Delaware Clinical and Translational Research ACCEL Program-BERD Core

特拉华州临床和转化研究 ACCEL 计划-BERD 核心

• 批准号: 10437681
• 负责人: Claudine Jurkovitz
• 金额: $ 84.9万
• 依托单位: UNIVERSITY OF DELAWARE
• 依托单位国家: 美国
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-09-25 至 2023-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10437681
• 关键词: Address; Area; Award; Big Data; Big Data to Knowledge; Bioinformatics; Biomedical Research; Biometry; Clinical; Clinical Informatics; Clinical Research; Collaborations; Communities; Complex; Consultations; Data; Data Scientist; Data Set; Delaware; E-learning; Epidemiologist; Epidemiology; Fostering; Funding; Genes; Grant; Health; Health Sciences; Healthcare; Healthcare Systems; Informatics; Infrastructure; Institutes; Institution; Institutional Review Boards; Knowledge; Medical; Medical Informatics; Methods; Partner in relationship; Pediatric Hospitals; Positioning Attribute; Protocols documentation; Research; Research Design; Research Institute; Research Personnel; Research Project Grants; Resources; Scientist; Series; Services; South Carolina; Translational Research; United States National Institutes of Health; Universities; Visualization; bioinformatics resource; biomedical informatics; complex data; cost effectiveness; data management; educational atmosphere; epidemiology study; experience; gene discovery; gene environment interaction; health care delivery; innovation; lectures; meetings; member; population health; programs; response; success

Abstract—BERD The Biostatistics, Epidemiology and Research Design (BERD) KCA of the Delaware-CTR ACCEL has been success- ful in meeting the original Specific Aims: providing consultations across ACCEL institutions, providing educational forums, developing methods, and supporting the Big Data Pilot grants. BERD has skilled, experienced epidemiolo- gists, biostatisticians, bioinformaticians, and biomedical informaticians forming a critical mass of scientists to sup- port clinical and translational projects. This success has been fostered by close collaboration across the four current ACCEL partner institutions: The University of Delaware (UD), the Nemours/Alfred I. DuPont Hospital for Children (Nemours), Christiana Care Health System (CCHS), the Medical University of South Carolina (MUSC). We look forward to welcoming Delaware State University (DSU) to BERD as part of this renewal. Each ACCEL institution has organizational programs with expertise in epidemiology, biostatistics and bioinformatics, MUSC has an established CTSA, the South Carolina Clinical and Translational Research Institute (SCTR). ACCEL in general and BERD in particular have collaborated closely with SCTR. BERD also functions closely with the Value Institute (VI) at CCHS, and the newly established Biomedical Research Infor-matics Center (BRIC) at Nemours. The VI is an innovative research institute for studying healthcare delivery as well as translational research. BRIC is a team of bioinformati- cians, data scientists, and developers formed in response to the expanding need for a bridge facility between research and clinical informatics. In addition, UD and DSU both have considerable infrastructure and expertise in bioinfor- matics. The scientists at the BRIC, SCTR, VI, UD and DSU add to the overall strength of ACCEL and BERD in further developing infrastructure and the critical mass of investigators to support projects of importance concerning health and healthcare in Delaware. BERD has also collaborated closely with the other ACCEL KCAs and a number of BERD scientists are members of multiple KCAs, promoting component interconnectedness. The Specific Aims of BERD are to: 1: Provide consultative services for clinical, translational and population health sciences at ACCEL institutions. Consultative services include epidemiology, biostatistics, research design, data management, and bio- and medical informatics. 2: Develop new, innovative, and quantitative methods in biostatistics, epidemiology, and bioinformatics. 3: Foster a learning environment through educational offerings in BERD scientists’ areas of expertise. 4: Leverage the deep biomedical informatics and bioinformatics resources across the ACCEL institu-tions to support new and extended research projects addressing critical healthcare needs in Delaware. We are well-positioned to provide such support, building on the successful infrastructure established over the first AC-CEL award period, including develop- ing external collaborations with multiple IDeA-funded centers, becoming an integral part of large-scale external data networks such as PEDSnet and NIH Big Data to Knowledge (BD2K), and internally funding Big Data interdisciplin- ary pilot grants.

摘要-BERD 特拉华州CTR ACCEL的生物统计学、流行病学和研究设计（BERD）KCA取得了成功- 充分满足最初的具体目标：在ACCEL机构提供咨询，提供教育 论坛，开发方法，并支持大数据试点赠款。BERD拥有熟练、经验丰富的流行病学专家， 科学家，生物统计学家，生物信息学家和生物医学信息学家形成了一个科学家的临界质量，以支持， 港口临床和翻译项目。这一成功得益于目前四个机构之间的密切合作。 ACCEL合作机构：特拉华州大学（UD），内穆尔/阿尔弗雷德I。杜邦儿童医院 （Nemours）、Christiana Care Health System（CCHS）、南卡罗来纳州医科大学（MUSC）。我们看起来 期待欢迎特拉华州州立大学（DSU）BERD作为这一更新的一部分。每个ACCEL机构都有 MUSC拥有流行病学，生物统计学和生物信息学方面的专业知识， CTSA，南卡罗来纳州临床和转化研究所（SCTR）。一般情况下为ACCEL， 特别是与SCTR密切合作。BERD还与CCHS的价值研究所（VI）密切合作， 以及新成立的内穆尔生物医学研究信息中心（BRIC）。VI是一种创新的 研究机构，研究医疗保健服务以及转化研究。金砖四国是一个生物信息团队， 科学家、数据科学家和开发人员组成，以应对研究与开发之间日益增长的桥梁设施需求。 临床信息学。此外，UD和DSU在生物信息领域都拥有相当的基础设施和专业知识， matics。金砖四国，SCTR，VI，UD和DSU的科学家进一步增加了ACCEL和BERD的整体实力 发展基础设施和足够数量的调查人员，以支持与卫生有关的重要项目 在特拉华州的医疗保健BERD还与其他ACCEL KCA和一些BERD密切合作， 科学家是多个KCA的成员，促进了组件的互连性。BERD的具体目标是 1.在ACCEL机构提供临床、转化和人口健康科学咨询服务。 咨询服务包括流行病学、生物统计学、研究设计、数据管理以及生物和医学 信息学. 2.在生物统计学、流行病学和生物信息学方面开发新的、创新的和定量的方法。 3：通过在BERD科学家的专业领域提供教育，营造学习环境。4：杠杆 深入的生物医学信息学和生物信息学资源在整个ACCEL机构，以支持新的， 扩展研究项目，解决特拉华州的关键医疗保健需求。我们有能力提供这样的 支持，建立在第一个AC-CEL合同期内成功建立的基础设施上，包括开发- 与多个IDEA资助的中心进行外部合作，成为大规模外部数据的组成部分 网络，如PEDSnet和NIH大数据知识（BD 2K），并在内部资助大数据跨学科， 空军飞行员赠款。