Development of a Standardized Electronic Treatment Plan Builds for NCI-supported Clinical Trials Year 2

医疗机构利用电子医疗记录(EHR)为患者提供精心治疗的支持 计划，特别是与肿瘤学疗法有关的计划。这些治疗计划传统上是在 符合各自机构的内容专家、EHR配置和当地标准指南 关爱。许多研究性药物的研究也包含复杂的治疗方案， 在实施之前要经过相同的工作流程和审查。这些研究中的许多都是实施的 几个卫生机构，包括由国家癌症研究所(NCI)发起的机构。多站点 研究有一种内在的需要，即跨地点标准化，以减少差异。然而，因为 各机构利用当地的EHR配置、护理标准和内容专家来创建这些研究 治疗计划从头开始，参与地点之间存在不必要的研究差异。此外， 由于每个卫生系统需要识别疾病、研究 和EHR建立专家，他们可以投入时间进行研究、协作和实施。这样做的目的是 该项目是开发一个标准化NCI支持的EHR治疗计划的联盟，以缓解 研究参与站点的变化和实施时间。项目计划涉及建立一个 十大癌症研究联盟中的专家小组委员会。这 该联盟由大量参与NCI资助的研究的成员组成。成员 来自该联盟的专家将包括NCI相关研究、EHR构建创建以及 研究建议和信息学操作。该小组将定期召开会议，以比较以前的NCI 在各自的电子病历中赞助的治疗计划，以制定商定的创建NCI的标准 电子病历中的协议。然后将利用这些标准来创建用于参与的治疗计划模板 各机构将整合到各自的电子健康记录系统中。分析成功实施的措施 将与时间相关的数据涉及从请求、IRB最初批准到研究的实施持续时间 激活，以及与模板的易用性和解释相关的调查数据。该财团将审查 这些数据定期用于改进和可行性，以继续工作，规范治疗计划。这 工作将在参与的EHR和NCI成员之间分担。

Healthcare institutions utilize electronic healthcare records (EHR) to support patients with elaborate treatment plans, specifically those related to oncology regimens. These treatment plans traditionally are created in accordance to the respective institutions’ content expert, EHR configuration, and local guidelines for standard of care. Many research studies with investigational agents also contain complex treatment regimens which undergo the same workflow and scrutiny before implementation. Many of these studies are implemented across several health institutions, including those initiated by the National Cancer Institute (NCI). Multisite studies have an inherent need to be standardized across sites to reduce variation. However, because institutions utilize local EHR configuration, standards of care, and content experts to create these study treatment plans from scratch, unnecessary study variations between participating site cans exist. Furthermore, delay in study implementation may exist as a result of each health system’s need to identify disease, study, and EHR build experts who can commit time for study collaboration and implementation. The goal of this project is to develop a consortium for standardizing NCI supported EHR treatment plans to alleviate study variation and time-to-implementation for participating sites. The project plan involves establishing a subcommittee of experts within a pre-existing group known as the Big Ten Cancer Research Consortium. This consortium consists of members with significant participation in NCI supported research studies. Members from this consortium will include experts in NCI-related studies, EHR build creation, as well as management in research proposals and informatics operations. This group will convene regularly to compare previous NCI sponsored treatment plans within their respective EHR to develop agreed upon standards for creating NCI protocols in the EHR. These standards will then be utilized to create treatment plan templates for participating institutions to integrate within their respective EHR systems. Measures to analyze successful implementation will be time related data concerned with duration of implementation from request, initial IRB approval to study activation, and survey data related to the template’s ease of use and interpretation. The consortium will review these data regularly for improvement and feasibility to continue work in standardizing treatment plans. This work will be shared among participating EHR and NCI members.