Methods Core
方法核心
基本信息
- 批准号:10436045
- 负责人:
- 金额:$ 128.66万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2022
- 资助国家:美国
- 起止时间:2022-08-01 至 2027-07-31
- 项目状态:未结题
- 来源:
- 关键词:AddressApplications GrantsAreaArtificial IntelligenceBehaviorBehavior TherapyBig Data MethodsCapitalChildhoodCollaborationsCommunitiesCommunity HealthDataData AnalysesData CollectionData ElementDevelopmentElementsEnsureEnvironmentEvaluationEvidence based interventionFosteringFutureGenerationsGoalsGrantGrowth and Development functionHealthHealth systemHealthcare SystemsInformation TechnologyInfrastructureInstitutesInterventionLeadershipMental HealthMentorsMethodologyMethodsModelingMonitorNational Institute of Mental HealthNerveOhioParentsPatient RepresentativePatientsPediatric HospitalsPilot ProjectsPopulationPopulation InterventionPopulation StudyPositioning AttributePractical Robust Implementation and Sustainability ModelPredictive AnalyticsPreparationPrevention ResearchProcessProductivityProtocols documentationPublic HealthQualitative MethodsQuality ControlResearchResearch DesignResearch InstituteResearch MethodologyResearch PersonnelResearch Project GrantsResourcesRiskScienceServicesStandardizationStatistical ModelsSuicideSuicide preventionTestingUniversitiesWorkYouthacute carecareerclinical decision-makingdata harmonizationdata managementdata sharingdata standardsdesigndigital healthhealth managementimplementation frameworkimplementation scienceimplementation strategyimprovedinnovationinterdisciplinary collaborationmedical specialtiesmodel designmultidisciplinarynoveloutreachpopulation healthpreventive interventionprogram disseminationprogramspublic health interventionreducing suicidesocial health determinantssocial structurestudent trainingsuccesssuicide rateworking group
项目摘要
ABSTRACT – METHODS CORE
The ASPIRES Methods Core (MC) brings together investigators from diverse and complementary backgrounds
to collectively address design, implementation, methodological, and technological challenges that impede
progress toward effectively reducing the youth suicide rate. Our transdisciplinary team includes experts in
study design methodology for behavioral and population interventions, predictive analytics to improve clinical
decision making, development of digital health interventions, implementation science, qualitative methods,
integration of multi-level data elements representative of patient and community health, and geospatial
modeling of environment and social structure on population health. The MC capitalizes on substantial
institutional infrastructure and intellectual capital at both The Abigail Wexner Research Institute (AWRI) at
Nationwide Children’s Hospital (NCH) and The Ohio State University (OSU), and Co-Leaders Drs. Brock,
McAlearney, and Lin have each led both specialized and multidisciplinary teams with broad impact spanning
multiple areas of health. The MC will work with ASPIRES investigators to facilitate in a pediatric population 1)
development and testing of novel and scalable interventions and research-generated resources with significant
appeal for stakeholders; 2) rapid and widespread dissemination of new, effective practices; 3) continuous
improvement of suicide prevention interventions delivered in real-world settings; 4) interdisciplinary team
science to facilitate novel and convergent solutions to intractable suicide prevention challenges; and 5) training
of students, fellows, early career, and advanced investigators from diverse backgrounds to increase the
diversity of investigators conducting cutting-edge translational suicide prevention research. Our MC provides a
methodological anchor connecting all ASPIRES projects, and our transdisciplinary team with substantial
expertise, resources, and infrastructure at both NCH and OSU will ensure that all ASPIRES projects are
conducted with scientific rigor and broadly disseminated. Creative partnerships with the Zero Suicide Institute
and the OSU CCTS Pilot Project Program augment outreach, engagement, and dissemination. Methodological
and technological advances from our MC provide innovative approaches to overcoming challenges facing
behavioral interventions for reducing the youth suicide rate. Synergistic study design elements across
ASPIRES projects provide unique opportunities to study implementation and efficacy aspects of suicide
prevention interventions across primary, specialty, and acute care. Collectively, these developments support
innovative and rigorous evaluation of ASPIRES interventions and provide the groundwork for further design
and refinement of implementation strategies necessary to scale these interventions in future studies.
摘要-方法核心
ASPIRES方法核心(MC)汇集了来自不同和互补背景的研究人员
共同应对阻碍我们实现目标的设计、实施、方法和技术挑战,
在有效降低青少年自杀率方面取得进展。我们的跨学科团队包括以下方面的专家:
行为和人群干预的研究设计方法,预测分析,以改善临床
决策,数字健康干预措施的发展,实施科学,定性方法,
代表患者和社区健康的多层次数据元素的集成,以及地理空间
环境和社会结构对人群健康的影响模型。MC充分利用了
Abigail Wexner研究所(AWRI)的机构基础设施和知识资本,
全国儿童医院(NCH)和俄亥俄州州立大学(OSU),以及共同领导人布罗克博士,
McAllearney和Lin各自领导了专业和多学科团队,具有广泛的影响力,
多个健康领域。MC将与ASPIRES研究者合作,以促进儿科人群1)
开发和测试新的和可扩展的干预措施和研究产生的资源,
呼吁利益攸关方; 2)迅速和广泛传播新的有效做法; 3)持续
改善在现实世界环境中提供的自杀预防干预措施; 4)跨学科团队
科学,以促进新的和收敛的解决方案,以解决棘手的自杀预防挑战;和5)培训
来自不同背景的学生,研究员,早期职业生涯和高级研究人员,以增加
多样性的研究人员进行尖端的转化自杀预防研究。我们的MC提供
方法论的锚连接所有ASPIRES项目,我们的跨学科团队与实质性的
NCH和OSU的专业知识、资源和基础设施将确保所有ASPIRES项目
以科学的严谨性进行并广泛传播。与零自杀研究所(Zero Suicide Institute)合作
和俄勒冈州立大学CCTS试点项目计划扩大了外展,参与和传播。方法学
我们的MC的技术进步为克服面临的挑战提供了创新方法
降低青少年自杀率的行为干预。协同研究设计要素
ASPIRES项目为研究自杀的实施和有效性方面提供了独特的机会
在初级、专科和急症护理中采取预防干预措施。总的来说,这些发展支持
对ASPIRES干预措施进行创新和严格的评估,并为进一步设计提供基础
并完善必要的实施战略,以在未来的研究中扩大这些干预措施。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Guy Brock其他文献
Guy Brock的其他文献
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{{ truncateString('Guy Brock', 18)}}的其他基金
A cohesive statistical approach for missing values in high-dimensional metabolomics data
针对高维代谢组学数据中缺失值的内聚统计方法
- 批准号:
9433329 - 财政年份:2017
- 资助金额:
$ 128.66万 - 项目类别:
BD4ISU: Big Data for Indiana State University
BD4ISU:印第安纳州立大学的大数据
- 批准号:
9883642 - 财政年份:2017
- 资助金额:
$ 128.66万 - 项目类别:
Integrated Analysis: Epigenetic Regulation of Gene Expression During Orofacial De
综合分析:口面部脱发过程中基因表达的表观遗传调控
- 批准号:
8385921 - 财政年份:2012
- 资助金额:
$ 128.66万 - 项目类别:
Integrated Analysis: Epigenetic Regulation of Gene Expression During Orofacial De
综合分析:口面部脱发过程中基因表达的表观遗传调控
- 批准号:
8537402 - 财政年份:2012
- 资助金额:
$ 128.66万 - 项目类别: