Basic Science Core - Biosafety & Biocontainment Core (BBC)

德克萨斯州Biomed IN-TRAC生物安全和生物防护核心（BBC）-摘要 这个核心的目标是建立一个个性化的生物安全和生物遏制培训课程， 培养一代结核病研究人员，使他们做好准备，在生物防护措施中工作并取得优异成绩 环境进行研究，以推进该领域。对于从事结核病研究的新研究人员以及 对于想要进入结核病研究领域的知名研究人员来说，了解以下内容至关重要： 生物安全和生物防护环境，包括工作的优势和局限性的知识 为了让他们实现职业目标正确进行风险评估的能力 包括彻底了解生物防护的设备和程序，将进一步确保 结核病研究的创新，特别是在资源有限的地区。我们的目标是：目标1。建立和管理 个性化的生物安全和生物防护课程。在这一目标中，分阶段办法（评估和 教学阶段），以提供全面和个性化的培训。目标二。执行 针对IN-TRAC参与者的生物安全和生物防护培训方案。在这一目标下， 将执行为IN-TRAC参与者制定的生物防护培训计划。参与者将 学习如何在高密闭BSL 3设施中安全有效地运行。我们把它分成三份 部分：生物防护设施操作，一般程序和应急反应演习。目标3. 将风险评估和缓解战略应用于新兴技术和多种灾害情景。 新技术往往带来不可预见的生物安全风险。配备一般生物防护和结核分枝杆菌 具体程序的知识，参与者将能够正确地评估和实施程序， 遇到新兴技术，并制定程序，以安全地实现其研究目标。 在完成这一核心课程后，新的结核病研究人员将准备/熟练地在一个 生物防护环境，包括在结核病领域取得成功所需的一般和专门技术。 重要的是，核心预算资源调拨目标参与者将编写一份关于优缺点的书面和口头摘要， IN-TRAC项目的经验。

Texas Biomed IN-TRAC Biosafety & Biocontainment Core (BBC) – ABSTRACT The goal of this core is to establish a personalized Biosafety & Biocontainment training curriculum for the next generation of tuberculosis (TB) researchers in order to prepare them to work and excel within the biocontainment environment performing studies to advance the field. For a new investigator pursuing TB research as well as for well-established investigators who want to enter the TB research field, it is critical for them to understand biosafety and the biocontainment environment, including knowledge of the strengths and limitations of working in biocontainment, in order for them to achieve their career goals. The ability to properly conduct risk assessment including a thorough understanding of equipment and procedures in biocontainment, will further ensure innovations in TB research, especially in resource limited areas. Our Aims are to: Aim 1. Establish and manage a personalized Biosafety & Biocontainment curriculum. In this Aim a phased approach (assessment and didactic phases) will be implemented to provide comprehensive and customized training. Aim 2. Execute a Biosafety & Biocontainment training program for IN-TRAC participants. In this aim, a personalized Biocontainment training program established for each IN-TRAC participant will be executed. Participants will learn how to function safely and effectively in a high-containment BSL3 facility. We will divide this into three segments: Biocontainment facility operations, General Procedures and Emergency Response Drills. Aim 3. Apply risk assessment and mitigation strategies to emerging technology and multi-hazard scenarios. New technology often introduces unforeseeable biosafety risks. Equipped with general biocontainment and M.tb procedure-specific knowledge, participants will be able to properly evaluate and implement procedures when encountering emerging technology and develop procedures to safety achieve their research goals. Upon completion of this core curriculum, new TB researchers will be prepared/proficient in working in a biocontainment environment, including general and specialized techniques required for success in the TB field. Importantly, IN-TRAC participants will prepare a written and oral summary about the strengths and weaknesses of experience for the IN-TRAC program.