Community-Engaged Research on COVID-19 Testing Among Underserved and/or Vulnerable Populations Phase II

社区参与的针对服务不足和/或弱势群体的 COVID-19 检测研究第二阶段

• 批准号: 10447463
• 负责人: Marianna K Baum
• 金额: $ 110.56万
• 依托单位: FLORIDA INTERNATIONAL UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-01-01 至 2023-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10447463
• 关键词: Affect; Antibodies; Antibody Formation; Anxiety; Area; Attitude; Behavior; Belief; Black Populations; Black race; CLIA certified; COVID-19; COVID-19 disparity; COVID-19 pandemic; COVID-19 prevention; COVID-19 risk; COVID-19 stress; COVID-19 testing; COVID-19 vaccine; Caring; Case Fatality Rates; Cessation of life; Church; Clinic; Common Data Element; Communities; Community Outreach; Community Participation; Complex; Contact Tracing; County; Data; Data Analyses; Effectiveness; Environmental Risk Factor; Epidemic; Event; Florida; Follow-Up Studies; Goals; Health; Health Personnel; Healthcare; Hispanic; Hispanic Populations; Hospitalization; Hour; Incidence; Individual; Infection; Infrastructure; Interview; Knowledge; Laboratories; Leadership; Longitudinal Studies; Measurable; Mental Depression; Mental Health; Minority; Minority Groups; Neighborhoods; Nurses; Outcome; Participant; Phase; Physicians; Play; Population; Psyche structure; Public Health; Questionnaires; RADx Underserved Populations; Research; Resources; SARS-CoV-2 infection; SARS-CoV-2 transmission; Serology; Seroprevalences; Site; Social Conditions; Social status; Source; Surveys; Testing; Underserved Population; United States; Vaccination; Vaccines; Variant; Vulnerable Populations; base; community engaged research; community engagement; community organizations; community partnership; community transmission; data mining; ethnic minority; experience; fighting; follow-up; health disparity; health economics; hispanic community; improved; member; minority communities; minority health; minority healthcare; outreach; pandemic disease; phase 1 study; racial and ethnic; recruit; resilience; response; social health determinants; social vulnerability; testing uptake; trustworthiness; underserved community; uptake; vaccine acceptance; vaccine access; vaccine trial; vulnerable community

PROJECT SUMMARY The COVID-19 pandemic has caused unprecedented public health and economic consequences globally and in the United States. Long-standing social inequities have been magnified and vulnerable communities have been disproportionately burdened by the pandemic. In Miami-Dade County, Florida, where minority populations experience a high level of social vulnerability, Blacks and Hispanics are overrepresented in COVID-19 related hospitalizations and deaths compared to national rates. Further, Miami-Dade County continues to experience COVID-19 rates well above the state and national levels. Effective vaccines are now available, yet vaccination rates have been persistently lower among U.S. minorities, broadening disparities in COVID-19 outcomes. As such, expanded SARS-CoV-2 testing and vaccine acceptance is critical to mitigating community spread in underserved and vulnerable communities. In this application for Phase II of the RADx-UP project, we will apply the knowledge gained during Phase I to expand community outreach to increase testing and vaccine uptake in minority communities to decrease disparities that contribute to burden of COVID-19 in underserved and vulnerable populations. We propose to continue our RADx-UP community-engaged research by employing new recruitment strategies in conjunction with four community partners to increase reach of testing that include engaging faith leaders and minority health care providers, and placing our mobile testing (and vaccination) unit in church parking areas. We will also conduct a longitudinal study among participants who completed Phase I of the study to assess (a) changes in infection and vaccination status, (b) how the availability of vaccines affects attitudes, beliefs, and behaviors related to testing, (c) changes in SDoH and their impact on COVID-19 testing and vaccine uptake/hesitancy, and (d) the relationship between mental resilience, mental health, and testing and vaccine uptake/hesitancy, and (e) other RADx-UP common data elements. We will also conduct post-infection and post-vaccination studies on antibody production and subsequent infections. For the proposed Phase II application, we have partnered with new community organizations, including Keeping the Faith to Fight COVID-19, an organization of minority health care providers working with Black and Black Hispanic churches, and with the Community Engagement Alliance (CEAL) Against COVID-19 Disparities initiative. We are currently conducting RADx-UP Phase I with established infrastructure and community partnerships to accomplish the aims and enable rapid and measurable impact in access and uptake of SARS- CoV-2 testing by underserved and vulnerable populations. Our community partners have the resources to provide community engagement, public health mitigation, and follow-up care for cases who test positive. Our strategy includes Scientific and Community Advisory Boards; a mobile testing unit; a CLIA-licensed laboratory headed by the PI of this application; data mining and longitudinal approaches for data analyses; and a research team experienced in recruiting and retaining members of the communities targeted in this proposal.

项目总结