National Dissemination of I-Corps@NCATS: Accelerating Translation through Commercialization

摘要。通过培训我们的转化科学工作人员，以更好地了解 他们的研究，I-Corps@NCATS计划的传播提供了前所未有的机会， 通过CTSA中心和网络系统加速科学翻译。I-Corps@NCATS计划 最初是根据CTSA《增强网络容量管理补充》（PA-16-328）开发的。 为期5周的I-Corps@NCATS短期课程是专门为满足生物医学的需要而设计的。 科学家在学术医疗中心，并已证明对科学翻译的重大影响， 通过商业化发现。从最初的9个I-Corps@NCATS 另外13个CTSA实习生地点的导师节点将提高CTSA的创新能力 联盟并创建转化科学国家创新网络。我们使用的是一种强大的火车- 培训员模式已证明在传播标准化课程和方法方面是有效的， 提高我们将生物医学研究推向商业产品的集体能力， 服务这种方法将扩大I-Corps@NCATS培训方案的范围和实施 为临床和翻译研究者，使他们可以更充分地参与商业化 从想法产生到临床应用的过程，并作为团队准备竞争SBIR/STTR， 其他国家计划。通过与22个CTSA合作伙伴合作，我们实现了无与伦比的临界质量， 创新者、专家、资源和公私合作伙伴关系，可以塑造和协调医疗保健 研究，促进商业化努力，并为创业兴趣提供焦点， 投资I-Corps@NCATS计划的传播将加速生物医学的翻译 通过建立I-Corps@NCATS网络能力，在不同发展阶段进行创新， 国家培训员培训方案（目标1）。我们将应用一套通用的指标，这些指标已经被 开发和测试，以评估I-Corps@NCATS计划的有效性和影响， 由22个CTSA中心组成的扩展网络（目标2）。我们将加速新发现向 通过在CTSA网络中进一步传播奠定基础，改善医疗保健服务， 发展转化科学国家创新网络（目标3）。通过传播一种方法， 证明了验证创新想法的商业潜力的有效性， 技术和连接潜在的合作者创造新的机会，我们的目标是有一个显着的 对科学发现转化为改善人类健康的影响。

ABSTRACT. By training our translational science workforce to better understand the commercial potential of their research, the dissemination of the I-Corps@NCATS program provides an unprecedented opportunity to accelerate scientific translation through the CTSA Hub and Network system. The I-Corps@NCATS program was initially developed with a CTSA Administrative Supplement to Enhance Network Capacity (PA-16-328). The 5-week I-Corps@NCATS short course was designed specifically to meet the needs of biomedical scientists in academic medical centers and has demonstrated significant impact on the translation of scientific discovery through commercialization. The dissemination of this program from the initial 9 I-Corps@NCATS Mentor Nodes to an additional 13 CTSA Trainee Sites will increase the innovative capacity of the CTSA Consortium and create a Translational Science National Innovation Network. We are using a robust Train-The- Trainer model that has proven effective at disseminating a standardized curriculum and approach aimed at improving our collective capacity for advancing biomedical research through to commercial products and services. This approach will expand the scope and implementation of the I-Corps@NCATS training program for clinical and translational investigators so that they may participate more fully in the commercialization process from idea generation to clinical application and be prepared as teams to compete for SBIR/STTRs and other NIH national programs. By working with 22 CTSA partners, we achieve an unparalleled critical mass of innovators, experts, resources and public-private partnerships, which can shape and coordinate healthcare research, facilitate commercialization efforts and provide a focal point for entrepreneurial interest and investment. The dissemination of the I-Corps@NCATS program will accelerate the translation of biomedical innovation across different stages of development by building the I-Corps@NCATS network capacity through a national Train-The-Trainer program (Aim 1). We will apply a set of common metrics, that have already been developed and tested, to evaluate the effectiveness and impact of the I-Corps@NCATS program across the expanded network of 22 CTSA Hubs (Aim 2). We will accelerate the transition of discoveries toward improved healthcare services by laying the foundation for further dissemination across the CTSA network and develop the Translational Science National Innovation Network (Aim 3). By disseminating an approach with demonstrated effectiveness for validating the commercial potential of innovative ideas, advancing early stage technologies and connecting potential collaborators to create new opportunities, we aim to have a significant impact on the translation of scientific discoveries to improved human health.