Integrated Biobanking Shared Resource

项目摘要：综合生物库共享资源(IBSR) 综合生物库共享资源的目的是通过以下方式提供对生物检疫的访问 协调全面和有针对性的生物样品采购，以及相关的专业知识和技术 加强DAN的基础、翻译和临床癌症生物样品研究活动的资源 L.Duncan综合癌症中心。获得这样的资源对基于生物胺的癌症至关重要 调查。该共享资源(SR)是先前的人类组织获取和病理学的合并 (HTAP)和人口科学生物库(PSB)SR整合为单一的综合生物银行SR(IBSR)。 这是HTAP和PSB SRS多年来密切工作关系的自然结果。 HTAP和PSB SRS的合并将使我们能够进一步将我们的业务整合到一个共同的管理中 结构。共享资源人员在病理学、流行病学、 生物菌剂的收购和加工，银行的维护和分销。此外，还对人员进行培训 在提供的各种技术服务中，包括外周血单核细胞制备、DNA 提取，常规组织学服务，冰冻切片，组织微阵列构建，免疫组织化学， 组织微阵列扫描和多路图像分析。我们还提供专家的病理咨询。 人类组织标本和小鼠模型的病理学家，以及风险因素问卷的开发 和收藏。

PROJECT SUMMARY: Integrated Biobanking Shared Resource (IBSR) The purpose of the Integrated Biobanking Shared Resource is to provide access to biospecimens by coordinated general and targeted biospecimen acquisition along with relevant expertise and technical resources to enhance basic, translational and clinical cancer biospecimen-based research activities at the Dan L. Duncan Comprehensive Cancer Center. Access to such resources is critical for biospecimen-based cancer investigations. This Shared Resource (SR) is a merger of the prior Human Tissue Acquisition and Pathology (HTAP) and the Population Sciences Biorepository (PSB) SRs into a single Integrated Biobanking SR (IBSR). This is a natural outgrowth of the close working relationship of the HTAP and PSB SRs over many years. Merger of HTAP and PSB SRs will allow us to further integrate our operations within a common management structure. The Shared Resource personnel have extensive experience in pathology, epidemiology, biospecimen acquisition and processing, bank maintenance and distribution. In addition, personnel are trained in the various technical services offered including peripheral blood mononuclear cell preparation, DNA extraction, routine histology services, frozen sections, tissue microarray construction, immunohistochemistry, tissue microarray scanning, and multiplex image analysis. We also provide pathology consultation by expert pathologists for both human tissue specimens and mouse models, and risk factor questionnaire development and collection.