FDA Vet-LIRN Site Application - Tier I Lab Renewal

项目摘要 密苏里州大学的兽医医学诊断实验室（VMDL）是一个完整的 服务诊断实验室，它是密苏里州唯一的实验室认可的美国 兽医实验室诊断师协会（AAVLD）。VMDL是一个一级实验室， 国家动物卫生实验室网络（NAHLN）。VMDL是一个一级实验室， 美国食品药品监督管理局（FDA）兽医实验室调查和回应 网络（Vet-LIRN）。VMDL为MU提供深入的实验室诊断支持 兽医保健中心医院、执业兽医、畜禽业、 伴侣动物健康的利益相关者，野生动物保护主义者，州和联邦 监管机构。本申请的目的是加强VMDL对FDA的支持 Vet-LIRN，关于“调查影响国家食品的潜在不良事件或 动物饲料供应，进行兽医产品，动物饲料或诊断测试 样品”。具体目标是：1）参与FDA Vet-LIRN样本分析，2）提供 支持潜在监管用途的分析数据，以及3）参与额外的FDA Vet-LIRN 研究和开发项目，如确定的方法开发和验证 由VPO申请的资金将使VMDL能够保持一级实验室的地位， 在此完成正在进行的FDA项目，开发新的方法， 常规诊断服务，更有效地应对食源性疾病的爆发。

PROJECT SUMMARY The Veterinary Medical Diagnostic Laboratory (VMDL) at the University of Missouri is a full service diagnostic laboratory and it is Missouri’s only laboratory accredited by the American Association of Veterinary Laboratory Diagnosticians (AAVLD). The VMDL is a Level I Lab of the National Animal Health Laboratory Network (NAHLN). The VMDL is a Tier I Laboratory of the Food and Drug Administration (FDA) Veterinary Laboratory Investigation and Response Network (Vet-LIRN). The VMDL provides in-depth laboratory diagnostic support to MU Veterinary Health Center Hospital, veterinary practitioners, livestock and poultry industry, stakeholders in companion animal health, wildlife conservationists, and state and federal regulatory agencies. The goal of this application is to strengthen the VMDL’s support of FDA Vet-LIRN, with respect to “investigate potential adverse events affecting the nation’s food or animal feed supply by conducting testing of veterinary products, animal feeds or diagnostic samples”. The specific aims are to 1) participate in FDA Vet-LIRN sample analysis, 2) provide analytical data to support potential regulatory use, and 3) participate in additional FDA Vet-LIRN research and development projects, such as method development and validation as determined by the VPO. The requested funding will enable the VMDL to maintain the Tier I Lab status, hereby completing the on-going FDA projects, developing new methods without interrupting routine diagnostic services, and more efficiently responding to foodborne disease outbreaks.