Development of Hollow-fibre Bioreactor Technology (HFB) to enable resource-efficient cultivated meat production
开发中空纤维生物反应器技术 (HFB),实现资源高效型养殖肉生产
基本信息
- 批准号:10074909
- 负责人:
- 金额:$ 96.42万
- 依托单位:
- 依托单位国家:英国
- 项目类别:Collaborative R&D
- 财政年份:2023
- 资助国家:英国
- 起止时间:2023 至 无数据
- 项目状态:未结题
- 来源:
- 关键词:
项目摘要
For years, meat has been the main source of protein globally. However, the health, environmental and animal welfare concerns of traditional meat production have driven the search for alternatives. Cultivated meat products represent an incredible opportunity to provide an alternative (and complementary) method to traditional farming methods to keep up with the growing demand of the global population.It is the alternative that would meet customer's expectations the most accurately. It frees up land and requires less water than livestock farming. Cultivated meat could address the protein shortage for a global population projected to reach 9.5bn by 2050\. However, the cultivated meat industry is still in its infancy and although processes have been tested and validated, scaling the technology at low-cost remains an immense challenge.This consortium brings together innovative tissue engineering and bioreactor specialist, Cellular Agriculture (CellAg), and Campden BRI (CBRI), the UK's largest independent food and drinks R&D organisation. This project intends to optimise, test and validate the scalability of hollow-fibre bioreactors (HFB) to produce cultivated meat products. HFB has significant advantages compared to current state-of-the-art bioreactors (e.g.stirred-tank/fixed-bed) with increased cell density, compact design, cost-efficiency and lower emissions which would unlock the commercial viability of cultivated meat production.Building on proof-of-concept work led by CellAg, the consortium will develop an HFB system prototype demonstrator that will be optimised at CBRI's facilities. CBRI will then collaborate with CellAg to test production samples and develop food quality, safety, regulatory, economic and sustainability assessments.This project will enable CellAg to further develop and test the HFB to rapidly commercialise their technology post-project to food manufacturers and cultivated meat companies. This project will put CBRI at the forefront of innovative food research by developing a cutting-edge cultivated meat production system. The knowledge acquired during the project will also be productised by CBRI in the form of e-learning courses and supporting services.
多年来,肉类一直是全球蛋白质的主要来源。然而,传统肉类生产对健康、环境和动物福利的担忧推动了对替代品的寻找。栽培肉制品代表着一个令人难以置信的机会,可以提供传统耕作方法的替代(和补充)方法,以跟上全球人口日益增长的需求。这是最准确地满足客户期望的替代方法。与畜牧业相比,它释放了土地,需要的水更少。栽培肉类可以解决全球人口的蛋白质短缺问题,预计到2050年,全球人口将达到95亿。然而,培育肉类行业仍处于初级阶段,尽管工艺已经过测试和验证,但以低成本推广这项技术仍然是一个巨大的挑战。该联盟将创新的组织工程和生物反应器专家细胞农业(CellAg)和英国最大的独立食品和饮料研发组织Campden BRI(CBRI)结合在一起。该项目旨在优化、测试和验证中空纤维生物反应器(HFB)生产养殖肉制品的可扩展性。与目前最先进的生物反应器(如搅拌槽/固定床)相比,HFB具有显著的优势,细胞密度更高,设计紧凑,成本效益更高,排放更低,这将释放培养肉类生产的商业可行性。在CellAg领导的概念验证工作的基础上,该联盟将开发HFB系统原型演示器,该原型将在CBRI的设施中进行优化。然后,CBRI将与CellAg合作测试生产样本,并开发食品质量、安全、监管、经济和可持续性评估。该项目将使CellAg能够进一步开发和测试HFB,以便在项目结束后迅速将其技术商业化,供食品制造商和培育肉类公司使用。该项目将通过开发尖端的栽培肉类生产系统,使CBRI处于创新食品研究的前沿。在该项目期间获得的知识还将由CBRI以电子学习课程和支助服务的形式加以利用。
项目成果
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其他文献
吉治仁志 他: "トランスジェニックマウスによるTIMP-1の線維化促進機序"最新医学. 55. 1781-1787 (2000)
Hitoshi Yoshiji 等:“转基因小鼠中 TIMP-1 的促纤维化机制”现代医学 55. 1781-1787 (2000)。
- DOI:
- 发表时间:
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- 影响因子:0
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LiDAR Implementations for Autonomous Vehicle Applications
- DOI:
- 发表时间:
2021 - 期刊:
- 影响因子:0
- 作者:
- 通讯作者:
吉治仁志 他: "イラスト医学&サイエンスシリーズ血管の分子医学"羊土社(渋谷正史編). 125 (2000)
Hitoshi Yoshiji 等人:“血管医学与科学系列分子医学图解”Yodosha(涉谷正志编辑)125(2000)。
- DOI:
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Effect of manidipine hydrochloride,a calcium antagonist,on isoproterenol-induced left ventricular hypertrophy: "Yoshiyama,M.,Takeuchi,K.,Kim,S.,Hanatani,A.,Omura,T.,Toda,I.,Akioka,K.,Teragaki,M.,Iwao,H.and Yoshikawa,J." Jpn Circ J. 62(1). 47-52 (1998)
钙拮抗剂盐酸马尼地平对异丙肾上腺素引起的左心室肥厚的影响:“Yoshiyama,M.,Takeuchi,K.,Kim,S.,Hanatani,A.,Omura,T.,Toda,I.,Akioka,
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