CD-Cavs: Cross-Disciplinary Cardiovascular Sciences Training Program to Diversify the STEM workforce

克利夫兰州立大学（CSU）与克利夫兰诊所的勒纳研究所（LRI）一起， 提交"CD-Cavs：使STEM多样化的跨学科心血管科学培训计划 劳动力”。它的目的是培养博士前的学生从所有背景的代表性不足， STEM劳动力，从而帮助解决这些人口在STEM职业中的参与率低得令人无法接受的问题。 CSU是一所城市大学，其愿景是“以学生为中心的卓越学术中心， 为所有人提供可获得的、参与性的和特殊的教育"。在CSU的本科生中，39.6%符合佩尔的条件， 22%的少数民族（URM）。CSU服务于任何非多元化的学生团体， 俄亥俄州历史上的黑人大学。克利夫兰拥有丰富的生物医学和学术健康 沿着卫生技术走廊的机构，是对STEM感兴趣的学生的一个有吸引力的目的地， 健康护理在这个医疗保健领域，CSU与LRI的合作伙伴关系提供了丰富的培训环境： 凭借LRI卓越的NIH资助的心血管研究和强大的指导历史， CSU的卓越中心，如GRHD，健康和疾病基因调控中心， CHMS，人类机器系统中心。CD-Cavs将通过以下方式扩大与LRI的强大合作伙伴关系： 在其保护伞下，3个联合CSU：LRI博士。程序：监管生物学，临床和生物分析 化学，在科学与健康学院，（COSHP）和应用生物医学工程 沃什科维茨工程学院（WCOE）将专门招收代表性不足的学生 通过TRIO McNair奖学金计划，通过与LRI在国家会议上的联合营销，例如 少数民族学生年度生物医学研究会议（ABRCMS），并通过CSU学生 美国黑人工程师协会（National Society of Black Engineers）、美国女性工程师协会（Society of Women Engineers）等。 来自CSU的19名教师，加上来自LRI的18名教师将担任导师，每个CD-Cavs学员都将得到以下人员的支持： 一个鉴证组一个LRI导师CD-Cavs将是克利夫兰的第一个T32训练计划， 专门用于支持代表性不足的博士预科生。我们请求支持5个博士前 学生在每5年的CD-Cavs资金，将支持2 - 2.5年后通过 他们的候选资格考试。研究培训的广度包括基因表达的翻译控制， 复杂疾病的易感基因，衰老和生物钟，血液凝固障碍， 动脉粥样硬化和哮喘的炎症机制，肺动脉高压， 康复，微柱芯片上的3D生物打印，远程患者监测和组织基质工程。 这种独特的跨学科培训将通过克利夫兰的临床沉浸式体验来丰富 临床，由学生导师讨论组，心血管科学研讨会系列，心脏病学大 回合，加上从CSU的研究生资源中心多个支持机制。 !

Cleveland State University (CSU), together with the Lerner Research Institute (LRI) of the Cleveland Clinic, are submitting “CD-Cavs: Cross-Disciplinary Cardiovascular Sciences Training Program to Diversify the STEM workforce”. Its purpose is to train pre-doctoral students from all backgrounds under-represented in the STEM workforce, thus helping address unacceptably low participation of these populations in STEM careers. CSU is an urban university with a vision to be “a student-focused center of scholarly excellence that provides an accessible, engaged and exceptional education to all”. Of CSU’s undergraduates, 39.6% are Pell eligible, with 22% under-represented minorities (URM). CSU serves the most diverse student body of any non- historically black university in Ohio. Cleveland, with its abundance of biomedical and academic health institutions along the Health-Tech Corridor, is an attractive destination for students interested in STEM and healthcare. Within this healthcare landscape, CSU’s partnership with LRI provides a rich training environment: with LRI’s exceptional NIH-funded cardiovascular research and strong mentoring history, complemented by centers of excellence at CSU, such as GRHD, the Center for Gene Regulation in Health and Disease, and CHMS, the Center for Human Machine Systems. CD-Cavs will expand upon this robust partnership with LRI by bringing under its umbrella, the 3 joint CSU:LRI Ph.D. programs: Regulatory Biology, Clinical and Bioanalytical Chemistry, in the College of Sciences and Health Professions, (COSHP) and Applied Biomedical Engineering in the Washkewicz College of Engineering (WCOE). Underrepresented students, exclusively, will be recruited through TRIO McNair Scholar programs, through joint marketing with LRI at national conferences, such as Annual Biomedical Research Conference for Minority Students (ABRCMS), and through CSU student organizations such as Scientista, National Society of Black Engineers, and Society of Women Engineers. Nineteen faculty from CSU, plus 18 from LRI will serve as mentors, with each CD-Cavs trainee supported by one CSU and one LRI mentor. CD-Cavs will be the first T32 Training Program in Cleveland devoted exclusively to support of under-represented pre-doctoral students. We request support for 5 pre-doctoral students in each of the 5 years of CD-Cavs funding, to be supported for 2-2.5 years subsequent to passing their candidacy exam.The breadth of research training encompasses translational control of gene expression, susceptibility genes in complex diseases, aging and the circadian clock, blood coagulation disorders, inflammatory mechanisms in atherosclerosis and asthma, pulmonary hypertension, human-robot systems in rehabilitation, 3D-bioprinting on micro-pillar chips, remote patient monitoring, and tissue matrix engineering. This unique cross-disciplinary training will be enriched by a clinical immersion experience at the Cleveland Clinic, by Student-Mentor Discussion Groups, a Cardiovascular Sciences Seminar series, Cardiology Grand Rounds, plus multiple support mechanisms from CSU’s Graduate Student Resource Center. !