Pulmonary Biostatistics Core

项目摘要/摘要 核心E 该中心将为三个项目中每一个项目的严重哮喘调查人员提供所有方面的统计支持， 包括实验设计、分析和解释。核心人员将与PPG调查人员互动 在研究的所有阶段，包括提出研究问题和假设、实验设计、 数据管理、数据分析、结果解释、编写科学手稿和补助金， 结果的传播，以及对逐步成功和满足整体项目的障碍的评估 目标。具体目标是：(1)与项目调查人员合作，确保所有临床和 翻译研究和实验设计得当；(2)为项目调查人员提供支持 对实验和临床研究的数据进行统计分析和报告。这些目标将是 由博士(核心主任)赵毅和提供生物统计学硕士的James Slaven组成的团队完成 支持和专业知识。伊利诺伊大学没有类似的肺部数据分析核心，尽管有 计算生物学和生物信息学的补充计划。

PROJECT SUMMARY/ABSTRACT Core E The Core will provide severe asthma investigators from each of the three Projects all facets of statistical support, including experimental design, analysis, and interpretation. Core personnel will interact with PPG investigators in all stages of research, including the formulation of research questions and hypotheses, experimental design, data management, data analysis, result interpretation, preparation of scientific manuscripts and grants, dissemination of results, and the assessment of stepwise success and barriers to meeting overall project objectives. Specific aims are: (1) to collaborate with project investigators to ensure that all clinical and translational studies and experiments are properly designed, and (2) to provide support to project investigators in the statistical analysis and reporting of data from experiments and clinical studies. These aims will be accomplished by a team consisting of Yi Zhao, PhD (core director) and James Slaven, MS providing biostatistical support and expertise. There is no comparable core for pulmonary data analysis at IU, though there are complementary programs for Computational Biology and Bioinformatics.