University of Texas Prevention Research Center

摘要 癌症是得克萨斯州男性和女性的第二大死因，发病率和死亡率都很高 每100,000人中分别为147.4和158.8人。非洲裔美国人和西班牙裔美国人的比例要高得多 一些癌症的发病率和与癌症相关的健康差距。在德克萨斯州，一个高度多样化的州，筛选和 预防行为仍然低于国家对居住在 无论是农村还是城市环境。值得注意的是，德克萨斯州在全国结直肠癌筛查中排名第48位，在 接种人乳头瘤病毒疫苗。我们的长期目标是减少与癌症相关的发病率、死亡率和健康差距。 在德克萨斯州城乡的非裔美国人和西班牙裔美国人中。 德克萨斯大学预防研究中心(UTPRC)计划的主题是“加速癌症” 控制以减少健康差距。“UTPRC的使命是增加循证医学的使用 社区和医疗保健环境中的癌症控制干预、政策和指南 学术、公共卫生和社区合作伙伴关系以实践为基础， 社区参与的预防研究、研究翻译和教育。拟议的UTPRC 包括将促进培训、研究翻译和社区参与的核心，并确保快速 UTPRC研究成果和产品的有效沟通。我们将创建一个社区网络 得克萨斯州各地的合作伙伴称为PACE(合作伙伴加速癌症控制证据)，以期在 城乡少数民族社区。我们将在六年内使用德克萨斯大学公共卫生学院的区域基础设施 得克萨斯州周围地区，以确保接触到弱势群体，并加快扩大和推广有效的 程序。我们还提出了一个创新的核心研究项目，测试将 加强癌症控制，减少与癌症相关的健康差距。 UTPRC将通过以下方式推进预防研究和实施科学领域：培训公众 卫生专业人员和社区合作伙伴，让社区合作伙伴参与务实的预防和 实施研究，评估实施战略的效力和成本效益 更多地使用循证癌症控制干预措施，并在 得克萨斯州和美国。我们将继续通过长期参与 主题网络。最终，拟议中的中华人民共和国将推进实施和预防领域。 减少德克萨斯州脆弱人群中癌症负担和健康差距的科学。

Abstract Cancer is the second leading cause of death among men and women in Texas with incidence and mortality rates of 147.4 and 158.8 per 100,000, respectively. African Americans and Hispanics have significantly higher rates of some cancers and experience cancer-related health disparities. In Texas, a highly diverse state, screening and prevention behaviors remain below national recommendations for African American and Hispanics living in both rural and urban settings. Notably, Texas ranks 48th in colorectal cancer screening nationwide and 47th for HPV vaccination. Our long-term goal is to decrease cancer-related morbidity and mortality and health disparities among African Americans and Hispanics in urban and rural settings in Texas. The proposed University of Texas Prevention Research Center's (UTPRC) theme is, “Accelerating Cancer Control to Decrease Health Disparities.” The mission of the UTPRC is to increase the use of evidence-based cancer control interventions, policies, and guidelines in communities and healthcare settings through a collaboration of academic, public health, and community partnerships engaged in practice-based, community-engaged prevention research, research translation, and education. The proposed UTPRC includes cores that will advance training, research translation, and community engagement, and ensure rapid and effective communication of UTPRC research results and products. We will create a network of community partners across Texas called PACE (Partners Accelerating Cancer Control Evidence) to target cancer control in urban and rural minority communities. We will use UT School of Public Health Regional infrastructure in six areas around Texas to ensure access to vulnerable populations and accelerate scale up and spread of effective programs. We also propose an innovative core research project testing new implementation strategies that link communities and healthcare settings to increase cancer control and reduce cancer-related health disparities. The UTPRC will advance the field of prevention research and implementation science by: training public health professionals and community partners, engaging community partners in pragmatic prevention and implementation research, evaluating the effectiveness and cost effectiveness of implementation strategies on increased use of evidence-based cancer control interventions, and disseminating effective interventions across Texas and the U.S. We will continue to collaborate with other PRCs through our long-standing participation in thematic networks. Ultimately, the proposed PRC will advance the field of implementation and prevention science to reduce cancer burden and health disparities among vulnerable populations in Texas.