Tampa Bay Life Sciences Computing Commons (TBLSCC)

坦帕湾生命科学计算共享中心 (TBLSCC)

• 批准号: 10430990
• 负责人: Steven Allen Eschrich
• 金额: $ 199.98万
• 依托单位: H. LEE MOFFITT CANCER CTR & RES INST
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-05-15 至 2024-05-14
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10430990
• 关键词: American; Area; Artificial Intelligence; Biological Sciences; Cancer Center; Collaborations; Communicable Diseases; Communities; Complement; Comprehensive Cancer Center; Computer software; Diabetes Mellitus; Environment; Equipment; Florida; Funding; Genomics; Growth; Health; Health Insurance Portability and Accountability Act; High Performance Computing; Infrastructure; Institutes; Legal patent; Machine Learning; Malignant Neoplasms; Mathematics; Medical Imaging; Minor; Modeling; NCI Center for Cancer Research; Oncology; Policies; Procedures; Public Health Informatics; Research; Research Personnel; Resources; Science; Services; System; United States National Institutes of Health; Universities; base; catalyst; cluster computing; computational platform; computing resources; end of life; innovation; open data; radiomics

Project Summary/Abstract Funds are requested for the Tampa Bay Life Sciences Computing Commons (TBLSCC), to refresh outdated equipment and expand existing hardware (84% net increase in cores). The TBLSCC will serve as a catalyst to consolidate life-sciences based compute capacity, resulting in fourfold expansion of the existing facility. The TBLSCC will meet current demands, support recent NIH-funded growth in quantitative sciences, leverage the shared expertise of computational researchers at Moffitt Cancer Center (MCC) and the University of South Florida (USF), and enable cross-institutional collaboration not previously possible. This proposal includes 23 life sciences research groups in the Tampa Bay area, with more than 15 NIH funded research Major or Minor Users representing over $100 million in annual NIH funding. The scientific use cases for this computational platform include cancer, diabetes, infectious disease, genomics, radiomics, artificial intelligence, and modelling research. Overall, 85 life sciences research groups would directly benefit from the new system. MCC operates an 82-node, 1120-core high-performance computing (HPC) cluster. The current hardware and software environment is end-of-life, slowing MCC research. Likewise, the USF Health Informatics Institute (HII) uses an 80 node, 1388 core cluster at end of life. USF recently developed a 77 node/1668 core/16TB restricted research (HIPAA-compliant) life sciences cluster (RRA) to complement their 435 node/9088 core/55 TB general-purpose cluster. RRA includes HIPAA-compliant storage, as well as policies and procedures for managing access for genomics and medical imaging research. We seek funds to purchase 86 nodes (6016 cores). We will leverage the existing RRA infrastructure to create the TBLSCC, a 163 node/7684 core cluster available for MCC/USF users that can accommodate 20% annual growth in computing intensive research. This resource will support cross-institutional collaboration, enable open science, and manage increased demands on computational resources leveraging shared MCC/USF research needs, USF research computing expertise, and MCC shared services computational expertise. MCC and USF are co-located with almost $300 million per year of NIH funding. MCC is the only Florida-based NCI-designated Comprehensive Cancer Center with innovative research, including Integrated Mathematical Oncology and Machine Learning. USF performs high-impact global research as a Preeminent Research University in Florida and is eighth among American public research universities in generating new patents. The TBLSCC will support this vibrant life science research community and provide a platform for health-focused innovations.

项目概要/摘要 需要为坦帕湾生命科学计算共享区 (TBLSCC) 提供资金，以刷新过时的 设备并扩展现有硬件（核心净增加 84%）。 TBLSCC 将作为催化剂 整合基于生命科学的计算能力，使现有设施扩大四倍。这 TBLSCC 将满足当前需求，支持近期 NIH 资助的定量科学发展，利用 莫菲特癌症中心 (MCC) 和南方大学计算研究人员共享专业知识 佛罗里达州（USF），并实现以前不可能的跨机构合作。该提案包括 23 坦帕湾地区的生命科学研究小组，拥有超过 15 项 NIH 资助的主要或次要研究 用户代表 NIH 年度资助超过 1 亿美元。这种计算的科学用例 平台包括癌症、糖尿病、传染病、基因组学、放射组学、人工智能和建模 研究。总体而言，85 个生命科学研究小组将直接受益于新系统。 MCC 运营着一个 82 节点、1120 核高性能计算 (HPC) 集群。目前的硬件和 软件环境已结束生命周期，减缓了 MCC 的研究。同样，USF 健康信息研究所 (HII) 在生命周期结束时使用 80 个节点、1388 个核心的集群。 USF最近开发了77节点/1668核心/16TB受限 研究（符合 HIPAA 标准）生命科学集群 (RRA)，以补充其 435 个节点/9088 个核心/55 TB 通用集群。 RRA 包括符合 HIPAA 的存储以及以下政策和程序： 管理基因组学和医学成像研究的访问。我们寻求资金购买86个节点（6016 核心）。我们将利用现有的 RRA 基础设施来创建 TBLSCC，一个 163 个节点/7684 个核心集群 可供 MCC/USF 用户使用，可适应计算密集型研究每年 20% 的增长。这 资源将支持跨机构合作、实现开放科学并管理不断增长的需求 利用共享的 MCC/USF 研究需求、USF 研究计算专业知识的计算资源， 和 MCC 共享服务计算专业知识。 MCC 和 USF 位于同一地点，每年获得 NIH 近 3 亿美元的资助。 MCC 是唯一一家总部位于佛罗里达州的 NCI 指定的综合癌症中心，拥有创新研究，包括综合数学 肿瘤学和机器学习。南佛罗里达大学作为杰出研究开展高影响力的全球研究 佛罗里达大学在创造新专利方面在美国公立研究型大学中排名第八。这 TBLSCC 将支持这个充满活力的生命科学研究社区，并为关注健康的人们提供一个平台 创新。