Biostatistics and Research Informatics Core

生物统计学和研究信息学核心

• 批准号: 10456957
• 负责人: Joycelynne Palmer
• 金额: $ 17.48万
• 依托单位: BECKMAN RESEARCH INSTITUTE/CITY OF HOPE
• 依托单位国家: 美国
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-09-02 至 2024-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10456957
• 关键词: Address; Adoption; Alabama; Algorithms; Amendment; Basic Science; Biometry; Biostatistics Core; Businesses; Cancer Center; Case Report Form; Cities; Clinical Research; Clinical Sciences; Clinical Trials; Collaborations; Complex; Computerized Medical Record; Consult; Core Grant; Custom; Data; Data Analyses; Data Collection; Data Pooling; Data Set; Database Management Systems; Databases; Development; Eligibility Determination; Ensure; Experimental Designs; Faculty; Genomics; Health Insurance Portability and Accountability Act; Hematologic Neoplasms; Immunologics; Informatics; Information Management; Information Technology; Infrastructure; Instruction; International; Investigation; Knowledge; Laboratories; Location; Logic; Lymphoma; Maintenance; Malignant lymphoid neoplasm; Management Information Systems; Manuscripts; Measures; Medidata; Metadata; Methods; Modeling; Monitor; Multicenter Studies; Nursing Research; Outcome; Patients; Pattern; Play; Preparation; Privacy; Process; Progress Reports; Protocols documentation; Publications; Registries; Reporting; Research; Research Activity; Research Design; Research Personnel; Resource Sharing; Resources; Role; Safety; Sample Size; Sampling; Security; Services; Site; Source; Specimen; Standardization; Statistical Data Interpretation; Statistical Models; Support System; System; Testing; Time; Tissue Banks; Tissues; Training; Translational Research; Universities; Validation; Visualization; Work; access restrictions; base; cohort; data access; data dictionary; data format; data handling; data integration; data management; data quality; data standards; design; disease registry; electronic data capture system; experience; innovation; interest; meetings; member; neoplasm registry; novel; programs; quality assurance; sound; web-accessible

SUMMARY CORE B Core B, the Biostatistics and Research Informatics Core of the City of Hope Lymphoma SPORE, provides information management and statistical expertise across all SPORE research activities, including study design, safety monitoring, data collection, data quality assurance, data analysis, and multicenter study site coordination. Core B will ensure that the proposed research hypotheses will be addressed with appropriate measures, tests, and interpretation, whether the data arise from genomic studies, basic science, translational, immunologic studies, or clinical trials. The centralized, comprehensive, and integrated framework of Core B assures each SPORE investigator access to statistical and informatics experts who have appropriate experience, interests and time to engage in the collaborative development of study designs, analysis plans, data analysis, interpretation, reporting, and abstract/manuscript preparation. Core B will also provide infrastructure for the management and integration of both existing and newly collected data and specimens through consistent and compatible data handling. The Core plays an integral role in the scientific development, execution, and analysis of all projects in the SPORE. Core B investigators have extensive experience in quantitative methods for biomedical applications, including clinical, basic, and translational science studies, with particular expertise in hematologic malignancy research. Core B is committed to collaboration to help ensure the scientific integrity of the SPORE investigations, by participating in regular Project and Program meetings, and providing rigorous and innovative input on all statistical and information management matters arising within the projects. The specific aims of Core B are as follows: Specific Aim 1. To support high quality data management through state-of-the-art information technologies, ensuring standardization, quality assurance, security, training, monitoring, data integration, decision support, reporting and multicenter coordination. Specific Aim 2. To provide biostatistical support to the Projects, Cores and Programs, by consulting on the design, data monitoring, analysis, statistical modeling, visualization, interpretation, reporting and publication of data generated by SPORE activities.

摘要核心b 核心B，希望城市淋巴瘤孢子的生物统计学和研究信息学核心提供 所有孢子研究活动的信息管理和统计专业知识，包括研究设计， 安全监控，数据收集，数据质量保证，数据分析和多中心研究网站 协调。核心B将确保提出的研究假设将在适当的情况下解决 措施，测试和解释，数据是否来自基因组研究，基础科学，翻译， 免疫学研究或临床试验。核心B的集中，全面和集成的框架 确保每个孢子调查员访问具有适当的统计和信息学专家 经验，兴趣和时间进行研究设计，分析计划， 数据分析，解释，报告和摘要/手稿准备。 核心B还将为现有和新收集的管理和集成提供基础架构 数据和标本通过一致和兼容的数据处理。核心在 对孢子中所有项目的科学开发，执行和分析。 B核B调查人员有 用于生物医学应用的定量方法的丰富经验，包括临床，基本和 翻译科学研究，在血液系统恶性研究方面具有特殊的专业知识。核心是 致力于合作，以帮助确保孢子调查的科学完整性，通过参与 定期项目和计划会议，并为所有统计和提供严格的创新投入 信息管理在项目中产生的重要问题。 核心B的具体目的如下： 特定目的1。通过最先进的信息技术支持高质量的数据管理， 确保标准化，质量保证，安全性，培训，监视，数据集成，决策支持， 报告和多中心协调。 特定目标2。通过就项目，核心和计划提供生物统计学支持。 设计，数据监控，分析，统计建模，可视化，解释，报告和报告 孢子活动产生的数据。