2/2 – Regional GEOHealth Hub Centered in Peru-U.S.

2/2 — 以秘鲁-美国为中心的区域 GEOHealth 中心

• 批准号: 10448128
• 负责人: William Checkley
• 金额: $ 30万
• 依托单位: EMORY UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-09-28 至 2027-02-28
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10448128
• 关键词: Air Pollution; Alzheimer' s Disease; Bolivia; COVID-19; Chile; Clinic; Collaborations; Disease; Doctor of Philosophy; Ecuador; Educational Status; Electronic Mail; Environmental Health; Faculty; Food Safety; Frontotemporal Dementia; Funding; Goals; Government; Government Agencies; Grant; Health; Letters; Link; Mentors; Meteorology; Neurology; Peru; Peruvian; Positioning Attribute; Publications; Research; Research Activity; Research Assistant; Research Personnel; Research Project Grants; Research Proposals; Research Training; Services; Short-Term Course; South American; Students; Training; Training Activity; United States National Institutes of Health; Universities; Work; base; hydrology; meetings; programs; responsible research conduct; skills; training opportunity; virtual

Project Summary/Abstract Our goal with this research training renewal application and the linked research proposal, submitted by our partners at the Cayetano Heredia University in Peru (UPCH), is to continue our activities as a research and training center for environmental health based in Lima, Peru, with links to Ecuador, Bolivia, and Chile. This application builds on a successful six-year NIH/Fogarty funded grant where we conducted environmental health research in Peru and built collaborative ties with academic and governmental partners. Our work in Peru has resulted in more than 20 publications and 200 trainees. We have maintained an exceptionally strong team of environmental health researchers from UPCH, Emory U, Johns Hopkins U, and Universidad de Chile (U. Chile). We have strengthened our collaborations with government agencies as the General Directorate of Environmental Health and Food Safety – DIGESA, the National Service of Meteorology and Hydrology - SENAHMI, The Ministry of the Environmental - MINAM, and the Ministry of Health – MINSA (see letters of support) We have developed a new relationship with a major Lima neurology clinic focused on Alzheimer’s disease and fronto-temporal dementia. Our multiple PI group, Drs. Gonzales and Hartinger at UPCH and Dr. William Checkley at JHU will take primarily responsibility for the research projects with the support of Dr. Steenland and others at Emory. Dr. Steenland will provide primary support for the work on Alzheimer’s disease and fronto-temporal dementia. We will include former and trainees as research assistants on the new U01 grant, working on the main projects of that grant, including the association of air pollution with cardiorespiratory disease, COVID-19, and Alzheimer’s disease and fronto-temporal dementia. The UPCH will coordinate all training activities in this proposal with the support of the team at U.Chile, who are well positioned leaders in the South American region. The training activities proposed will build on our prior work and will include: 1) funding for graduate programs (at the master and PhD levels) at the UPCH and with thesis mentors from Peru, US, and Chile 2) one-on-one mentoring to Peruvian investigators, and 3) short term courses in Peru, Chile, and the US focused on developing research skills relevant to our research activities, including our Alzheimer’s disease research project. Over the project period we anticipate short-term training for a minimum of 167 trainees, one-on-one training opportunities every year for 25 Peruvian investigators, master level training to 6 students, and PhD training for 3 students. All our training activities will include responsible conduct of research training adapted to the scientific context in Peru, and will include Peruvian faculty. We will evaluate our programs by determining whether our goals have been fulfilled during the grant period. We will coordinate our activities during annual hub meetings, and via email and virtual rooms as needed for the management of the activities.

项目摘要/摘要 我们在秘鲁卡耶塔诺·赫雷迪亚大学(UPCH)的合作伙伴提交了这份研究培训续签申请和相关研究提案，我们的目标是继续我们作为环境健康研究和培训中心的活动，总部设在秘鲁利马，并与厄瓜多尔、玻利维亚和智利建立联系。这项申请建立在一项成功的为期六年的NIH/Fogarty资助赠款的基础上，我们在秘鲁进行了环境健康研究，并与学术和政府合作伙伴建立了合作关系。我们在秘鲁的工作产生了20多份出版物和200名受训人员。我们维持着一支非常强大的环境健康研究团队，这些研究人员来自加州大学伯克利分校、埃默里大学、约翰霍普金斯大学和智利大学。我们加强了与环境卫生和食品安全总局(DIGESA)、国家气象和水文局(SENAHMI)、环境部(MINAM)和卫生部(见支持函)等政府机构的合作。我们与利马一家主要的神经科诊所发展了新的关系，专注于阿尔茨海默氏症和额颞痴呆。我们的多重PI小组，UPCH的Gonzales博士和Hartinger博士以及JHU的William Checkley博士将在Steenland博士和Emory的其他人的支持下负责主要的研究项目。斯蒂兰德博士将为阿尔茨海默病和额颞叶痴呆症的研究提供主要支持。我们将把前任和实习生作为新的U01补助金的研究助理，致力于该补助金的主要项目，包括空气污染与心肺疾病、新冠肺炎、阿尔茨海默氏症和额颞痴呆的关联。UPCH将在智利大学团队的支持下协调本提案中的所有培训活动，智利大学团队在南美地区处于有利地位。拟议的培训活动将建立在我们先前工作的基础上，并将包括：1)为UPCH的研究生项目(硕士和博士级别)以及来自秘鲁、美国和智利的论文导师提供资金；2)为秘鲁研究人员提供一对一指导；以及3)在秘鲁、智利和美国举办短期课程，重点是发展与我们的研究活动相关的研究技能，包括我们的阿尔茨海默病研究项目。在项目期间，我们预计至少为167名受训人员提供短期培训，每年为25名秘鲁调查人员提供一对一培训机会，为6名学生提供硕士级别培训，为3名学生提供博士生培训。我们的所有培训活动将包括负责任地进行适应秘鲁科学背景的研究培训，并将包括秘鲁教员。我们将通过确定我们的目标在赠款期间是否实现来评估我们的计划。我们将在年度中心会议期间协调我们的活动，并根据管理活动的需要通过电子邮件和虚拟房间协调我们的活动。