UCSF-UCB TRAC Clinical Sciences Core

项目摘要-临床科学核心 在实现降低发病率和死亡率的全球公共卫生结核病目标方面取得的进展 而且灾难性的成本一直很慢，由于最近的新冠肺炎，似乎已经停滞不前 大流行。如果没有注入新的研究人员，新的视角， 和尖端创新，我们仍然面临允许结核病大流行有增无减的风险。的目标是 UCSF-UCB TRAC的临床科学核心是将现有的UCSF和UCB资源增加到 通过聘用新的研究人员和已有的结核病新手研究人员，以及通过 降低进行高质量、创新性临床研究的障碍。加州大学旧金山分校-UCB TRAC临床科学 CORE将通过以下方式支持研究人员：1)就结核病临床研究的关键方面提供咨询；2)提供 就可能应用于结核病的临床研究的新方法提供咨询；3)促进 获得临床队列、数据集、生物标本和临床研究工具；4)支持有意义的 通过TRAC结核病社区咨询委员会进行社区参与；5)支持新的职业发展 有针对性指导的调查人员。临床科学核心将鼓励跨学科的方法 通过为来自不同领域的研究人员提供服务和资源来进行结核病临床研究，包括 基础科学、流行病学、生物信息学、公共卫生、社会科学和临床科学。《临床》 Science Core希望吸引和激励新一代结核病科学家加快结核病生物医学和 在加州大学旧金山分校-UCB TRAC教员的支持下进行的临床研究，他们是结核病临床科学的领导者。

PROJECT SUMMARY – Clinical Science Core Progress towards meeting global public health tuberculosis (TB) targets for reductions in incidence, mortality and catastrophic costs have been slow, and appear to have stagnated due the recent COVID-19 pandemic. Without reinvigorating TB clinical research with an infusion of new investigators, novel perspectives, and cutting-edge innovation, we remain at risk of allowing the TB pandemic to continue unabated. The goal of the Clinical Science Core of the UCSF-UCB TRAC is to augment existing UCSF and UCB resources to accelerate clinical research by engaging New Investigators and established investigators new-to-TB, and by reducing the barrier to conducting high-quality, innovating clinical research. UCSF-UCB TRAC Clinical Science Core will support investigators by 1) providing consultation on key aspects of TB clinical research; 2) providing consultation about novel methodologic approaches in clinical research that may be applied to TB; 3) facilitating access to clinical cohorts, datasets, bio-specimens, and clinical research tools; 4) supporting meaningful community engagement via a TRAC TB Community Advisory Board; 5) supporting career development of new investigators with targeted mentorship. The Clinical Science Core will encourage an interdisciplinary approach to TB clinical research by making services and resources available for researchers from diverse fields including basic sciences, epidemiology, bioinformatics, public health, social sciences and clinical sciences. The Clinical Science Core hopes to attract and inspire a new generation of TB scientists to accelerate TB biomedical and clinical research with the support of UCSF-UCB TRAC faculty who are leaders in TB clinical sciences.