UCSF-UCB TRAC Clinical Sciences Core

项目摘要 – 临床科学核心 在实现降低发病率和死亡率的全球公共卫生结核病目标方面取得进展 由于最近的 COVID-19，灾难性成本的进展缓慢，并且似乎已停滞 大流行。如果不注入新的研究人员、新的观点来重振结核病临床研究， 和尖端创新，我们仍然面临着结核病大流行继续有增无减的风险。目标是 UCSF-UCB TRAC 的临床科学核心是增强现有的 UCSF 和 UCB 资源， 通过吸引新的研究者和新的结核病研究者来加速临床研究，并通过 减少进行高质量、创新临床研究的障碍。 UCSF-UCB TRAC 临床科学 Core 将通过以下方式支持研究人员：1）提供结核病临床研究关键方面的咨询； 2）提供 有关可应用于结核病的临床研究新方法的咨询； 3）促进 访问临床队列、数据集、生物样本和临床研究工具； 4）支持有意义 通过 TRAC TB 社区咨询委员会进行社区参与； 5）支持新人的职业发展 调查人员进行有针对性的指导。临床科学核心将鼓励跨学科方法 通过为不同领域的研究人员提供服务和资源，包括结核病临床研究 基础科学、流行病学、生物信息学、公共卫生、社会科学和临床科学。临床 Science Core 希望吸引和激励新一代结核病科学家加速结核病生物医学和 临床研究得到了 UCSF-UCB TRAC 教师的支持，他们是结核病临床科学的领导者。

PROJECT SUMMARY – Clinical Science Core Progress towards meeting global public health tuberculosis (TB) targets for reductions in incidence, mortality and catastrophic costs have been slow, and appear to have stagnated due the recent COVID-19 pandemic. Without reinvigorating TB clinical research with an infusion of new investigators, novel perspectives, and cutting-edge innovation, we remain at risk of allowing the TB pandemic to continue unabated. The goal of the Clinical Science Core of the UCSF-UCB TRAC is to augment existing UCSF and UCB resources to accelerate clinical research by engaging New Investigators and established investigators new-to-TB, and by reducing the barrier to conducting high-quality, innovating clinical research. UCSF-UCB TRAC Clinical Science Core will support investigators by 1) providing consultation on key aspects of TB clinical research; 2) providing consultation about novel methodologic approaches in clinical research that may be applied to TB; 3) facilitating access to clinical cohorts, datasets, bio-specimens, and clinical research tools; 4) supporting meaningful community engagement via a TRAC TB Community Advisory Board; 5) supporting career development of new investigators with targeted mentorship. The Clinical Science Core will encourage an interdisciplinary approach to TB clinical research by making services and resources available for researchers from diverse fields including basic sciences, epidemiology, bioinformatics, public health, social sciences and clinical sciences. The Clinical Science Core hopes to attract and inspire a new generation of TB scientists to accelerate TB biomedical and clinical research with the support of UCSF-UCB TRAC faculty who are leaders in TB clinical sciences.