Coordinated Oral Health Promotion (CO-OP) Chicago Cohort Study

协调口腔健康促进 (CO-OP) 芝加哥队列研究

• 批准号: 10447658
• 负责人: MOLLY A MARTIN
• 金额: $ 107.39万
• 依托单位: UNIVERSITY OF ILLINOIS AT CHICAGO
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-07-08 至 2026-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10447658
• 关键词: 3 year old; Absenteeism; Address; Adverse effects; Affect; Affordable Care Act; Age; Behavior; Black Populations; Black race; COVID-19; Caregivers; Chicago; Child; Child Behavior; Child Rearing; Childhood; Clinical; Cohort Studies; Communities; Data; Data Collection; Data Sources; Dental; Dental Care; Dental Hygiene; Dental Plaque; Dental caries; Diet; Direct Costs; Disadvantaged; Disease; Enrollment; Ethnic Origin; Family; Fluorides; Frequencies; Funding; Future; General Anesthesia; Genetic; Grant; Health; Health Food; Health Insurance; Health Promotion; Health Services Accessibility; Health behavior; Healthcare; Hispanic; Hispanic Populations; Home; Individual; Intervention; Longitudinal cohort; Low income; Mediating; Medicaid; Minority Groups; Modeling; Morbidity - disease rate; National Institute of Dental and Craniofacial Research; Nutritional; Oral health; Pain; Participant; Patient Self-Report; Positioning Attribute; Prevalence; Preventive; Provider; Psychosocial Factor; Randomized Controlled Trials; Reporting; Research; Risk; Risk Factors; Schools; Sedation procedure; Subgroup; Surveys; Techniques; Testing; Time; Toothbrushing; Toothpaste; United States; Violence; Water fluoridation; Work; aged; arm; cognitive development; cohort; community intervention; community-level factor; cost; cost effective; demographics; effectiveness testing; experience; food security; health belief; health data; health disparity; health literacy; health related quality of life; healthcare community; high risk; improved; lens; lower income families; primary outcome; recruit; research and development; social; theories; therapy development

SUMMARY Caries prevalence, morbidity, and associated disparities in children have been well documented nationally and locally. Research now is trying to understand why these disparities persist. Caries risk for an individual is considered a combination of genetics and behaviors (diet, oral hygiene, and fluoride exposure). The Coordinated Oral Health Promotion (CO-OP) Chicago Cohort Study will use the social ecological theory lens to examine caries risk factors on multiple levels. CO-OP Chicago was previously funded by NIDCR to reduce oral health disparities in children. The original CO-OP Chicago study [UH2DE02583] established baseline estimates of tooth brushing behaviors and determined the feasibility of objective assessment of tooth brushing behaviors in the homes of high-risk children under the age of three years old. CO-OP Chicago [UH3DE025483] then recruited 420 child/caregiver dyads to participate in a two-arm, cluster-randomized controlled trial testing the effectiveness of a family-focused CHW oral health intervention to improve tooth brushing behaviors for young children. The primary outcome was caregiver-reported brushing frequency and observed plaque score at 12-months. At entry into the study, the mean child age was 21.5 months. Forty-two percent of participants described themselves as Black race, and 54% as Hispanic ethnicity. Most children (89%) had Medicaid health insurance. CO-OP Chicago collected a range of self-reported and observed oral health data as well as family psychosocial factors from these low-income families over one year. However, the study did NOT include a caries assessment. The proposed CO-OP Chicago Cohort Study will transition trial participants into a longitudinal cohort (minimum N=315) to determine multi-level predictors of oral health behaviors and caries risk in low-income, urban young children over time. The CO-OP Chicago Cohort Study uses the social ecologic model to organize oral health risk factors into individual (child), interpersonal (family), organizational (healthcare), and community domains. We will collect four additional years of data with data collection every six months that includes caregiver-reported and observed child oral health behaviors, dental plaque scores, diet, parenting styles, dental provider access, and social risk factors. We will also conduct two caries examinations on children at ages five and seven. Community-level data will be extracted from public data sources. Specific Aim 1 is to examine associations between child, family, healthcare, and community factors on young child home oral health behaviors (child brushing frequency and plaque score) over time. Specific Aim 2 is to examine associations between child, family, healthcare, and community factors on young child caries prevalence over time. Specific Aim 3 is to examine the mediating effects of child brushing frequency and plaque score on the prior identified risk factors associated with caries prevalence. An Exploratory Aim will determine the ability of plaque scores to predict risk of caries. These data will advance our understanding of caries risk factors and inform future research and intervention development.

摘要 儿童的龋齿患病率、发病率和相关的差异已经在全国范围内得到了很好的记录 本地的。现在的研究正在试图理解为什么这些差距持续存在。个人患龋齿的风险是 被认为是遗传和行为(饮食、口腔卫生和氟化物暴露)的组合。这个 协调口腔健康促进(CO-OP)芝加哥队列研究将使用社会生态学理论 镜片，在多个层面上检查龋齿危险因素。Co-op Chicago之前是由NIDCR资助的 减少儿童口腔健康差距。最初的芝加哥合作研究[UH2 DE02583]建立了 刷牙行为的基线估计和确定客观评估牙齿的可行性 3岁以下高危儿童家庭刷牙行为。芝加哥合作公寓 [UH3DE025483]然后招募了420名儿童/照顾者双方参加一项双臂随机分组试验 以家庭为中心的CHW口腔健康干预改善牙齿效果的对照试验 幼儿的刷牙行为。主要结果是照顾者报告的刷牙频率和 观察12个月时的斑块评分。在进入研究时，儿童的平均年龄为21.5个月。四十二个 %的参与者称自己是黑人种族，54%的人称自己是西班牙裔种族。大多数儿童 (%)有医疗补助医疗保险。Co-op Chicago收集了一系列自我报告和观察的口头报告 这些低收入家庭一年多来的健康数据以及家庭心理社会因素。然而， 这项研究没有包括龋齿评估。拟议的CO-OP芝加哥队列研究将过渡 试验参与者进入纵向队列(最小N=315)，以确定口腔运动的多水平预测因素 随着时间的推移，低收入城市幼儿的健康行为和龋齿风险。芝加哥合作公寓 队列研究使用社会生态模型将口腔健康危险因素组织到个体(儿童)中， 人际(家庭)、组织(医疗保健)和社区领域。我们会再收集四个 多年的数据，每六个月收集一次数据，包括照顾者报告的和观察到的儿童口腔 健康行为、牙菌斑评分、饮食、父母教养方式、牙科提供者的可获得性以及社会风险因素。 我们还将为5岁和7岁的儿童进行两次龋齿检查。社区级别的数据将是 从公共数据源中提取。具体目标1是检查儿童、家庭、 卫生保健和社区因素对幼儿家庭口腔健康行为的影响(儿童刷牙频率和 斑块分数)随时间推移。具体目标2是检查儿童、家庭、医疗保健和 社区因素对幼儿患龋率随时间的影响具体目标3是检查调解 儿童刷牙频率和菌斑评分对先前已确定的与龋齿相关的危险因素的影响 流行率。一个探索性的目标将决定斑块评分预测龋齿风险的能力。这些数据 将促进我们对龋病危险因素的了解，并为未来的研究和干预发展提供信息。