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New England Regional Coordinating Center for the NINDS Stroke Trials Network

NINDS 卒中试验网络新英格兰地区协调中心

基本信息

批准号：
10457482
负责人：
ANEESH B SINGHAL
金额：
$ 33.72万
依托单位：
MASSACHUSETTS GENERAL HOSPITAL
依托单位国家：
美国
项目类别：
财政年份：
2018
资助国家：
美国
起止时间：
2018-08-01 至 2023-11-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10457482
关键词：
Achievement Acute Address Adult Advocacy American Heart Association Area Blood Vessels Boston Caring Child Childhood Clinical Clinical Investigator Clinical Research Clinical Trials Clinical Trials Network Clinical and Translational Science Awards Collaborations Community Hospitals Complement Discipline Discipline of Nursing Educational Activities Emergency Medicine Enrollment Environment Faculty Funding Future General Hospitals Goals Health Hospitals Infrastructure Inpatients Institution International Investigation Israel Lead Leadership Letters Maine Massachusetts Medical Medical center Mission Multicenter Trials National Institute of Neurological Disorders and Stroke Neurologist Neurology New England Operative Surgical Procedures Patient Care Patient-Focused Outcomes Patients Pediatric Hospitals Pediatrics Performance Phase Physicians Population Heterogeneity Populations at Risk Positioning Attribute Principal Investigator Protocols documentation Public Health Recording of previous events Records Recovery Recurrence Rehabilitation therapy Research Research Activity Research Infrastructure Research Institute Research Personnel Research Training Resources Role Rural Hospitals Science Seasons Site Stroke Stroke prevention StrokeNet clinical trials Study Section Talents Testing Training Training and Infrastructure Translating Translational Research United States National Institutes of Health Universities Vision Woman acute care base design early phase clinical trial early phase trial experience falls improved improved outcome innovation medical specialties member metropolitan multidisciplinary network models neuroimaging neurosurgery next generation novel novel therapeutics patient population phase III trial pre-clinical programs recruit research study skills stroke clinical trials stroke neurology stroke rehabilitation stroke risk stroke trials success telestroke translational therapeutics

项目摘要

We propose to continue the New England Regional Coordinating Center (NERCC), an integrated team of hospitals and EMS agencies in Boston and Western Massachusetts that will serve as a top-enrolling site and vibrant contributor to the NINDS Stroke Trials Network. Our group includes many of the major adult academic stroke centers in the Greater Boston area, and our 30+ hospital New England TeleStroke referral network will extend our potential recruitment even further. All core hospitals have a proven track record of successful management and performance of clinical trials. In particular, all hospitals have an established research infrastructure that performs ongoing clinical research in stroke neurology with strong collaborations across disciplines. Principal investigator Lee H. Schwamm, MD, and Co-Investigators bring a complementary set of skills in managing successful translational clinical research programs, membership on Steering Committees, and positions of national leadership in their fields. Our team includes seasoned clinical investigators in vascular neurology, emergency medicine, neuroendovascular, neurosurgery, neurointensive care, neuroimaging, stroke rehabilitation, and preclinical basic and translational stroke investigation in both adults and children. Strengths of the NERCC team include 1) close personal and professional ties between multiple investigators; 2) large patient population from diverse hospital settings in a major metropolitan area; 3) talented teams of site investigators with track records of scientific achievement, innovation, and subject recruitment in multicenter trials; 4) robust existing NINDS-funded research and clinical trial management infrastructure; 5) existing clinical research programs, e.g., Neurology Clinical Research Institute, NIH Clinical and Translational Science Award programs at Boston University and across Harvard; Sites in the SIREN and NeuroNEXT Clinical Coordinating Center. Overall, the NERCC Team has demonstrated outstanding commitment and performance in the first StrokeNet cycle, and has the resources, vision, and enthusiasm to continue to develop new translational science and successfully execute the NINDS StrokeNet Phase 1,2 and 3 trials.

我们建议继续新英格兰地区协调中心（NERCC），一个由