FDA Vet-LIRN Capacity-Building of Ohio ADDL to support bacterial identification of foodborne pathogens

点击翻译按钮获取中文摘要

This proposal from the Ohio Department of Agriculture (ODA) is in response to Funding Opportunity Announcement (FOA) PAR-18-604 from the Food and Drug Administration (FDA) Center for Veterinary Medicine (CVM) Veterinary Laboratory Investigation and Response Network (Vet-LIRN). This proposal from ODA’s Animal Disease Diagnostic Laboratory (ADDL) addresses the following key project areas: 1. Purchase of equipment needed to improve diagnostic capacity for Vet-LIRN case investigations of foodborne pathogens. a. We are requesting funds to support to the purchase of a Bruker MALDI Biotyper® Sirius RUO System for bacterial identification. 2. Conduct increased testing in response to a new need identified by the VPO. a. MALDI-TOF technology allows for high throughput identification of bacterial isolates to reduce turnaround time of bacterial culture and isolation. Additionally, participation in additional projects such as method development and/or method validation/improvement and matrix extension work as determined by the VPO may be included in the capacity-building funds. This proposal will maintain the capacity of our laboratory to conduct molecular diagnostic testing for high-throughput sample processing capability and data analysis by maintaining active service contracts to reduce any delays in testing due to equipment malfunctions or needed repairs.