Let’s K-Talk: A Storytelling Intervention Leveraging Chatbot Technology to Prevent HPV and HPV Associated Cancers for Ethnic Koreans Living in the U.S.

Let’s K-Talk：利用聊天机器人技术的讲故事干预措施，为居住在美国的朝鲜族人预防 HPV 和 HPV 相关癌症

• 批准号: 10428417
• 负责人: MinJin Kim
• 金额: $ 16.39万
• 依托单位: UNIVERSITY OF CINCINNATI
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-09-23 至 2025-07-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10428417
• 关键词: Area; Artificial Intelligence; Asian; Asian population; Attitude; Award; Behavior; Black Populations; Cancer Etiology; Clinical Management; Clinical Trials; Collaborations; Communication; Communities; Data; Data Aggregation; Disease; Documentation; Ethnic Origin; Feasibility Studies; Future; Genital Human Papilloma Virus Infection; Goals; HPV-High Risk; Happiness; Health; Health Disparities Research; Health Promotion; Health behavior outcomes; Hispanic Populations; Human; Human Papilloma Virus Vaccination; Human Papilloma Virus Vaccine; Human Papilloma Virus-Related Malignant Neoplasm; Human Papillomavirus; Human papilloma virus infection; Incidence; Individual; Infection; International; Intervention; Intervention Studies; K-Series Research Career Programs; Knowledge; Korean American; Koreans; Leadership; Malignant Neoplasms; Malignant Vaginal Neoplasm; Malignant neoplasm of anus; Malignant neoplasm of cervix uteri; Malignant neoplasm of penis; Malignant neoplasm of vulva; Manuals; Measures; Mediating; Mediation; Medical; Mentored Patient-Oriented Research Career Development Award; Mentors; Mentorship; Methods; Mexican Americans; Minority; Minority Groups; Mission; Motivation; Not Hispanic or Latino; Online Systems; Outcome; Participant; Persons; Population; Preparation; Prevalence; Prevention program; Preventive; Procedures; Randomized; Randomized Controlled Trials; Reduce health disparities; Research; Research Design; Research Methodology; Research Training; Resources; Risk; Scientist; Sexually Transmitted Diseases; Statistical Methods; Structure; Subgroup; System; Technology; Testing; Throat Cancer; Time; Training; Transcultural Nursing; United States National Institutes of Health; Vaccination; Vaccines; Voice; Woman; acceptability and feasibility; aged; base; cancer prevention; cancer statistics; career; chatbot; college; design; digital; disorder prevention; effectiveness outcome; effectiveness testing; efficacy evaluation; experience; health communication; health data; health difference; health disparity; health equity; health equity promotion; implementation outcomes; improved; innovation; insight; longitudinal analysis; mHealth; malignant mouth neoplasm; men; multiphase optimization strategy; novel; operation; post intervention; post-doctoral training; pragmatic trial; pre-doctoral; prevent; primary outcome; programs; recruit; retention rate; satisfaction; secondary outcome; skills; theories; therapy design; usability; vaccine acceptance; young adult; young man; young woman

PROJECT SUMMARY/ABSTRACT The primary goal of this K23 award is to provide Dr. Minjin Kim with the structured advanced research training, protected time, and mentoring necessary for improving health disparities, health promotion, disease prevention, and innovation using technology to improve health and to reach underserved, under-resourced populations. Candidate: Dr. Kim is a transcultural nurse scientist dedicated to health disparities research using a narrative or “storytelling” approach to capture the voices of a diverse range of people and communities. Her long-term goal is to design and implement sustainable disease prevention programs leveraging technologies that are theory- based, culturally inclusive, and personally relevant to reduce health disparities and promote health equity, improve preventive health behaviors and outcomes, and reach underserved, high-need populations. Dr. Kim’s short-term goal is to employ storytelling interventions leveraging artificial intelligence (AI) chatbots that facilitate timely, effective, and sustained motivation for vaccination to prevent HPV-related infections and cancers. Research: Human papillomavirus (HPV) infection is a sexually transmitted infection with 3 out of 4 new infections occurring in individuals aged 15 to 24. Although HPV vaccine is safe and effective at preventing HPV-related infections and cancers, our preliminary study has shown that only 1 in 5 English-speaking, college-educated Korean American women aged 18 to 26 in the Northeast U.S. had received the HPV vaccine (19%). Dr. Kim’s storytelling video-based intervention leveraging AI chatbot technology (K-Talk) delivers a user-centered experience to promote HPV vaccination behavior among Korean Americans aged 18 to 26. The study aims to 1) adapt and refine the previously developed K-Talk and 2) conduct a pilot Multiphase Optimization Strategy-based trial to assess feasibility, acceptability, and preliminary efficacy of K-Talk. The proposed study assesses the primary outcome (HPV vaccine uptake) by obtaining photo documentation of an HPV vaccination card. This study has a substantial opportunity to reach underserved, hard-to-reach Korean Americans and other minorities. K-Talk is a promising intervention to promote HPV vaccination as a means of cancer prevention. Mentoring/Training: With the expertise of the transdisciplinary mentoring team and consultants from inside and outside of Cincinnati, Dr. Kim will achieve her appointed research and career goals in five domains to advance her program of research through this award. These domains are: designing intervention studies using state-of- the-art research design, mHealth and chatbot-based technologies to improve health communication and dissemination of the interventions, conducting and managing clinical trials and pragmatic trials, advanced statistical methods for clinical trials data as well as communication and leadership skills. The proposed research and training will enable Dr. Kim to independently conduct a future pragmatic trial (R01) that evaluates efficacy of the K-Talk intervention piloted in this proposal.

项目概要/摘要 该 K23 奖项的主要目标是为 Minjin Kim 博士提供结构化的高级研究培训， 受保护的时间，以及改善健康差距、健康促进、疾病预防所必需的指导， 利用技术改善健康并惠及服务不足、资源不足的人群的创新。 候选人：Kim 博士是一位跨文化护士科学家，致力于使用叙述或 “讲故事”的方法来捕捉不同人群和社区的声音。她的长期目标 是利用理论技术设计和实施可持续的疾病预防计划 具有基础性、文化包容性和个人相关性，以减少健康差异并促进健康公平， 改善预防性健康行为和结果，并覆盖服务不足、高需求人群。金博士的 短期目标是利用人工智能（AI）聊天机器人进行讲故事干预，以促进 及时、有效和持续的疫苗接种动机，以预防 HPV 相关感染和癌症。 研究：人乳头瘤病毒 (HPV) 感染是一种性传播感染，新感染病例中有四分之三 发生在 15 至 24 岁的个体中。尽管 HPV 疫苗在预防 HPV 相关疾病方面是安全有效的 感染和癌症，我们的初步研究表明，只有五分之一的讲英语、受过大学教育的人 美国东北部 18 至 26 岁的韩裔美国女性接种了 HPV 疫苗（19%）。金博士的 利用人工智能聊天机器人技术（K-Talk）讲故事的基于视频的干预提供了以用户为中心的 促进 18 至 26 岁韩裔美国人接种 HPV 疫苗行为的经验。该研究旨在 1) 调整和完善之前开发的 K-Talk，2) 进行基于多阶段优化策略的试点 旨在评估 K-Talk 的可行性、可接受性和初步功效的试验。拟议的研究评估了 通过获取 HPV 疫苗接种卡的照片记录来获得主要结果（HPV 疫苗接种）。这 这项研究为接触服务不足、难以接触到的韩裔美国人和其他少数族裔提供了大量机会。 K-Talk 是一项很有前途的干预措施，可促进 HPV 疫苗接种作为癌症预防的一种手段。 指导/培训：凭借跨学科指导团队和内部和外部顾问的专业知识 在辛辛那提之外，金博士将在五个领域实现她指定的研究和职业目标，以推进 她通过该奖项的研究计划。这些领域是： 使用现状设计干预研究 最先进的研究设计、移动医疗和基于聊天机器人的技术，以改善健康沟通和 传播干预措施、开展和管理临床试验和实用试验、高级 临床试验数据的统计方法以及沟通和领导技能。拟议的研究 培训将使 Kim 博士能够独立进行未来的实用试验 (R01)，以评估以下药物的功效： 本提案中试行的 K-Talk 干预措施。