UCSF-UCB TRAC Clinical Sciences Core

UCSF-UCB TRAC 临床科学核心

• 批准号: 10431542
• 负责人: Priya B. Shete
• 金额: $ 20.75万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN FRANCISCO
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-08-02 至 2027-05-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10431542
• 关键词: Affect; Area; Basic Science; Bioinformatics; Biological; Biomedical Research; Biometry; COVID-19 pandemic; Caring; Clinical; Clinical Research; Clinical Sciences; Collaborations; Communities; Conceptions; Consultations; Data; Data Science; Data Set; Databases; Development; Discipline; Disease; Dissemination and Implementation; Doctor of Philosophy; Ecosystem; Epidemiology; Evaluation; Faculty; Feedback; Fostering; Generations; Goals; Health Status; Human; Human Subject Research; Incidence; Individual; Infrastructure; Infusion procedures; International; Intervention Trial; Investigation; Link; Mentors; Mentorship; Methodology; Methods; Outcome; Participant; Population Sciences; Populations at Risk; Prevention; Prospective cohort; Public Health; Research; Research Design; Research Methodology; Research Personnel; Resources; Risk; Scientist; Services; Social Sciences; Source; Specimen; Statistical Data Interpretation; Training; Tuberculosis; base; bench to bedside; career development; clinical center; clinical research site; cohort; community center; community engagement; cost; data management; design; experience; improved; innovation; interdisciplinary approach; meetings; mortality; multidisciplinary; novel; pandemic disease; population health; programs; repository; research study; scale up; searchable database; tool; translational study

PROJECT SUMMARY – Clinical Science Core Progress towards meeting global public health tuberculosis (TB) targets for reductions in incidence, mortality and catastrophic costs have been slow, and appear to have stagnated due the recent COVID-19 pandemic. Without reinvigorating TB clinical research with an infusion of new investigators, novel perspectives, and cutting-edge innovation, we remain at risk of allowing the TB pandemic to continue unabated. The goal of the Clinical Science Core of the UCSF-UCB TRAC is to augment existing UCSF and UCB resources to accelerate clinical research by engaging New Investigators and established investigators new-to-TB, and by reducing the barrier to conducting high-quality, innovating clinical research. UCSF-UCB TRAC Clinical Science Core will support investigators by 1) providing consultation on key aspects of TB clinical research; 2) providing consultation about novel methodologic approaches in clinical research that may be applied to TB; 3) facilitating access to clinical cohorts, datasets, bio-specimens, and clinical research tools; 4) supporting meaningful community engagement via a TRAC TB Community Advisory Board; 5) supporting career development of new investigators with targeted mentorship. The Clinical Science Core will encourage an interdisciplinary approach to TB clinical research by making services and resources available for researchers from diverse fields including basic sciences, epidemiology, bioinformatics, public health, social sciences and clinical sciences. The Clinical Science Core hopes to attract and inspire a new generation of TB scientists to accelerate TB biomedical and clinical research with the support of UCSF-UCB TRAC faculty who are leaders in TB clinical sciences.

项目总结-临床科学核心 在实现全球公共卫生结核病发病率、死亡率和 和灾难性的成本一直很慢，似乎由于最近的COVID-19而停滞不前 流行病如果不通过注入新的研究人员、新的视角来重振结核病临床研究， 和尖端创新，我们仍然面临着让结核病大流行继续有增无减的风险。的目标 UCSF-UCB TRAC的临床科学核心是增加现有的UCSF和UCB资源， 通过聘请新的研究者和新的结核病研究者来加速临床研究， 减少进行高质量创新临床研究的障碍。UCSF-UCB TRAC临床科学 核心将通过以下方式支持研究者：1）就结核病临床研究的关键方面提供咨询; 2） 就可能应用于结核病的临床研究中的新方法学方法进行咨询; 3）促进 获得临床队列、数据集、生物标本和临床研究工具; 4）支持有意义的 通过TRAC结核病社区咨询委员会进行社区参与; 5）支持新的职业发展 有针对性的指导调查员。临床科学核心将鼓励跨学科的方法 通过为来自不同领域的研究人员提供服务和资源， 基础科学、流行病学、生物信息学、公共卫生、社会科学和临床科学。临床 科学核心希望吸引和激励新一代结核病科学家，以加速结核病生物医学和 在UCSF-UCB TRAC教师的支持下进行临床研究，他们是结核病临床科学的领导者。