University of Texas Prevention Research Center

摘要 癌症是德克萨斯州男性和女性的第二大死亡原因， 分别为每10万人147.4和158.8人。非洲裔美国人和西班牙裔美国人的发病率明显更高 某些癌症的发病率，并经历与癌症相关的健康差异。在德克萨斯州，一个高度多样化的州， 预防行为仍然低于生活在非洲裔美国人和西班牙裔美国人的国家建议。 农村和城市环境。值得注意的是，德克萨斯州在全国结直肠癌筛查中排名第48位， HPV疫苗。我们的长期目标是减少与癌症有关的发病率和死亡率以及健康差距 在德克萨斯州的城市和农村地区的非洲裔美国人和西班牙裔美国人中。 德克萨斯大学预防研究中心（UTPRC）的主题是“加速癌症”。 控制以减少健康差距。”UTPRC的使命是增加循证医学的使用， 癌症控制干预措施，政策和指导方针，在社区和医疗机构，通过一个 学术，公共卫生和社区伙伴关系的合作， 社区参与的预防研究、研究翻译和教育。拟议的UTPRC 包括促进培训、研究翻译和社区参与并确保快速的核心 以及UTPRC研究成果和产品的有效沟通。我们将创建一个社区网络 德克萨斯州的合作伙伴称为PACE（合作伙伴加速癌症控制证据）， 城乡少数民族社区。我们将使用公共卫生区域基础设施的UT学校在六个 德克萨斯州周边地区，以确保弱势群体的访问，并加快扩大和传播有效的 程序.我们还提出了一个创新的核心研究项目，测试新的实施战略， 社区和医疗机构，以增加癌症控制和减少癌症相关的健康差距。 UTPRC将通过以下方式推进预防研究和实施科学领域： 卫生专业人员和社区合作伙伴，让社区合作伙伴参与务实的预防工作， 实施研究，评估实施战略的有效性和成本效益， 更多地使用循证癌症控制干预措施，并在全国范围内传播有效的干预措施 我们将继续通过我们长期参与的活动与其他中国合作， 专题网络。最终，拟议的项目审查委员会将推动执行和预防领域的工作， 科学，以减少癌症负担和健康差距在德克萨斯州的弱势群体。

Abstract Cancer is the second leading cause of death among men and women in Texas with incidence and mortality rates of 147.4 and 158.8 per 100,000, respectively. African Americans and Hispanics have significantly higher rates of some cancers and experience cancer-related health disparities. In Texas, a highly diverse state, screening and prevention behaviors remain below national recommendations for African American and Hispanics living in both rural and urban settings. Notably, Texas ranks 48th in colorectal cancer screening nationwide and 47th for HPV vaccination. Our long-term goal is to decrease cancer-related morbidity and mortality and health disparities among African Americans and Hispanics in urban and rural settings in Texas. The proposed University of Texas Prevention Research Center's (UTPRC) theme is, “Accelerating Cancer Control to Decrease Health Disparities.” The mission of the UTPRC is to increase the use of evidence-based cancer control interventions, policies, and guidelines in communities and healthcare settings through a collaboration of academic, public health, and community partnerships engaged in practice-based, community-engaged prevention research, research translation, and education. The proposed UTPRC includes cores that will advance training, research translation, and community engagement, and ensure rapid and effective communication of UTPRC research results and products. We will create a network of community partners across Texas called PACE (Partners Accelerating Cancer Control Evidence) to target cancer control in urban and rural minority communities. We will use UT School of Public Health Regional infrastructure in six areas around Texas to ensure access to vulnerable populations and accelerate scale up and spread of effective programs. We also propose an innovative core research project testing new implementation strategies that link communities and healthcare settings to increase cancer control and reduce cancer-related health disparities. The UTPRC will advance the field of prevention research and implementation science by: training public health professionals and community partners, engaging community partners in pragmatic prevention and implementation research, evaluating the effectiveness and cost effectiveness of implementation strategies on increased use of evidence-based cancer control interventions, and disseminating effective interventions across Texas and the U.S. We will continue to collaborate with other PRCs through our long-standing participation in thematic networks. Ultimately, the proposed PRC will advance the field of implementation and prevention science to reduce cancer burden and health disparities among vulnerable populations in Texas.