科相关和可转移的技能 以能力为基础的课程，培训教师有效的指导实践，并使用系统的评估和 采取干预措施，不断改进其包容性培训做法。与毒品有关的培训包括 细胞生物学、生物化学、遗传学和定量生物学的基础课程和研讨会 通过每周的学生研讨会，学生组织的短期课程，年度研究 研讨会和年度务虚会，通过严格和可重复的研究深入了解一个领域， 指导论文项目，并在基础和翻译的广泛领域的体验式学习 生物医学科学可转移技能的培训包括基于能力的课程（如科学知识课程）， 交流）的经验讲习班（如关于领导能力的讲习班） 程度.关键的新要素包括：1）将能力映射到课程，重新关注可转移技能 2）“严谨性和再现性”培训的结构化要求， “负责任的研究行为”和科学交流，3）职业生涯的指导性行动计划 发展，4）增加教师的导师培训和每个学生的个性化辅导计划 作为要求，5）有意的多样性，公平和包容（DEI）的努力，以及6）增加形成 方案拟订的评价战略。CMB拥有来自UM医学院的强大机构支持， 从拉克姆研究生院，以及从参与该计划的个别部门。教师 在该计划是科学多样性和资金充足，该计划积极和成功地招募了一个 来自全国的优秀和多样化的学生群体。大约75%的学生通过雨伞加入 生物医学科学计划（PIBS，涵盖13个生物医学博士学位。25%来自医疗机构 科学家培训方案。在此应用程序中，我们要求每年支持16名学员，作为8第二年 学生和8名三年级学生。现代生物医学科学已经变得越来越协作和团队- 的基础上，有一个明确的需要研究人员与广泛的学科的业务知识 同时在专业领域拥有深厚的专业知识。作为一个长期的跨学科合作 在4个学院的20个部门之间，CMB处于独特的地位，通过培训新的 几代科学家合作解决细胞和分子生物学的基本问题 并制定创新的研究战略，将基础和转化领域联系起来，以改善人类健康。

Project Summary This application requests support for the new and redesigned Cellular and Molecular Biology Ph.D. Program (CMB) at the University of Michigan (UM). The mission of the CMB program is to train a diverse group of scientists to conduct responsible and rigorous research in cellular and molecular biology and to prepare them to be successful in diverse careers in biomedical sciences. To pursue this mission, CMB will use evidence-based methods to train students in discipline-related and transferable skills via an individualized and structured competency-based curriculum, train faculty in effective mentoring practices, and use systematic evaluation and intervention to continuously improve its inclusive training practices. Discipline-related training includes foundational coursework and seminars in cell biology, biochemistry, genetics, and quantitative biology, broad exposure to research via weekly Student Seminars, student-organized Short Courses, an Annual Research Symposium, and an Annual Retreat, deep knowledge of an area via rigorous and reproducible research in mentored dissertation projects, and experiential learning in a wide range of areas in basic and translational biomedical sciences. Training in transferable skills range from competency-based courses (such as on scientific communication) to experiential workshops (such as on leadership) offered at the programmatic and institutional levels. Key new elements include 1) competency mapping to courses with a renewed focus on transferable skills and professional development, 2) structured requirements for training in “Rigor and Reproducibility”, “Responsible Conduct of Research”, and scientific communication, 3) a Guided Actionable Plan for career development, 4) the addition of mentor training for faculty and an individualized mentoring plan for each student as requirements, 5) intentional diversity, equity, and inclusion (DEI) efforts, and 6) the addition of formative evaluation strategies for programming. CMB has strong institutional support from the UM Medical School and from Rackham Graduate School, as well as from individual departments that participate in the program. Faculty in the program are scientifically diverse and well-funded, and the program actively and successfully recruits an outstanding and diverse group of students from a national pool. Approximately 75% students join via the umbrella Program in Biomedical Sciences (PIBS, covering 13 biomedical Ph.D. programs) and 25% from the Medical Scientist Training Program (MSTP). In this application, we request annual support for 16 trainees, as 8 2nd year students and 8 3rd year students. Modern biomedical science has become increasingly collaborative and team- based, and there is a clear need for researchers with an operational knowledge of a wide range of disciplines while holding deep expertise of their focused discipline. As a long-standing interdisciplinary collaboration between 20 departments across 4 colleges, CMB is uniquely positioned to fill this need by training new generations of scientists to collaboratively and address fundamental questions in cellular and molecular biology and generate innovative research strategies bridging basic and translational fields to improve human health.