Methods Core
方法核心
基本信息
- 批准号:10436045
- 负责人:
- 金额:$ 128.66万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2022
- 资助国家:美国
- 起止时间:2022-08-01 至 2027-07-31
- 项目状态:未结题
- 来源:
- 关键词:AddressApplications GrantsAreaArtificial IntelligenceBehaviorBehavior TherapyBig Data MethodsCapitalChildhoodCollaborationsCommunitiesCommunity HealthDataData AnalysesData CollectionData ElementDevelopmentElementsEnsureEnvironmentEvaluationEvidence based interventionFosteringFutureGenerationsGoalsGrantGrowth and Development functionHealthHealth systemHealthcare SystemsInformation TechnologyInfrastructureInstitutesInterventionLeadershipMental HealthMentorsMethodologyMethodsModelingMonitorNational Institute of Mental HealthNerveOhioParentsPatient RepresentativePatientsPediatric HospitalsPilot ProjectsPopulationPopulation InterventionPopulation StudyPositioning AttributePractical Robust Implementation and Sustainability ModelPredictive AnalyticsPreparationPrevention ResearchProcessProductivityProtocols documentationPublic HealthQualitative MethodsQuality ControlResearchResearch DesignResearch InstituteResearch MethodologyResearch PersonnelResearch Project GrantsResourcesRiskScienceServicesStandardizationStatistical ModelsSuicideSuicide preventionTestingUniversitiesWorkYouthacute carecareerclinical decision-makingdata harmonizationdata managementdata sharingdata standardsdesigndigital healthhealth managementimplementation frameworkimplementation scienceimplementation strategyimprovedinnovationinterdisciplinary collaborationmedical specialtiesmodel designmultidisciplinarynoveloutreachpopulation healthpreventive interventionprogram disseminationprogramspublic health interventionreducing suicidesocial health determinantssocial structurestudent trainingsuccesssuicide rateworking group
项目摘要
ABSTRACT – METHODS CORE
The ASPIRES Methods Core (MC) brings together investigators from diverse and complementary backgrounds
to collectively address design, implementation, methodological, and technological challenges that impede
progress toward effectively reducing the youth suicide rate. Our transdisciplinary team includes experts in
study design methodology for behavioral and population interventions, predictive analytics to improve clinical
decision making, development of digital health interventions, implementation science, qualitative methods,
integration of multi-level data elements representative of patient and community health, and geospatial
modeling of environment and social structure on population health. The MC capitalizes on substantial
institutional infrastructure and intellectual capital at both The Abigail Wexner Research Institute (AWRI) at
Nationwide Children’s Hospital (NCH) and The Ohio State University (OSU), and Co-Leaders Drs. Brock,
McAlearney, and Lin have each led both specialized and multidisciplinary teams with broad impact spanning
multiple areas of health. The MC will work with ASPIRES investigators to facilitate in a pediatric population 1)
development and testing of novel and scalable interventions and research-generated resources with significant
appeal for stakeholders; 2) rapid and widespread dissemination of new, effective practices; 3) continuous
improvement of suicide prevention interventions delivered in real-world settings; 4) interdisciplinary team
science to facilitate novel and convergent solutions to intractable suicide prevention challenges; and 5) training
of students, fellows, early career, and advanced investigators from diverse backgrounds to increase the
diversity of investigators conducting cutting-edge translational suicide prevention research. Our MC provides a
methodological anchor connecting all ASPIRES projects, and our transdisciplinary team with substantial
expertise, resources, and infrastructure at both NCH and OSU will ensure that all ASPIRES projects are
conducted with scientific rigor and broadly disseminated. Creative partnerships with the Zero Suicide Institute
and the OSU CCTS Pilot Project Program augment outreach, engagement, and dissemination. Methodological
and technological advances from our MC provide innovative approaches to overcoming challenges facing
behavioral interventions for reducing the youth suicide rate. Synergistic study design elements across
ASPIRES projects provide unique opportunities to study implementation and efficacy aspects of suicide
prevention interventions across primary, specialty, and acute care. Collectively, these developments support
innovative and rigorous evaluation of ASPIRES interventions and provide the groundwork for further design
and refinement of implementation strategies necessary to scale these interventions in future studies.
摘要——方法核心
ASPRES 方法核心 (MC) 汇集了来自不同且互补背景的研究人员
共同解决阻碍的设计、实施、方法和技术挑战
有效降低青少年自杀率取得进展。我们的跨学科团队包括以下领域的专家
研究行为和人群干预的设计方法,预测分析以改善临床
决策、数字健康干预措施的开发、实施科学、定性方法、
代表患者和社区健康以及地理空间的多级数据元素的集成
环境和社会结构对人口健康的影响建模。 MC充分利用了
阿比盖尔韦克斯纳研究所 (AWRI) 的机构基础设施和智力资本
全国儿童医院 (NCH) 和俄亥俄州立大学 (OSU) 以及联合领导者 Drs.布洛克,
麦卡利尼和林分别领导了具有广泛影响力的专业和多学科团队
多个健康领域。 MC 将与 ASPIRES 研究人员合作,为儿科人群提供便利 1)
开发和测试新颖且可扩展的干预措施以及研究产生的资源,具有重要意义
利益相关者的呼吁; 2) 快速、广泛传播新的、有效的做法; 3)连续
改善现实世界中的自杀预防干预措施; 4)跨学科团队
科学促进针对棘手的自杀预防挑战的新颖且一致的解决方案; 5)培训
来自不同背景的学生、研究员、早期职业生涯和高级研究人员,以提高
进行前沿转化性自杀预防研究的研究人员的多样性。我们的MC提供
连接所有 ASPIRE 项目的方法论支柱,以及我们的跨学科团队
NCH 和 OSU 的专业知识、资源和基础设施将确保所有 ASPIRES 项目
科学严谨地进行并广泛传播。与零自杀研究所的创造性合作伙伴关系
和 OSU CCTS 试点项目计划增强了外展、参与和传播。方法论
我们的 MC 和技术进步为克服面临的挑战提供了创新方法
降低青少年自杀率的行为干预。协同研究设计元素
ASPIRE 项目提供了独特的机会来研究自杀的实施和功效方面
初级、专科和急症护理的预防干预措施。总的来说,这些发展支持
对 ASPIRES 干预措施进行创新和严格的评估,并为进一步设计奠定基础
并完善必要的实施策略,以在未来的研究中扩展这些干预措施。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Guy Brock其他文献
Guy Brock的其他文献
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{{ truncateString('Guy Brock', 18)}}的其他基金
A cohesive statistical approach for missing values in high-dimensional metabolomics data
针对高维代谢组学数据中缺失值的内聚统计方法
- 批准号:
9433329 - 财政年份:2017
- 资助金额:
$ 128.66万 - 项目类别:
BD4ISU: Big Data for Indiana State University
BD4ISU:印第安纳州立大学的大数据
- 批准号:
9883642 - 财政年份:2017
- 资助金额:
$ 128.66万 - 项目类别:
Integrated Analysis: Epigenetic Regulation of Gene Expression During Orofacial De
综合分析:口面部脱发过程中基因表达的表观遗传调控
- 批准号:
8385921 - 财政年份:2012
- 资助金额:
$ 128.66万 - 项目类别:
Integrated Analysis: Epigenetic Regulation of Gene Expression During Orofacial De
综合分析:口面部脱发过程中基因表达的表观遗传调控
- 批准号:
8537402 - 财政年份:2012
- 资助金额:
$ 128.66万 - 项目类别:














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