Healthy Hearts/ Corazones Saludables: Partnership to promote cardiovascular health in Hispanic and non-Hispanic mothers and children in US home visiting programs

Healthy Hearts/Corazones Saludables:在美国家访计划中合作促进西班牙裔和非西班牙裔母亲和儿童的心血管健康

基本信息

项目摘要

Project Summary/Abstract Cardiovascular disease (CVD) is the leading cause of death in US women, accounting for approximately one of every three female deaths. Obesity is arguably the strongest modifiable target for interventions to prevent CVD and is linked with nearly every other major CVD risk factor, including hypertension, elevated glucose, high cholesterol, poor diet, and physical inactivity. Infants of mothers with obesity are also at increased risk for future obesity and CVD. Our team has developed an empirically validated lifestyle intervention that is remotely delivered and highly successful in reducing body weight and improving CVH in Hispanic and non-Hispanic women and children during pregnancy and postpartum. It is now critical to study ways to disseminate this empirically-validated program. Evidence based home visiting programs (EBHV), which support families from the prenatal period through infancy and early childhood, are an ideal setting to promote CVH, however these programs were not designed with an explicit focus on the prevention of obesity and other CVD risk factors. The proposed research will test the effectiveness of our pre- and postnatal lifestyle intervention as an enhancement to EBHV to promote maternal and child CVH. During an initial 2-year UG3 phase, we will: 1) modify our pre- and postnatal intervention to focus on CVH within EBHV; 2) Work with our EBHV partners to integrate CVH messages and develop their related skills; 3) Strengthen partnerships between healthcare providers and EBHV to increase referrals, retention, and improve CVH, and 4) Contribute to the development of a high-impact study design for the subsequent UH3 phase involving a multi-cohort protocol, harmonized interventions, measures and resources. For the subsequent UH3 phase, we propose a Hybrid Type 1 effectiveness-implementation trial in which we recruit 550 perinatal women who will be randomized to receive EBHV alone or EBHV enhanced with our lifestyle intervention to promote CVH. Our primary hypothesis is that, over an average of 36 months, EBHV+CVH (vs. EBHV alone) will result in more favorable maternal and child levels of the Life’s Simple 7 indicators. We will also examine key intervention moderators, focusing on social determinants of health, and mediators, including changes in the home environment, social support, CVH behaviors, and program adherence. Using the RE-AIM framework, we will determine reach, effectiveness, adoption, implementation, and maintenance of EBHV+CVH vs. EBHV alone. Other goals are to empower and reduce burnout among home visitors; develop skills of early-stage investigators, and propose innovative ancillary studies to enhance the scientific contributions. Our team is exceptionally well positioned for this research and includes established investigators with decades of experience conducting NIH funded research, outstanding early stage investigators, and EBHV sites from Central California and Rhode Island.
项目总结/文摘

项目成果

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Stephanie Hart Parade其他文献

Stephanie Hart Parade的其他文献

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{{ truncateString('Stephanie Hart Parade', 18)}}的其他基金

Healthy Hearts/ Corazones Saludables: Partnership to promote cardiovascular health in Hispanic and non-Hispanic mothers and children in US home visiting programs
Healthy Hearts/Corazones Saludables:在美国家访计划中合作促进西班牙裔和非西班牙裔母亲和儿童的心血管健康
  • 批准号:
    10618401
  • 财政年份:
    2022
  • 资助金额:
    $ 59.53万
  • 项目类别:
Core C: Community Collaborative Core
核心C:社区协作核心
  • 批准号:
    10686042
  • 财政年份:
    2021
  • 资助金额:
    $ 59.53万
  • 项目类别:
Core C: Vulnerable Populations Core
核心 C:弱势群体核心
  • 批准号:
    10478814
  • 财政年份:
    2021
  • 资助金额:
    $ 59.53万
  • 项目类别:
Core C: Vulnerable Populations Core
核心 C:弱势群体核心
  • 批准号:
    10090778
  • 财政年份:
    2021
  • 资助金额:
    $ 59.53万
  • 项目类别:
Embedding Mental Health Consultation Within Prenatal Home Visiting to Prevent Child Maltreatment and Violence Exposure
将心理健康咨询纳入产前家访,防止儿童遭受虐待和暴力
  • 批准号:
    10237847
  • 财政年份:
    2019
  • 资助金额:
    $ 59.53万
  • 项目类别:
Embedding Mental Health Consultation Within Prenatal Home Visiting to Prevent Child Maltreatment and Violence Exposure
将心理健康咨询纳入产前家访,防止儿童遭受虐待和暴力
  • 批准号:
    10023242
  • 财政年份:
    2019
  • 资助金额:
    $ 59.53万
  • 项目类别:
Longitudinal examination of DNA methylation in maltreated children
受虐待儿童 DNA 甲基化的纵向检查
  • 批准号:
    9572656
  • 财政年份:
    2018
  • 资助金额:
    $ 59.53万
  • 项目类别:
Longitudinal examination of DNA methylation in maltreated children
受虐待儿童 DNA 甲基化的纵向检查
  • 批准号:
    10470138
  • 财政年份:
    2018
  • 资助金额:
    $ 59.53万
  • 项目类别:
Longitudinal examination of DNA methylation in maltreated children
受虐待儿童 DNA 甲基化的纵向检查
  • 批准号:
    10002336
  • 财政年份:
    2018
  • 资助金额:
    $ 59.53万
  • 项目类别:

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