South Texas Doctoral Bridge Program

南德克萨斯博士桥梁课程

• 批准号: 10410462
• 负责人: BABATUNDE OLUKAYODE OYAJOBI
• 金额: $ 29.91万
• 依托单位: UNIVERSITY OF TEXAS HLTH SCIENCE CENTER
• 依托单位国家: 美国
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-09-13 至 2024-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10410462
• 关键词: Active Learning; Address; Admission activity; Award; Basic Science; Biochemistry; Bioinformatics; Biomedical Research; Budgets; Career Choice; Chemistry; Communication; Competence; Complement; Critical Thinking; Degree program; Development; Doctor of Medicine; Doctor of Philosophy; Doctor of Veterinary Medicine; Doctor' s Degree; Educational Curriculum; Educational workshop; Enrollment; Ethnic Origin; Experimental Designs; Faculty; Financial Support; Funding; Future; Genomics; Goals; Grant; Health; Health Sciences; Healthcare; Hispanic-serving Institution; Individual; Institution; Iowa; Laboratory Research; Link; Master' s Degree; Medicine; Mentors; Mentorship; Minority Groups; Monitor; National Institute of General Medical Sciences; North Carolina; Outcome; Positioning Attribute; Postdoctoral Fellow; Preparation; Productivity; Program Evaluation; Race; Readiness; Reproducibility; Research; Research Training; Schools; Science; Series; Social Interaction; Socioeconomic Status; South Texas; Student recruitment; Students; System; Talents; Texas; Time; Training; Training Programs; Underrepresented Populations; Underrepresented Students; Universities; Vision; Writing; base; bridge program; bridge to the doctorate; broadening participation research; career; cohort; college; curriculum development; design; doctoral student; education research; efficacy evaluation; experimental analysis; falls; graduate student; health disparity; improved; innovation; matriculation; peer coaching; programs; recruit; responsible research conduct; skills; stem; success; undergraduate student; underrepresented minority student

This renewal application stems from our successful first four years of a Bridge-to-the-Doctorate grant (South Texas Doctoral Bridge Program (STDBP; 2013-2017) supporting a partnership between the University of Texas Health Science Center at San Antonio (UT Health San Antonio; PhD-granting) and Texas State University – San Marcos (TxState, master's granting). The overarching goal of the STDBP is to increase the number of individuals from populations underrepresented (UR) in the biomedical sciences with quality education, research training, and mentorship that will position them to enter the best doctoral programs in the nation. Our program objectives are to recruit and train UR TxState students to complete a thesis-based M.S. degree and to prepare them not only to be competitive for acceptance into top-ranked biomedical doctoral programs, but also to be successful once they matriculate into those programs. During the prior 4 year project term, 22 M.S. graduate students received financial support from the STDBP grant award and have been trained in basic research by a cadre of highly motivated and talented participating faculty. Over 70% (10/14) of the Bridge Scholars who have exited the program bridged successfully to doctoral programs within two years of enrolling in the M.S. program. These include 8 Bridge Scholars who graduated with M.S. degrees and are currently enrolled in doctoral programs (7 Ph.D. and 1 D.V.M.) at outstanding research-intensive institutions including; UT Health San Antonio, Baylor College of Medicine, Duke University, Johns Hopkins University, University of North Carolina (UNC) at Chapel Hill, and Dartmouth College, amongst others as well as 2 Bridge Scholars who did not complete the master's degree because they elected to, and have transition directly to Ph.D. programs (UNC Chapel Hill and University of Iowa respectively) after their first year in the Bridge program. All STDBP alumni that have bridged continue to do well in their doctoral programs and several have since garnered merit-based awards since matriculating. One of the two Bridge Scholars who graduated with M.S. degrees but are yet to bridge, has stated plans to apply this fall to professional programs and the other is assessing career options. Eight Bridge Scholars remain in M.S. training (5 of who will also apply to Ph.D. programs this year for Fall 2018 entry) and two were terminated from the program early on for not meeting programmatic requirements with one of the latter still at TxState completing the requirements for the M.S. degree. Therefore excluding those dismissed from the program, overall, 10/12 Bridge Scholars (83%) seamlessly transitioned to doctoral studies without any time lapse. In this first cycle, the STDBP developed a new course focused on critical thinking, experimental design & analysis and responsible conduct of research to strengthen the curriculum at TxState. This course is now established and incorporated into the core curriculum for all M.S. (Bridge and non-Bridge) students in the Chemistry & Biochemistry department. Building on these accomplishments, our vision in this STDBP renewal is to further increase the number of UR students who graduate from TxState and successfully bridge to top-tier doctoral programs nationwide. To accomplish this, we will use a combination of: (i) enhancement of the TxState curriculum by development of new contemporary curriculum in “Genomics & Bioinformatics” and “Scientific Rigor & Reproducibility”; (ii) innovative and targeted developmental activities designed to prepare Bridge Scholars to continue to be competitive for admission to, and success at, top-tier doctoral programs; and (iii) refinements in student recruitment strategies and student tracking as well as mentor training. This competing renewal application seeks continued support again for 6 trainees each year for 5 years.

这一更新申请源于我们成功的第一个四年的桥梁到博士学位补助金（南 得克萨斯州博士桥梁计划（STDBP; 2013-2017）支持大学之间的伙伴关系， 位于圣安东尼奥的德克萨斯州健康科学中心（UT Health圣安东尼奥;授予博士学位）和德克萨斯州 大学----圣马科斯（TX State，授予硕士学位）。STDBP的首要目标是增加 在生物医学科学领域代表性不足（UR）的人的数量 教育，研究培训和导师，这将使他们进入最好的博士课程，在 民族我们的计划目标是招募和培训UR TxState学生完成基于论文的MS。 学位，并准备他们不仅是有竞争力的接受到一流的生物医学博士 计划，但也要成功，一旦他们录取到这些计划。在过去的四年里， 任期，22个硕士。研究生获得了STDBP助学金的财政支持，并已 在基础研究的高度积极性和人才参与教师的干部培训。超过70%（10/14） 的桥梁学者谁已经退出该计划的桥梁成功地在两个博士课程 在MS注册的几年程序.其中包括8名桥梁学者，他们毕业于M.S.度 目前正在攻读博士学位（7个博士学位）。和1个D.V.M.）在杰出的研究密集型 机构包括：UT Health圣安东尼奥、贝勒医学院、杜克大学、约翰霍普金斯大学 大学、北卡罗来纳州大学（查佩尔山）和达特茅斯学院等 作为2桥梁学者谁没有完成硕士学位，因为他们选择了，并有过渡 直接读博士计划（分别为查佩尔山和爱荷华州大学）后，他们的第一年， 桥梁计划。所有的STDBP校友，已经桥接继续做好他们的博士课程， 有几个学生自入学以来就获得了基于成绩的奖励。两位桥梁学者之一， 毕业于MS。学位，但尚未衔接，已表示计划申请今年秋天的专业课程 另一个是评估职业选择。八桥学者留在MS。培训（其中5人还将 申请博士学位今年秋季2018年入学的计划）和两个被提前终止的计划， 不符合计划要求，其中一个仍在TxState完成以下要求 的ms℃下因此，不包括那些被解雇的计划，总的来说，10/12桥梁学者 (83%）无缝过渡到博士研究，没有任何时间间隔。在第一个周期中，STDBP 开发了一个新的课程，重点是批判性思维，实验设计与分析和负责任的行为 研究，以加强在TxState课程。该课程现已设立并纳入 所有硕士的核心课程化学与生物化学系的（桥梁和非桥梁）学生。 在这些成就的基础上，我们在这次STDBP更新中的愿景是进一步增加UR的数量 从TxState毕业并成功衔接全国顶级博士课程的学生。到 为了实现这一目标，我们将使用以下组合：（一）通过开发 “基因组学和生物信息学”和“科学严谨性和生殖学”的新的当代课程; ㈡ 创新和有针对性的发展活动，旨在培养桥梁学者继续成为 有竞争力的录取，并在成功，顶级博士课程;及（iii）细化学生 招聘战略和学生跟踪以及导师培训。这种竞争性的续期申请 再次寻求继续支持，每年6名受训人员，为期5年。

项目成果

Suppression of telomere capping defects of Saccharomyces cerevisiae yku70 and yku80 mutants by telomerase.

• DOI: 10.1093/g3journal/jkab359
• 发表时间: 2021-12-08
• 期刊: G3 (Bethesda, Md.)
• 作者: Holland CL;Sanderson BA;Titus JK;Weis MF;Riojas AM;Malczewskyj E;Wasko BM;Lewis LK
• 通讯作者: Lewis LK

Development of Shortened miR-506-3p Mimics Exhibiting Strong Differentiation-Inducing Activity in Neuroblastoma Cells.

• DOI: 10.3390/molecules28176295
• 发表时间: 2023-08-28
• 期刊: Molecules (Basel, Switzerland)