Dual Beckman Coulter DxH 690T and Beckman Coulter DxH 560 AL

摘要 德克萨斯生物医学研究所（Texas Biomed）是一家非营利性的独立研究机构，专注于 传染病研究。它也是西南国家灵长类动物研究中心的主办机构 （SNPRC），美国国家卫生研究院资助的七个NPRC之一。SNPRC饲养了约3000只非人灵长类动物 （NHPs）。SNPRC病理核心支持诊断、解剖、形态、分子和临床 病理学需要> 100名内部和外部科学家。许多内部教员也广泛地 利用啮齿动物进行病理学核心人员支持的研究。我们请求S10支持以购买 双通道Beckman Coulter DxH 690 T和Beckman Coulter DxH 560 AL，用于血液学分析 NHP和啮齿动物的实验和群体健康数据。所要求的更换单位将取代和 升级目前由Texas Biomed的报废设备提供的临床诊断服务。 DxH 690 T是一种合适的、具有成本效益的替代品，能够重现所有分析参数 现有的DxH 800 DxH 560 L使用微量血液进行血液学分析， 使得涉及啮齿动物和小型NHP的研究的血液学分析成为可能。

Abstract Texas Biomedical Research Institute (Texas Biomed) is a non-profit, independent research institute, focused on infectious disease research. It is also the host institution for the Southwest National Research Primate Center (SNPRC), one of the seven NIH-funded NPRCs in the nation. SNPRC houses ~ 3000 nonhuman primates (NHPs). The SNPRC Pathology Core supports diagnostic, anatomic, morphologic, molecular and clinical pathology needs of > 100 internal and external scientists. Many internal faculty members also extensively utilize rodents for research that is supported by the Pathology Core staff. We request S10 support to purchase a dual Beckman Coulter DxH 690T and Beckman Coulter DxH 560 AL for hematology analyses of experimental and colony health data of NHPs and rodents. The requested replacement unit will replace and upgrade the clinical diagnostic services that are currently provided by end-of-life equipment at Texas Biomed. The DxH 690T is a suitable, cost-effective replacement for, and is capable of reproducing all analysis parameters of an existing DxH 800. The DxH 560L performs hematology analysis using miniscule volumes of blood, which makes hematology analysis possible for studies involving rodents and small NHPs.