GluSens - Advancing Bioprocessing with Single-Use Glucose Sensors

GluSens - 利用一次性葡萄糖传感器推进生物加工

• 批准号: 10076576
• 金额: $ 38.04万
• 依托单位: CARBOMETRICS LIMITED
• 依托单位国家: 英国
• 项目类别: Collaborative R&D
• 财政年份: 2023
• 资助国家: 英国
• 起止时间: 2023 至 无数据
• 项目状态: 未结题
• 来源: https://gtr.ukri.org/projects?ref=10076576
• 关键词: GluSens; Advancing; Bioprocessing; Single; Use

The project at hand constitutes an ambitious but highly achievable endeavour to revolutionize the field of bioprocessing, specifically in the realm of biological therapeutics and vaccines development. Spearheaded by Carbometrics and PyroScience, the objective is to synthesize a pioneering single-use glucose sensor, which can perform non-intrusive, efficient monitoring of glucose levels, an innovation that will transcend current methodologies.In the contemporary sphere of bioprocessing, monitoring glucose levels necessitates a disruptive intervention, akin to drawing a blood sample to measure sugar levels in the human body. This process invariably jeopardizes the integrity of the bioprocessing environment, leaving it susceptible to contamination. The proposed sensor, however, will possess the unique ability to quantify glucose levels through the non-invasive scanning of the reaction vessel walls, an unprecedented advancement in this field.The significance of such an innovation cannot be overstated. Glucose, being an essential nutrient for cell growth, requires precise monitoring to ensure optimal productivity and efficiency in the bioprocessing ecosystem. With the proposed sensor, the industry will gain the equivalent of a reliable, precise oven thermometer, facilitating the "baking" process without the risk of interfering with the environmental conditions.At the heart of this sensor is a bespoke molecule, designed to bind to glucose and thereby enable the sensor to "detect" its levels. This molecule has already been subjected to rigorous testing and validation, demonstrating promising results in various applications.Moreover, the proposed single-use sensor resonates with the contemporary paradigm of sustainability, addressing the global imperative to conserve water, energy, and overall resources. In this respect, the sensor will be positioned at the nexus of technological advancement and ecological responsibility.This remarkable project envisages the development of a first-of-its-kind, user-friendly, and environmentally conscious glucose sensor. Its successful realization promises to usher in a new era of safe, efficient, and sustainable bioprocessing, redefining how we produce indispensable medicines and vaccines.

目前的项目是一项雄心勃勃但高度可实现的努力，旨在彻底改变生物加工领域，特别是生物治疗和疫苗开发领域。由Carbometrics和PyroScience牵头，目标是合成一种开创性的一次性葡萄糖传感器，它可以对葡萄糖水平进行非侵入性的有效监测，这是一项超越当前方法的创新。在当代生物处理领域，监测葡萄糖水平需要破坏性干预，类似于抽取血液样本来测量人体中的血糖水平。这一过程不可避免地危害生物加工环境的完整性，使其容易受到污染。然而，所提出的传感器将具有通过对反应容器壁的非侵入性扫描来量化葡萄糖水平的独特能力，这是该领域前所未有的进步。葡萄糖是细胞生长的必需营养素，需要精确监测，以确保生物加工生态系统的最佳生产力和效率。该传感器相当于一个可靠、精确的烤箱温度计，可以在不干扰环境条件的情况下促进“烘烤”过程。该传感器的核心是一种定制的分子，旨在与葡萄糖结合，从而使传感器能够“检测”其水平。该分子已经过严格的测试和验证，在各种应用中显示出良好的效果。此外，所提出的一次性传感器与当代可持续发展模式相呼应，解决了全球节约水资源、能源和整体资源的迫切需要。在这方面，该传感器将定位于技术进步和生态责任的结合点。这个了不起的项目设想开发一种首创的、用户友好的、环保的葡萄糖传感器。它的成功实现有望开创一个安全、高效和可持续的生物加工新时代，重新定义我们生产不可或缺的药物和疫苗的方式。