Dual Beckman Coulter DxH 690T and Beckman Coulter DxH 560 AL

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Abstract Texas Biomedical Research Institute (Texas Biomed) is a non-profit, independent research institute, focused on infectious disease research. It is also the host institution for the Southwest National Research Primate Center (SNPRC), one of the seven NIH-funded NPRCs in the nation. SNPRC houses ~ 3000 nonhuman primates (NHPs). The SNPRC Pathology Core supports diagnostic, anatomic, morphologic, molecular and clinical pathology needs of > 100 internal and external scientists. Many internal faculty members also extensively utilize rodents for research that is supported by the Pathology Core staff. We request S10 support to purchase a dual Beckman Coulter DxH 690T and Beckman Coulter DxH 560 AL for hematology analyses of experimental and colony health data of NHPs and rodents. The requested replacement unit will replace and upgrade the clinical diagnostic services that are currently provided by end-of-life equipment at Texas Biomed. The DxH 690T is a suitable, cost-effective replacement for, and is capable of reproducing all analysis parameters of an existing DxH 800. The DxH 560L performs hematology analysis using miniscule volumes of blood, which makes hematology analysis possible for studies involving rodents and small NHPs.