Cellular and Molecular Biology at Michigan

项目概要/摘要： 细胞和分子生物学（CMB）博士该计划成立于大约四十年前， 在细胞和分子生物学的广泛领域协调学生的跨部门培训。中巴享有 来自拉克姆研究生院和医学院以及来自 教师的部门。计划教师是科学多样性和资金充足。培训机会范围 从大量领域的基础研究（结构生物学，生物化学，遗传学，分子生物学， 细胞生物学，发育，生理学和神经科学），以更多的翻译主题（癌症，代谢 疾病、免疫学、神经变性、衰老、微生物发病机理和干细胞生物学）。虽然 学生的个人论文项目的重点，该计划提供了接触到整个频谱， 通过每周的学生研讨会（CMB 850），学生组织的短期课程，年度研讨会， 研讨会/海报会议和年度务虚会。因此，该计划呼吁学生和教师谁 将受益于广泛接触到广泛的研究，在我们日益合作的不可或缺的 科学环境。该计划吸引了来自全国各地的优秀和多样化的学生群体。 大约75%的学生参加了生物医学科学项目（PIBS，一个14岁以下学生入学的保护伞）。 生物医学博士约25%来自医学科学家培训计划（MSTP）。的 课程，通常由PIBS/CMB学生在第二年中期完成，由MSTP/CMB完成 学生在第一年结束时，是灵活的，但包括生物化学，遗传学和细胞的核心领域 生物学以及包括定量训练的选修课程。在以下情况下实现无障碍 在第二年完成资格考试的基础上提出的建议，集中在学生的打算 research. CMB学生在竞争外部奖学金（NIH NRSA，NSF）方面非常成功， 参与支持科学推广和多样性的活动。目前有62名学生在 程序.在过去的5年里，74名学生参加了该计划，72名学生获得了博士学位。的 获得学位的平均时间约为5.6年，学生平均发表2篇第一作者论文， 4.2总数CMB博士毕业生继续从事学术研究和教学，商业研究， 制药业，生物技术和政府实验室，以及各种非研究，但科学- 相关职业。NIGMS T32培训补助金，这是一个竞争性的续期申请提供了关键 资源大部分PIBS/CMB学生在第二年获得培训补助金，部分学生在 他们的第三个; MSTP/CMB学生在他们的G2年有资格。无论是否得到资助，所有 中巴学生也有同样的要求。在这个应用程序中，我们要求每年16个插槽，第二年8个 学生和8个第三年（或G2年MSTP学生）。这是一个增加了1个插槽从什么是授予 最后一个周期（15，削减到14由扣押）。

Project Summary/Abstract: The Cellular and Molecular Biology (CMB) Ph.D. Program was founded approximately forty years ago to coordinate interdepartmental training of students in broad areas of cellular and molecular biology. CMB enjoys strong institutional support from Rackham Graduate School and the Medical School as well as from the faculty's departments. Program Faculty are scientifically diverse and well-funded. Training opportunities range from basic research in a large number of areas (structural biology, biochemistry, genetics, molecular biology, cellular biology, development, physiology and neuroscience), to more translational topics (cancer, metabolic disease, immunology, neuro-degeneration, aging, microbial pathogenesis and stem cell biology). Though students' individual dissertation projects are focused, the Program provides exposure to the entire spectrum of CMB research through the weekly student seminar (CMB 850), student-organized short courses, an Annual Symposium/Poster Session and an Annual Retreat. Thus, the Program appeals to students and faculty who will benefit from broad exposure to a wide range of research, indispensible in our increasingly collaborative scientific environment. The Program draws an outstanding and diverse group of students from a national pool. Approximately 75% join from the Program in Biomedical Sciences (PIBS, an umbrella for admission to 14 biomedical Ph.D. programs) and about 25% from the Medical Scientist Training Program (MSTP). The curriculum, typically completed by PIBS/CMB students by the middle of the second year and by MSTP/CMB students by the end of the first, is flexible, yet encompasses core areas of biochemistry, genetics and cell biology as well as elective coursework that includes quantitative training. Candidacy is achieved after completion of a qualifying exam in the second year based on a proposal that centers on the student's intended research. CMB students are highly successful at competing for external fellowships (NIH NRSA, NSF) and participate in activities that support scientific outreach and diversity. There are currently 62 students in the program. During the past 5 years, 74 students joined the program and 72 students received Ph.D.s. The average time to degree is approximately 5.6 years, with students publishing, on average, 2 first-author papers, 4.2 total. CMB Ph.D. graduates go on to careers in academic research and teaching, in commercial research in the pharmaceutical industry, biotech and government laboratories, as well in diverse non-research but science- related careers. The NIGMS T32 Training grant for which this is a competing renewal application provides key resources. Most PIBS/CMB students are supported by the training grant in their second year and some are in their third; MSTP/CMB students are eligible during their G2 year. Whether supported by the grant or not, all CMB students have the same requirements. In this application, we request 16 slots per year, 8 for 2nd year students and 8 for 3rd year (or G2 year MSTP students). This is an increase of 1 slot from what was awarded last cycle (15, cut to 14 by the sequester).