Core 001 - Virology Core
Core 001 - Virology Core
批准号:
10428298
负责人:
Mansun Law
金额:
$35.42万
依托单位国家:
美国
项目类别:
财政年份:
2022
资助国家:
美国
项目状态:
未结题
起止时间:
2022-02-01 至 2027-01-31
关键词:
AnimalsAntibodiesAntibody ResponseAntibody SpecificityAntibody titer measurementAntigensB-LymphocytesBiological AssayBlood specimenCell SurvivalCollectionComplexCost efficiencyDataDatabasesEnsureEnzyme-Linked Immunosorbent AssayFoundationsFreezingGlycoproteinsGoalsHepatitis C AntibodiesHepatitis C VaccineHepatitis C virusHumanImmunizeImmunology procedureInternationalLawsLeadLibrariesLiquid substanceMacacaMethodsMonitorMusNitrogenPeer ReviewPeripheral Blood Mononuclear CellPlasmaPlasmablastPrimatesProceduresProcessProgram Research Project GrantsProtocols documentationPublicationsQuality ControlReagentRecombinantsReproducibilityReproducibility of ResultsResearchResearch PersonnelResearch Project GrantsResourcesRunningSamplingShipsStandardizationStructureSystemTimeVaccine AntigenVaccine ResearchVirusWestern BlottingWorkdata qualitydesignexperimental studyimprovedmembermutantneutralizing antibodyprogramsresponsesynergismvaccine developmentvaccine trialvirology
中文摘要
项目总结
核心B病毒学将作为集中的研究资源,以促进本P01的研究目标
程序。核心B的功能包括(1)收集和开发丙型肝炎病毒研究试剂库和
维持他们对项目的供应;(2)进行标准化的丙型肝炎病毒抗原质量控制分析,
抗体滴度和病毒中和活性的测量,以确保一致性和重复性
实验结果;(3)为下游实验处理动物样本;(4)开发和记录
标准化的研究试剂和检测方法,以加快丙型肝炎病毒疫苗的开发。核心B病毒学将
提高P01计划研究项目和核心的成本效率、数据质量和协同效应。
英文摘要
PROJECT SUMMARY
Core B Virology will serve as a centralized research resources to facilitate the research objectives of this P01
program. The functions of Core B include (1) collect and develop a library of HCV research reagents and
maintain their supply for the program; (2) perform standardized assays for quality-control of HCV antigens,
measurement of antibody titers and virus neutralizing activities, to ensure consistent and reproducibility of
experimental results; (3) processing animal samples for downstream experiments; (4) develop and document
standardized research reagents and assays to accelerate HCV vaccine development. Core B Virology will
improve cost efficiency, data quality and synergy of the research projects and cores of the P01 program.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Broadly Effective HCV Vaccine
-
批准号:10557871
-
项目类别:
-
资助金额:$208.35万
-
财政年份:2022
-
负责人:Mansun Law
-
依托单位:
Understanding human antibody responses to chronic viral hepatitis C
-
批准号:10551237
-
项目类别:
-
资助金额:$62.18万
-
财政年份:2022
-
负责人:Mansun Law
-
依托单位:
Admin Core
-
批准号:10428297
-
项目类别:
-
资助金额:$8.61万
-
财政年份:2022
-
负责人:Mansun Law
-
依托单位:
Admin Core
-
批准号:10557872
-
项目类别:
-
资助金额:$11.66万
-
财政年份:2022
-
负责人:Mansun Law
-
依托单位:
Broadly Effective HCV Vaccine
-
批准号:10428296
-
项目类别:
-
资助金额:$210.29万
-
财政年份:2022
-
负责人:Mansun Law
-
依托单位:
Understanding human antibody responses to chronic viral hepatitis C
-
批准号:10435356
-
项目类别:
-
资助金额:$62.18万
-
财政年份:2022
-
负责人:Mansun Law
-
依托单位:
Core 001 - Virology Core
-
批准号:10557873
-
项目类别:
-
资助金额:$34.73万
-
财政年份:2022
-
负责人:Mansun Law
-
依托单位:
Rheumatoid factor and cryoglobulinemia in chronic viral infection
-
批准号:9896553
-
项目类别:
-
资助金额:$29.03万
-
财政年份:2019
-
负责人:Mansun Law
-
依托单位:
Cooperative Center for the study of HCV antibody responses and vaccine antigens
-
批准号:9248879
-
项目类别:
-
资助金额:$91.87万
-
财政年份:2016
-
负责人:Mansun Law
-
依托单位:
Administrative Core
-
批准号:9096639
-
项目类别:
-
资助金额:$27.86万
-
财政年份:2016
-
负责人:Mansun Law
-
依托单位:
Structure and function of Hepacivirus envelope glycoprotein
-
批准号:9084122
-
项目类别:
-
资助金额:$62.56万
-
财政年份:2016
-
负责人:Mansun Law
-
依托单位:
Cooperative Center for the study of HCV antibody responses and vaccine antigens
-
批准号:9903195
-
项目类别:
-
资助金额:$88.83万
-
财政年份:2016
-
负责人:Mansun Law
-
依托单位:
Antibody responses to HCV vaccine antigens in infection and vaccination
-
批准号:9096640
-
项目类别:
-
资助金额:$39.0万
-
财政年份:2016
-
负责人:Mansun Law
-
依托单位:
Dissecting virus neutralizing determinants to guide HCV vaccine development
-
批准号:9212766
-
项目类别:
-
资助金额:$45.71万
-
财政年份:2014
-
负责人:Mansun Law
-
依托单位:
Dissecting virus neutralizing determinants to guide HCV vaccine development
-
批准号:9017908
-
项目类别:
-
资助金额:$45.0万
-
财政年份:2014
-
负责人:Mansun Law
-
依托单位:
Dissecting virus neutralizing determinants to guide HCV vaccine development
-
批准号:8728397
-
项目类别:
-
资助金额:$79.27万
-
财政年份:2013
-
负责人:Mansun Law
-
依托单位:
Hepatitis C virus E2 glycoprotein
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批准号:7570115
-
项目类别:
-
资助金额:$28.49万
-
财政年份:2009
-
负责人:Mansun Law
-
依托单位:
Hepatitis C virus E2 glycoprotein
-
批准号:7847617
-
项目类别:
-
资助金额:$23.74万
-
财政年份:2009
-
负责人:Mansun Law
-
依托单位:
Discovery of potent human antibodies for prevention of (recurrent) HCV infection
-
批准号:7904000
-
项目类别:
-
资助金额:$46.9万
-
财政年份:2008
-
负责人:Mansun Law
-
依托单位:
Understanding human neutralizing antibodies to hepatitis C virus
-
批准号:9285691
-
项目类别:
-
资助金额:$55.6万
-
财政年份:2008
-
负责人:Mansun Law
-
依托单位:
海外基金