Radiation Mitigators Targeting Regulated Necrosis Pathways of Parthanatos Pyroptosis
针对帕塔纳托细胞焦亡调节坏死途径的辐射缓解剂
基本信息
- 批准号:10436895
- 负责人:
- 金额:$ 47.54万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2020
- 资助国家:美国
- 起止时间:2020-07-08 至 2023-02-28
- 项目状态:已结题
- 来源:
- 关键词:AcuteAntibodiesAntigensApoptosisApoptoticBacteriaBloodCASP1 geneCell DeathCell Membrane PermeabilityCell NucleusCell membraneCellsCessation of lifeChemotactic FactorsComputer ModelsDataDevelopmentDiseaseDoseEffectivenessEpithelial CellsEventExposure toFree RadicalsFundingGenerationsGoalsHematopoieticIL18 geneIn VitroInfectionInflammasomeInflammatoryInflammatory ResponseInterleukin-1 ReceptorsInterleukin-1 betaInterleukin-18IntestinesIonizing radiationKnowledgeLinkLipidsMediatingMedicalMitochondriaMitochondrial ProteinsMolecularNecrosisNuclear RadiologyNuclear TranslocationNuclear WarfareOuter Mitochondrial MembraneOxidation-ReductionOxidesParticipantPathogenesisPathogenicityPathway interactionsPhospholipidsPoly(ADP-ribose) PolymerasesProductionProliferatingProteinsRadiationRadiation AccidentsRadiation InjuriesRadiation exposureRadioactiveReactive Oxygen SpeciesRecoveryRoleSignal PathwaySignal TransductionStreamStressStructure-Activity RelationshipSyndromeTestingTherapeuticTissuesWaterWhole-Body Irradiationanakinraapoptosis inducing factorbaseclinically translatablecytokinedesigneffectiveness evaluationgastrointestinal epitheliumimprovedin vivo Modelinhibitorinterestirradiationlipid biosynthesislipid mediatorlipidomicsnovelnovel therapeuticsoxidationpathogenprogramsradiation mitigationradiation mitigatorradiological attackresponsesmall molecule inhibitortrafficking
项目摘要
No abstract provided
未提供摘要
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Hülya Bayir其他文献
Hülya Bayir的其他文献
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{{ truncateString('Hülya Bayir', 18)}}的其他基金
Oxidative Lipidomics in Pediatric Traumatic Brain Injury
氧化脂质组学在小儿创伤性脑损伤中的应用
- 批准号:
10844023 - 财政年份:2023
- 资助金额:
$ 47.54万 - 项目类别:
Radiation Mitigators Targeting Regulated Necrosis Pathways of Parthanatos Pyroptosis
针对帕塔纳托细胞焦亡的调节性坏死途径的辐射缓解剂
- 批准号:
10838232 - 财政年份:2023
- 资助金额:
$ 47.54万 - 项目类别:
Radiation Mitigators Targeting Regulated Necrosis Pathways of Parthanatos Pyroptosis
针对帕塔纳托细胞焦亡调节坏死途径的辐射缓解剂
- 批准号:
10625932 - 财政年份:2020
- 资助金额:
$ 47.54万 - 项目类别:
Druggable Mitochondrial Targets for Treatment of Cerebral Ischemia
用于治疗脑缺血的可药物线粒体靶点
- 批准号:
10592289 - 财政年份:2020
- 资助金额:
$ 47.54万 - 项目类别:
Druggable Mitochondrial Targets for Treatment of Cerebral Ischemia
用于治疗脑缺血的可药物线粒体靶点
- 批准号:
10090670 - 财政年份:2020
- 资助金额:
$ 47.54万 - 项目类别:
Druggable Mitochondrial Targets for Treatment of Cerebral Ischemia
用于治疗脑缺血的可药物线粒体靶点
- 批准号:
10328870 - 财政年份:2020
- 资助金额:
$ 47.54万 - 项目类别:
Radiation Mitigators Targeting Regulated Necrosis Pathways of Parthanatos Pyroptosis
针对帕塔纳托细胞焦亡调节坏死途径的辐射缓解剂
- 批准号:
10212243 - 财政年份:2020
- 资助金额:
$ 47.54万 - 项目类别:
Mitochondria-Targeted Redox Therapy for Cerebral Ischemia in the Developing Brain
线粒体靶向氧化还原疗法治疗发育中大脑缺血
- 批准号:
8820302 - 财政年份:2014
- 资助金额:
$ 47.54万 - 项目类别:
Mitochondria-Targeted Redox Therapy for Cerebral Ischemia in the Developing Brain
线粒体靶向氧化还原疗法治疗发育中大脑缺血
- 批准号:
9193104 - 财政年份:2014
- 资助金额:
$ 47.54万 - 项目类别:
Mitochondria-Targeted Redox Therapy for Cerebral Ischemia in the Developing Brain
线粒体靶向氧化还原疗法治疗发育中大脑缺血
- 批准号:
8994750 - 财政年份:2014
- 资助金额:
$ 47.54万 - 项目类别:
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